A miniaturized screen for inhibitors of Jumonji histone demethylases

Iron-Mediated Cleavage of CC Bonds in Vicinal Tricarbonyl Compounds in Water

(2009) Jasmin Mecinović et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and activity of N-oxalylglycine and its derivatives as Jumonji C-domain-containing histone lysine demethylase inhibitors

(2009) Shohei Hamada et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294

(2009) Yanqi Chang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification and Characterization of Inhibitors of Human Apurinic/apyrimidinic Endonuclease APE1

(2009) Anton Simeonov et al.   PLoS One

Kinetic characterization and identification of a novel inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 using a time-resolved fluorescence resonance energy transfer-based assay technology

(2008) Jennifer H. Dao et al.   ANALYTICAL BIOCHEMISTRY

Prolyl 4-hydroxylases, key enzymes in the synthesis of collagens and regulation of the response to hypoxia, and their roles as treatment targets

(2008) Johanna Myllyharju   ANNALS OF MEDICINE

A Robotic Platform for Quantitative High-Throughput Screening

(2008) Sam Michael et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease

(2008) P. A.C. Cloos et al.   GENES & DEVELOPMENT

Inhibitor Scaffolds for 2-Oxoglutarate-Dependent Histone Lysine Demethylases⊥

(2008) Nathan R. Rose et al.   JOURNAL OF MEDICINAL CHEMISTRY

Baicalein Induces Functional Hypoxia-Inducible Factor-1  and Angiogenesis

(2008) H. Cho et al.   MOLECULAR PHARMACOLOGY

Expanding chemical biology of 2-oxoglutarate oxygenases

(2008) Christoph Loenarz et al.   Nature Chemical Biology

Baicalein suppresses hypoxia-induced HIF-1α protein accumulation and activation through inhibition of reactive oxygen species and PI 3-kinase/Akt pathway in BV2 murine microglial cells

(2008) Keun Young Hwang et al.   NEUROSCIENCE LETTERS

Compound Management for Quantitative High-Throughput Screening

(2008) A YASGAR   Journal of the Association for Laboratory Automation.

Flavonoids induce HIF-1α but impair its nuclear accumulation and activity

(2007) Anastasia Triantafyllou et al.   FREE RADICAL BIOLOGY AND MEDICINE