APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome

CB1Cannabinoid Receptors Increase Neuronal Precursor Proliferation through AKT/Glycogen Synthase Kinase-3β/β-Catenin Signaling

(2010) Stefania Trazzi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Early Pharmacotherapy Restores Neurogenesis and Cognitive Performance in the Ts65Dn Mouse Model for Down Syndrome

(2010) P. Bianchi et al.   JOURNAL OF NEUROSCIENCE

APP Intracellular Domain Impairs Adult Neurogenesis in Transgenic Mice by Inducing Neuroinflammation

(2010) Kaushik Ghosal et al.   PLoS One

Lithium Restores Neurogenesis in the Subventricular Zone of the Ts65Dn Mouse, a Model for Down Syndrome

(2009) Patrizia Bianchi et al.   BRAIN PATHOLOGY

Antitumor Effects of a Combined 5-Aza-2'Deoxycytidine and Valproic Acid Treatment on Rhabdomyosarcoma and Medulloblastoma in Ptch Mutant Mice

(2009) I. Ecke et al.   CANCER RESEARCH

Characterization of primary neurospheres generated from mouse ventral rostral hindbrain

(2009) Nadja Osterberg et al.   CELL AND TISSUE RESEARCH

Widespread impairment of cell proliferation in the neonate Ts65Dn mouse, a model for Down syndrome

(2009) A. Contestabile et al.   CELL PROLIFERATION

A Critical Period in Cortical Interneuron Neurogenesis in Down Syndrome Revealed by Human Neural Progenitor Cells

(2009) Anita Bhattacharyya et al.   DEVELOPMENTAL NEUROSCIENCE

Proliferation deficits and gene expression dysregulation in Down's syndrome (Ts1Cje) neural progenitor cells cultured from neurospheres

(2009) Randal X. Moldrich et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Abnormal Shh and FOXC2 expression correlates with aberrant lymphatic development in human fetuses with increased nuchal translucency

(2009) Yolanda M. de Mooij et al.   PRENATAL DIAGNOSIS

Methylation of PTCH1a gene in a subset of gastric cancers

(2009) Peng Du et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Cell Cycle Elongation Impairs Proliferation of Cerebellar Granule Cell Precursors in the Ts65Dn Mouse, an Animal Model for Down Syndrome

(2008) Andrea Contestabile et al.   BRAIN PATHOLOGY

PTCH1 duplication in a family with microcephaly and mild developmental delay

(2008) Katarzyna Derwińska et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

A neural crest deficit in Down syndrome mice is associated with deficient mitotic response to Sonic hedgehog

(2008) Randall J. Roper et al.   MECHANISMS OF DEVELOPMENT

Epigenetic interplay between histone modifications and DNA methylation in gene silencing

(2008) T VAISSIERE et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

The amyloid precursor protein intracellular domain (AICD) as modulator of gene expression, apoptosis, and cytoskeletal dynamics—Relevance for Alzheimer's disease

(2008) Thorsten Müller et al.   PROGRESS IN NEUROBIOLOGY

Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas

(2007) Joel I. Pritchard et al.   CANCER GENETICS AND CYTOGENETICS