6′-Guanidinonaltrindole (6′-GNTI) Is a G Protein-biased κ-Opioid Receptor Agonist That Inhibits Arrestin Recruitment

Deciphering biased-agonism complexity reveals a new active AT1 receptor entity

(2012) Aude Saulière et al.   Nature Chemical Biology

Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues

(2011) Cécile Béguin et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Regulation of  -Opioid Receptor Signaling in Peripheral Sensory Neurons In Vitro and In Vivo

(2011) K. A. Berg et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Functional Selectivity at the  -Opioid Receptor: Implications for Understanding Opioid Analgesia and Tolerance

(2011) K. M. Raehal et al.   PHARMACOLOGICAL REVIEWS

Discovery of  -Arrestin-Biased Dopamine D2 Ligands for Probing Signal Transduction Pathways Essential for Antipsychotic Efficacy

(2011) J. A. Allen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of κ-opioid receptor activation in mediating antinociception and addiction

(2010) Yu-hua Wang et al.   ACTA PHARMACOLOGICA SINICA

Morphine-like Opiates Selectively Antagonize Receptor-Arrestin Interactions

(2010) Paola Molinari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics

(2010) Kirsten M. Raehal et al.   NEUROPHARMACOLOGY

The Therapeutic Potential of κ-Opioids for Treatment of Pain and Addiction

(2010) Charles Chavkin   NEUROPSYCHOPHARMACOLOGY

Consequences of opioid receptor mutation on actions of univalent and bivalent kappa and delta ligands

(2010) Michael A. Ansonoff et al.   PSYCHOPHARMACOLOGY

Kinase cascades and ligand-directed signaling at the kappa opioid receptor

(2010) Michael R. Bruchas et al.   PSYCHOPHARMACOLOGY

Therapeutic potential of β-arrestin- and G protein-biased agonists

(2010) Erin J. Whalen et al.   TRENDS IN MOLECULAR MEDICINE

Delta and Kappa Opioid Receptors as Suitable Drug Targets for Pain

(2009) Todd W. Vanderah   CLINICAL JOURNAL OF PAIN

Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking

(2009) Benjamin B. Land et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dopamine D2 receptors form higher order oligomers at physiological expression levels

(2008) Wen Guo et al.   EMBO JOURNAL

The Dysphoric Component of Stress Is Encoded by Activation of the Dynorphin  -Opioid System

(2008) B. B. Land et al.   JOURNAL OF NEUROSCIENCE

Recruitment of β-arrestin2 to the dopamine D2 receptor: Insights into anti-psychotic and anti-parkinsonian drug receptor signaling

(2008) I KLEWE et al.   NEUROPHARMACOLOGY