6′-Guanidinonaltrindole (6′-GNTI) Is a G Protein-biased κ-Opioid Receptor Agonist That Inhibits Arrestin Recruitment
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Title
6′-Guanidinonaltrindole (6′-GNTI) Is a G Protein-biased κ-Opioid Receptor Agonist That Inhibits Arrestin Recruitment
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 287, Issue 32, Pages 27050-27054
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2012-06-27
DOI
10.1074/jbc.c112.387332
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- Therapeutic potential of β-arrestin- and G protein-biased agonists
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- (2009) Todd W. Vanderah CLINICAL JOURNAL OF PAIN
- Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking
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