Gene Network Disruptions and Neurogenesis Defects in the Adult Ts1Cje Mouse Model of Down Syndrome

Function and regulation of Dyrk1A: towards understanding Down syndrome

(2009) Joongkyu Park et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Molecular genetic analysis of Down syndrome

(2009) David Patterson   HUMAN GENETICS

Proliferation deficits and gene expression dysregulation in Down's syndrome (Ts1Cje) neural progenitor cells cultured from neurospheres

(2009) Randal X. Moldrich et al.   JOURNAL OF NEUROSCIENCE RESEARCH

DYRK1A-Dosage Imbalance Perturbs NRSF/REST Levels, Deregulating Pluripotency and Embryonic Stem Cell Fate in Down Syndrome

(2008) Claudia Canzonetta et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Targeting Dyrk1A with AAVshRNA Attenuates Motor Alterations in TgDyrk1A, a Mouse Model of Down Syndrome

(2008) Jon Ortiz-Abalia et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cell Cycle Elongation Impairs Proliferation of Cerebellar Granule Cell Precursors in the Ts65Dn Mouse, an Animal Model for Down Syndrome

(2008) Andrea Contestabile et al.   BRAIN PATHOLOGY

The spatio-temporal and subcellular expression of the candidate Down syndrome gene Mnb/Dyrk1A in the developing mouse brain suggests distinct sequential roles in neuronal development

(2008) Barbara Hämmerle et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cholinergic degeneration and memory loss delayed by vitamin E in a Down syndrome mouse model

(2008) Jason Lockrow et al.   EXPERIMENTAL NEUROLOGY

Chronic pentylenetetrazole but not donepezil treatment rescues spatial cognition in Ts65Dn mice, a model for Down syndrome

(2008) N. Rueda et al.   NEUROSCIENCE LETTERS

CENP-O Class Proteins Form a Stable Complex and Are Required for Proper Kinetochore Function

(2007) Tetsuya Hori et al.   MOLECULAR BIOLOGY OF THE CELL