The Amyloid Precursor Protein (APP) Triplicated Gene Impairs Neuronal Precursor Differentiation and Neurite Development through Two Different Domains in the Ts65Dn Mouse Model for Down Syndrome

OLIG2 over-expression impairs proliferation of human Down syndrome neural progenitors

(2012) Jie Lu et al.   HUMAN MOLECULAR GENETICS

Secreted amyloid precursor proteins promote proliferation and glial differentiation of adult hippocampal neural progenitor cells

(2011) Sara Baratchi et al.   HIPPOCAMPUS

APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome

(2011) Stefania Trazzi et al.   HUMAN MOLECULAR GENETICS

Ascl1/Mash1 Is a Novel Target of Gli2 during Gli2-Induced Neurogenesis in P19 EC Cells

(2011) Anastassia Voronova et al.   PLoS One

S100B and APP Promote a Gliocentric Shift and Impaired Neurogenesis in Down Syndrome Neural Progenitors

(2011) Jie Lu et al.   PLoS One

The roles of amyloid precursor protein (APP) in neurogenesis

(2011) Zhi-dong Zhou et al.   Cell Adhesion & Migration

Widespread Proliferation Impairment and Hypocellularity in the Cerebellum of Fetuses with Down Syndrome

(2010) Sandra Guidi et al.   BRAIN PATHOLOGY

Involvement of notch signaling pathway in amyloid precursor protein induced glial differentiation

(2010) Young-Don Kwak et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Sonic hedgehog signaling regulates actin cytoskeleton via Tiam1–Rac1 cascade during spine formation

(2010) Nobunari Sasaki et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Amyloid-β Precursor Protein Induces Glial Differentiation of Neural Progenitor Cells by Activation of the IL-6/gp130 Signaling Pathway

(2010) Young-Don Kwak et al.   NEUROTOXICITY RESEARCH

Gene Network Disruptions and Neurogenesis Defects in the Adult Ts1Cje Mouse Model of Down Syndrome

(2010) Chelsee A. Hewitt et al.   PLoS One

Emerging mechanisms in morphogen-mediated axon guidance

(2009) Cristina Sánchez-Camacho et al.   BIOESSAYS

Lithium Restores Neurogenesis in the Subventricular Zone of the Ts65Dn Mouse, a Model for Down Syndrome

(2009) Patrizia Bianchi et al.   BRAIN PATHOLOGY

Meiotic behavior of aneuploid chromatin in mouse models of Down syndrome

(2009) Laura G. Reinholdt et al.   CHROMOSOMA

Region-specific Differentiation Potential of Adult Rat Spinal Cord Neural Stem/Precursors and Their Plasticity in Response to In Vitro Manipulation

(2009) Iris Kulbatski et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Sonic Hedgehog Is a Chemoattractant for Midbrain Dopaminergic Axons

(2009) Rachel Hammond et al.   PLoS One

The genetic architecture of Down syndrome phenotypes revealed by high-resolution analysis of human segmental trisomies

(2009) J. O. Korbel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell Cycle Elongation Impairs Proliferation of Cerebellar Granule Cell Precursors in the Ts65Dn Mouse, an Animal Model for Down Syndrome

(2008) Andrea Contestabile et al.   BRAIN PATHOLOGY

Mental retardation and associated neurological dysfunctions in Down syndrome: A consequence of dysregulation in critical chromosome 21 genes and associated molecular pathways

(2008) Mohammed Rachidi et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

The amyloid precursor protein intracellular domain (AICD) as modulator of gene expression, apoptosis, and cytoskeletal dynamics—Relevance for Alzheimer's disease

(2008) Thorsten Müller et al.   PROGRESS IN NEUROBIOLOGY