A river model to map convergent cancer evolution and guide therapy in RCC
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Title
A river model to map convergent cancer evolution and guide therapy in RCC
Authors
Keywords
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Journal
Nature Reviews Urology
Volume 12, Issue 12, Pages 706-712
Publisher
Springer Nature
Online
2015-11-03
DOI
10.1038/nrurol.2015.260
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- (2014) L Melchor et al. LEUKEMIA
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- (2014) Dejan Juric et al. NATURE
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- (2014) S. Misale et al. Cancer Discovery
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- (2014) Alexander Sankin et al. Cancer Medicine
- Cancer heterogeneity: implications for targeted therapeutics
- (2013) R Fisher et al. BRITISH JOURNAL OF CANCER
- Novel Approaches Targeting the Vascular Endothelial Growth Factor Axis in Renal Cell Carcinoma
- (2013) Martin H. Voss et al. CANCER JOURNAL
- Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators BAP1 and SETD2: A Report by MSKCC and the KIRC TCGA Research Network
- (2013) A. A. Hakimi et al. CLINICAL CANCER RESEARCH
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- (2013) Pierre Martinez et al. JOURNAL OF PATHOLOGY
- A clear picture of renal cell carcinoma
- (2013) A Ari Hakimi et al. NATURE GENETICS
- Pazopanib versus Sunitinib in Metastatic Renal-Cell Carcinoma
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- (2012) C. Swanton CANCER RESEARCH
- Clinical and Pathologic Impact of Select Chromatin-modulating Tumor Suppressors in Clear Cell Renal Cell Carcinoma
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- How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine
- (2010) M Gerlinger et al. BRITISH JOURNAL OF CANCER
- The patterns and dynamics of genomic instability in metastatic pancreatic cancer
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