Functional Homomers and Heteromers of Dopamine D2Land D3Receptors Co-exist at the Cell Surface

Unidirectional Cross-Activation of GRPR by MOR1D Uncouples Itch and Analgesia Induced by Opioids

(2011) Xian-Yu Liu et al.   CELL

AT1R-CB1R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II

(2011) Raphael Rozenfeld et al.   EMBO JOURNAL

Functional potencies of dopamine agonists and antagonists at human dopamine D2 and D3 receptors

(2011) Yoshihiro Tadori et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Separation and reformation of cell surface dopamine receptor oligomers visualized in cells

(2011) Brian F. O'Dowd et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Dopamine D4 receptor oligomerization - contribution to receptor biogenesis

(2011) Kathleen Van Craenenbroeck et al.   FEBS Journal

Heteromultimerization of Cannabinoid CB1Receptor and Orexin OX1Receptor Generates a Unique Complex in Which Both Protomers Are Regulated by Orexin A

(2011) Richard J. Ward et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Full characterization of GPCR monomer–dimer dynamic equilibrium by single molecule imaging

(2011) Rinshi S. Kasai et al.   JOURNAL OF CELL BIOLOGY

CODA-RET reveals functional selectivity as a result of GPCR heteromerization

(2011) Eneko Urizar et al.   Nature Chemical Biology

Asymmetry of GPCR oligomers supports their functional relevance

(2011) Pascal Maurice et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Dopamine D1-D2 receptor heteromer signaling pathway in the brain: emerging physiological relevance

(2011) Ahmed Hasbi et al.   Molecular Brain

Applications of fluorescence and bioluminescence resonance energy transfer to drug discovery at G protein coupled receptors

(2010) Elisa Alvarez-Curto et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Ligand-induced internalization of the orexin OX1 and cannabinoid CB1 receptors assessed via N-terminal SNAP and CLIP-tagging

(2010) Richard J Ward et al.   BRITISH JOURNAL OF PHARMACOLOGY

Dopamine Receptor Homooligomers and Heterooligomers in Schizophrenia

(2010) Melissa L. Perreault et al.   CNS Neuroscience & Therapeutics

Time-resolved FRET between GPCR ligands reveals oligomers in native tissues

(2010) Laura Albizu et al.   Nature Chemical Biology

Allostery at G Protein-Coupled Receptor Homo- and Heteromers: Uncharted Pharmacological Landscapes

(2010) N. J. Smith et al.   PHARMACOLOGICAL REVIEWS

Formation and dissociation of M1 muscarinic receptor dimers seen by total internal reflection fluorescence imaging of single molecules

(2010) J. A. Hern et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased Abundance of Opioid Receptor Heteromers After Chronic Morphine Administration

(2010) A. Gupta et al.   Science Signaling

[3H]4-(dimethylamino)-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl) butyl)benzamide: A selective radioligand for dopamine D3receptors. II. Quantitative analysis of dopamine D3and D2receptor density ratio in the caudate-putamen

(2010) Jinbin Xu et al.   SYNAPSE

Cocaine self-administration markedly increases dopamine D2receptor negative cooperativity for dopamine binding: A receptor dimer-based analysis

(2010) Rafael Franco et al.   SYNAPSE

Schizophrenia, amphetamine-induced sensitized state and acute amphetamine exposure all show a common alteration: increased dopamine D2 receptor dimerization

(2010) Min Wang et al.   Molecular Brain

GPCR Theme Editorial

(2009) G Milligan et al.   BRITISH JOURNAL OF PHARMACOLOGY

G protein-coupled receptor hetero-dimerization: contribution to pharmacology and function

(2009) Graeme Milligan   BRITISH JOURNAL OF PHARMACOLOGY

Dopamine D2–D3 receptor heteromers: pharmacological properties and therapeutic significance

(2009) Roberto Maggio et al.   CURRENT OPINION IN PHARMACOLOGY

Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation

(2009) Yang Han et al.   Nature Chemical Biology

Analysis of receptor oligomerization by FRAP microscopy

(2009) Sandra Dorsch et al.   NATURE METHODS

Heterodimerization of dopamine receptors: new insights into functional and therapeutic significance

(2009) Roberto Maggio et al.   PARKINSONISM & RELATED DISORDERS

Dopamine D2 receptors form higher order oligomers at physiological expression levels

(2008) Wen Guo et al.   EMBO JOURNAL

G Protein Coupling and Ligand Selectivity of the D2L and D3 Dopamine Receptors

(2008) J. R. Lane et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization

(2008) Damien Maurel et al.   NATURE METHODS

Partial agonist actions at dopamine D2L receptors are modified by co-transfection of D3 receptors: Potential role of heterodimer formation

(2008) Roberto Maggio et al.   PARKINSONISM & RELATED DISORDERS