Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors
Published 2010 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors
Authors
Keywords
-
Journal
PLoS One
Volume 5, Issue 11, Pages e15535
Publisher
Public Library of Science (PLoS)
Online
2010-11-24
DOI
10.1371/journal.pone.0015535
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Reversal of Histone Methylation: Biochemical and Molecular Mechanisms of Histone Demethylases
- (2010) Nima Mosammaparast et al. Annual Review of Biochemistry
- Utilization of an In Vivo Reporter for High Throughput Identification of Branched Small Molecule Regulators of Hypoxic Adaptation
- (2010) Natalya A. Smirnova et al. CHEMISTRY & BIOLOGY
- Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents
- (2010) Jiahuai Tan et al. Journal of Hematology & Oncology
- Selective Inhibitors of the JMJD2 Histone Demethylases: Combined Nondenaturing Mass Spectrometric Screening and Crystallographic Approaches
- (2010) Nathan R. Rose et al. JOURNAL OF MEDICINAL CHEMISTRY
- Design, Synthesis, Enzyme-Inhibitory Activity, and Effect on Human Cancer Cells of a Novel Series of Jumonji Domain-Containing Protein 2 Histone Demethylase Inhibitors
- (2010) Shohei Hamada et al. JOURNAL OF MEDICINAL CHEMISTRY
- Crystal structures of human FIH-1 in complex with quinol family inhibitors
- (2010) Hyunjin Moon et al. MOLECULES AND CELLS
- Synthesis and activity of N-oxalylglycine and its derivatives as Jumonji C-domain-containing histone lysine demethylase inhibitors
- (2009) Shohei Hamada et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Inhibition of the histone lysine demethylase JMJD2A by ejection of structural Zn(ii)
- (2009) Rok Sekirnik et al. CHEMICAL COMMUNICATIONS
- Application of a Proteolysis/Mass Spectrometry Method for Investigating the Effects of Inhibitors on Hydroxylase Structure
- (2009) Christopher J. Stubbs et al. JOURNAL OF MEDICINAL CHEMISTRY
- A miniaturized screen for inhibitors of Jumonji histone demethylases
- (2009) Masaaki Sakurai et al. Molecular BioSystems
- Role of Jhdm2a in regulating metabolic gene expression and obesity resistance
- (2009) Keisuke Tateishi et al. NATURE
- A Robotic Platform for Quantitative High-Throughput Screening
- (2008) Sam Michael et al. ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
- Dynamic protein methylation in chromatin biology
- (2008) S. S. Ng et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The human oxygen sensing machinery and its manipulation
- (2008) Rasheduzzaman Chowdhury et al. CHEMICAL SOCIETY REVIEWS
- Dynamic states of the DNA repair enzyme AlkB regulate product release
- (2008) Boris Bleijlevens et al. EMBO REPORTS
- Chromatin-modifying enzymes as therapeutic targets – Part 1
- (2008) Brian R Keppler et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
- (2008) P. A.C. Cloos et al. GENES & DEVELOPMENT
- Evidence That Two Enzyme-derived Histidine Ligands Are Sufficient for Iron Binding and Catalysis by Factor Inhibiting HIF (FIH)
- (2008) Kirsty S. Hewitson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibitor Scaffolds for 2-Oxoglutarate-Dependent Histone Lysine Demethylases⊥
- (2008) Nathan R. Rose et al. JOURNAL OF MEDICINAL CHEMISTRY
- Fluorescence Spectroscopic Profiling of Compound Libraries
- (2008) Anton Simeonov et al. JOURNAL OF MEDICINAL CHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation