The HtrA Protease fromStreptococcus pneumoniaeDigests Both Denatured Proteins and the Competence-stimulating Peptide

Newly folded substrates inside the molecular cage of the HtrA chaperone DegQ

(2012) Hélène Malet et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cage assembly of DegP protease is not required for substrate-dependent regulation of proteolytic activity or high-temperature cell survival

(2012) S. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid paracellular transmigration of Campylobacter jejuni across polarized epithelial cells without affecting TER: role of proteolytic-active HtrA cleaving E-cadherin but not fibronectin

(2012) Manja Boehm et al.   Gut Pathogens

Recombinant Deg/HtrA proteases fromSynechocystissp. PCC 6803 differ in substrate specificity, biochemical characteristics and mechanism

(2011) Pitter F. Huesgen et al.   BIOCHEMICAL JOURNAL

Covalent Linkage of Distinct Substrate Degrons Controls Assembly and Disassembly of DegP Proteolytic Cages

(2011) Seokhee Kim et al.   CELL

Molecular Adaptation of the DegQ Protease to Exert Protein Quality Control in the Bacterial Cell Envelope

(2011) Justyna Sawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Solution structure of HtrA PDZ domain from Streptococcus pneumoniae and its interaction with YYF–COOH containing peptides

(2011) Kai Fan et al.   JOURNAL OF STRUCTURAL BIOLOGY

Membrane-associated DegP in Bordetella chaperones a repeat-rich secretory protein

(2011) Catherine Baud et al.   MOLECULAR MICROBIOLOGY

HTRA proteases: regulated proteolysis in protein quality control

(2011) Tim Clausen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Unique Residues Involved in Activation of the Multitasking Protease/Chaperone HtrA from Chlamydia trachomatis

(2011) Wilhelmina M. Huston et al.   PLoS One

The Legionella HtrA homologue DegQ is a self-compartmentizing protease that forms large 12-meric assemblies

(2011) R. Wrase et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid Pneumococcal Evolution in Response to Clinical Interventions

(2011) N. J. Croucher et al.   SCIENCE

Competence in Streptococcus pneumoniae Is Regulated by the Rate of Ribosomal Decoding Errors

(2011) K. E. Stevens et al.   mBio

Dynamic Distribution of the SecA and SecY Translocase Subunits and Septal Localization of the HtrA Surface Chaperone/Protease during Streptococcus pneumoniae D39 Cell Division

(2011) H.-C. T. Tsui et al.   mBio

Helicobacter pylori HtrA is a new secreted virulence factor that cleaves E-cadherin to disrupt intercellular adhesion

(2010) Benjamin Hoy et al.   EMBO REPORTS

Determinants of structural and functional plasticity of a widely conserved protease chaperone complex

(2010) Melisa Merdanovic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis of substrate specificity in the serine proteases

(2010) John J. Perona et al.   PROTEIN SCIENCE

Bowl-shaped oligomeric structures on membranes as DegP's new functional forms in protein quality control

(2009) Q.-T. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allosteric Activation of HtrA Protease DegP by Stress Signals during Bacterial Protein Quality Control

(2008) Michael Meltzer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Streptococcus pneumoniae Competence Regulatory System Influences Respiratory Tract Colonization

(2008) J. E. Kowalko et al.   INFECTION AND IMMUNITY

Structural basis for the regulated protease and chaperone function of DegP

(2008) Tobias Krojer et al.   NATURE

Activation of DegP chaperone-protease via formation of large cage-like oligomers upon binding to substrate proteins

(2008) J. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA