Phosphorylation of Human Cytochrome P450c17 by p38α Selectively Increases 17,20 Lyase Activity and Androgen Biosynthesis

Substrate-modulated Cytochrome P450 17A1 and Cytochromeb5Interactions Revealed by NMR

(2013) D. Fernando Estrada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development

(2013) Leonardo Guasti et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

SET/PP2A system regulates androgen production in ovarian follicles in vitro

(2013) Ling-Ling Gao et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The Action of Cytochrome b5 on CYP2E1 and CYP2C19 Activities Requires Anionic Residues D58 and D65

(2012) Hwei-Ming Peng et al.   BIOCHEMISTRY

Insulin Resistance and the Polycystic Ovary Syndrome Revisited: An Update on Mechanisms and Implications

(2012) Evanthia Diamanti-Kandarakis et al.   ENDOCRINE REVIEWS

Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001

(2012) Natasha M. DeVore et al.   NATURE

Detection of a Protein Conformational Equilibrium by Electrospray Ionisation-Ion Mobility-Mass Spectrometry

(2011) Matthew Jenner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders

(2011) Walter L. Miller et al.   ENDOCRINE REVIEWS

High-Yield Expression of a Catalytically Active Membrane-Bound Protein: Human P450 Oxidoreductase

(2011) Duanpen Sandee et al.   ENDOCRINOLOGY

Premature adrenarche: novel lessons from early onset androgen excess

(2011) Jan Idkowiak et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency

(2011) C. Xia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms and functions of p38 MAPK signalling

(2010) Ana Cuadrado et al.   BIOCHEMICAL JOURNAL

Impact of Differential P450c17 Phosphorylation by cAMP Stimulation and by Starvation Conditions on Enzyme Activities and Androgen Production in NCI-H295R Cells

(2010) Petra Kempná et al.   ENDOCRINOLOGY

Human Cytochrome P450c17: Single Step Purification and Phosphorylation of Serine 258 by Protein Kinase A

(2010) Yue-Hao Wang et al.   ENDOCRINOLOGY

Domain Motion in Cytochrome P450 Reductase

(2009) Jacqueline Ellis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathways Leading to Phosphorylation of P450c17 and to the Posttranslational Regulation of Androgen Biosynthesis

(2008) Meng Kian Tee et al.   ENDOCRINOLOGY

p38-Mitogen-Activated Protein Kinase Stimulated Steroidogenesis in Granulosa Cell-Oocyte Cocultures: Role of Bone Morphogenetic Proteins 2 and 4

(2008) Kenichi Inagaki et al.   ENDOCRINOLOGY

The serine phosphorylation hypothesis of polycystic ovary syndrome: a unifying mechanism for hyperandrogenemia and insulin resistance

(2008) Andrew A. Bremer et al.   FERTILITY AND STERILITY

Androgen synthesis in adrenarche

(2008) Walter L. Miller   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS