Does lipopolysaccharide-mediated inflammation have a role in OA?

The gut microbiota and inflammatory noncommunicable diseases: Associations and potentials for gut microbiota therapies

(2015) Christina E. West et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Impact of training status on LPS-induced acute inflammation in humans

(2015) J. Olesen et al.   JOURNAL OF APPLIED PHYSIOLOGY

Attentuation of hyaluronan fragment induced inflammatory response in macrophages by chondroitin sulphate

(2015) T. Stabler et al.   OSTEOARTHRITIS AND CARTILAGE

Bioactivity in an Aggrecan 32-mer Fragment Is Mediated via Toll-like Receptor 2

(2015) Sophie Lees et al.   Arthritis & Rheumatology

Soluble Macrophage Biomarkers Indicate Inflammatory Phenotypes in Patients With Knee Osteoarthritis

(2015) Hikmat N. Daghestani et al.   Arthritis & Rheumatology

Effects of Antibiotics on Human Microbiota and Subsequent Disease

(2014) Kristie M. Keeney et al.   Annual Review of Microbiology

Monocytes from Metabolic Syndrome Subjects Exhibit a Proinflammatory M1 Phenotype

(2014) Xinpu Chen et al.   Metabolic Syndrome and Related Disorders

TLR4 signalling in osteoarthritis—finding targets for candidate DMOADs

(2014) Rodolfo Gómez et al.   Nature Reviews Rheumatology

Treatment efficacy of adipose-derived stem cells in experimental osteoarthritis is driven by high synovial activation and reflected by S100A8/A9 serum levels

(2014) R.F. Schelbergen et al.   OSTEOARTHRITIS AND CARTILAGE

Bariatric surgery decreased the serum level of an endotoxin-associated marker: lipopolysaccharide-binding protein

(2014) Po-Jen Yang et al.   Surgery for Obesity and Related Diseases

Exercise-mediated changes in high-density lipoprotein: Impact on form and function

(2013) Alisa Blazek et al.   AMERICAN HEART JOURNAL

Fecal Microbiota Transplantation for Clostridium difficile Infection: Systematic Review and Meta-Analysis

(2013) Zain Kassam et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Proteomic Analysis of Synovial Fluid From the Osteoarthritic Knee: Comparison With Transcriptome Analyses of Joint Tissues

(2013) Susan Y. Ritter et al.   ARTHRITIS AND RHEUMATISM

Serum lipopolysaccharide-binding protein as a marker of atherosclerosis

(2013) Marta Serrano et al.   ATHEROSCLEROSIS

Protein selection and export via outer membrane vesicles

(2013) K.E. Bonnington et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Toll-like Receptor Status in Obesity and Metabolic Syndrome: A Translational Perspective

(2013) Ishwarlal Jialal et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Increased circulatory levels of lipopolysaccharide (LPS) and zonulin signify novel biomarkers of proinflammation in patients with type 2 diabetes

(2013) B. Jayashree et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Direct in vivo evidence of activated macrophages in human osteoarthritis

(2013) V. Byers Kraus et al.   OSTEOARTHRITIS AND CARTILAGE

Recurrent Exposure to Subclinical Lipopolysaccharide Increases Mortality and Induces Cardiac Fibrosis in Mice

(2013) Wilbur Y. W. Lew et al.   PLoS One

Bacterial lipopolysaccharides form procollagen-endotoxin complexes that trigger cartilage inflammation and degeneration: implications for the development of rheumatoid arthritis

(2013) Wolfgang Lorenz et al.   ARTHRITIS RESEARCH & THERAPY

Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

(2013) Jose U Scher et al.   eLife

Synovial fluid from patients with early osteoarthritis modulates fibroblast-like synoviocyte responses to Toll-like receptor 4 and Toll-like receptor 2 ligands via soluble CD14

(2012) Anjali Nair et al.   ARTHRITIS AND RHEUMATISM

Does endotoxaemia contribute to osteoarthritis in obese patients?

(2012) David Metcalfe et al.   CLINICAL SCIENCE

Increased Toll-Like Receptor Activity in Patients With Metabolic Syndrome

(2012) I. Jialal et al.   DIABETES CARE

The gut microbiota, obesity and insulin resistance

(2012) Jian Shen et al.   MOLECULAR ASPECTS OF MEDICINE

Adaptive immunity in obesity and insulin resistance

(2012) Henrike Sell et al.   Nature Reviews Endocrinology

Pre-rheumatoid arthritis: predisposition and transition to clinical synovitis

(2012) William P. Arend et al.   Nature Reviews Rheumatology

Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2

(2012) U. Ohto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of osteoarthritis and metabolic inflammation by a very high-fat diet in mice: Effects of short-term exercise

(2011) Timothy M. Griffin et al.   ARTHRITIS AND RHEUMATISM

Active involvement of alarmins S100A8 and S100A9 in the regulation of synovial activation and joint destruction during mouse and human osteoarthritis

(2011) Peter L. E. M. van Lent et al.   ARTHRITIS AND RHEUMATISM

Alarmins S100A8 and S100A9 elicit a catabolic effect in human osteoarthritic chondrocytes that is dependent on Toll-like receptor 4

(2011) Rik F. P. Schelbergen et al.   ARTHRITIS AND RHEUMATISM

Physical Exercise Reduces Circulating Lipopolysaccharide and TLR4 Activation and Improves Insulin Signaling in Tissues of DIO Rats

(2011) Alexandre G. Oliveira et al.   DIABETES

High Fat Intake Leads to Acute Postprandial Exposure to Circulating Endotoxin in Type 2 Diabetic Subjects

(2011) A. L. Harte et al.   DIABETES CARE

Endotoxemia Is Associated With an Increased Risk of Incident Diabetes

(2011) P. J. Pussinen et al.   DIABETES CARE

Rifaximin reduces endotoxemia and improves liver function and disease severity in patients with decompensated cirrhosis

(2011) Georgios N. Kalambokis et al.   HEPATOLOGY

Mode and place of delivery, gastrointestinal microbiota, and their influence on asthma and atopy

(2011) Frederika A. van Nimwegen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Identification of a Panel of Novel Serum Osteoarthritis Biomarkers

(2011) Patricia Fernández-Puente et al.   JOURNAL OF PROTEOME RESEARCH

Identification of a central role for complement in osteoarthritis

(2011) Qian Wang et al.   NATURE MEDICINE

Propensity to high-fat diet-induced obesity in rats is associated with changes in the gut microbiota and gut inflammation

(2010) Claire Barbier de La Serre et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The role of synovial macrophages and macrophage-produced mediators in driving inflammatory and destructive responses in osteoarthritis

(2010) Jan Bondeson et al.   ARTHRITIS AND RHEUMATISM

Enterobacteriaceae Act in Concert with the Gut Microbiota to Induce Spontaneous and Maternally Transmitted Colitis

(2010) Wendy S. Garrett et al.   Cell Host & Microbe

Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism

(2010) Sylvie Rabot et al.   FASEB JOURNAL

Endogenous toll-like receptor ligands and their biological significance

(2010) Li Yu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Elevated endotoxin levels in non-alcoholic fatty liver disease

(2010) Alison L Harte et al.   Journal of Inflammation-London

Endotoxin levels correlate positively with a sedentary lifestyle and negatively with highly trained subjects

(2010) Fabio S Lira et al.   Lipids in Health and Disease

The endocannabinoid system links gut microbiota to adipogenesis

(2010) Giulio G Muccioli et al.   Molecular Systems Biology

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

(2010) Mohit Kapoor et al.   Nature Reviews Rheumatology

Association between weight or body mass index and hand osteoarthritis: a systematic review

(2009) E. Yusuf et al.   ANNALS OF THE RHEUMATIC DISEASES

Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis

(2009) Timothy M. Griffin et al.   ARTHRITIS AND RHEUMATISM

Experimental Endotoxemia Induces Adipose Inflammation and Insulin Resistance in Humans

(2009) N. N. Mehta et al.   DIABETES

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

Differential Toll-like receptor-dependent collagenase expression in chondrocytes

(2008) Q Zhang et al.   ANNALS OF THE RHEUMATIC DISEASES

Ethnic and sex differences in circulating endotoxin levels: A novel marker of atherosclerotic and cardiovascular risk in a British multi-ethnic population

(2008) Michelle A. Miller et al.   ATHEROSCLEROSIS

Influence of dietary fatty acids on endocannabinoid and N-acylethanolamine levels in rat brain, liver and small intestine

(2008) Andreas Artmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Innate immune system activation in osteoarthritis: is osteoarthritis a chronic wound?

(2008) Carla R Scanzello et al.   CURRENT OPINION IN RHEUMATOLOGY

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

(2008) P. D. Cani et al.   DIABETES

Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice

(2008) Mathieu Membrez et al.   FASEB JOURNAL

Proteomic analysis of the LPS-induced stress response in rat chondrocytes reveals induction of innate immune response components in articular cartilage

(2007) Lisbet Haglund et al.   MATRIX BIOLOGY