Does endotoxaemia contribute to osteoarthritis in obese patients?

Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases

(2011) Wang Hui et al.   ANNALS OF THE RHEUMATIC DISEASES

Induction of osteoarthritis and metabolic inflammation by a very high-fat diet in mice: Effects of short-term exercise

(2011) Timothy M. Griffin et al.   ARTHRITIS AND RHEUMATISM

High Fat Intake Leads to Acute Postprandial Exposure to Circulating Endotoxin in Type 2 Diabetic Subjects

(2011) A. L. Harte et al.   DIABETES CARE

Endotoxemia Is Associated With an Increased Risk of Incident Diabetes

(2011) P. J. Pussinen et al.   DIABETES CARE

Acute and chronic saturated fatty acid treatment as a key instigator of the TLR-mediated inflammatory response in human adipose tissue, in vitro

(2011) Elham M. Youssef-Elabd et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Association of Knee Osteoarthritis with the Accumulation of Metabolic Risk Factors Such as Overweight, Hypertension, Dyslipidemia, and Impaired Glucose Tolerance in Japanese Men and Women: The ROAD Study

(2011) NORIKO YOSHIMURA et al.   JOURNAL OF RHEUMATOLOGY

Elevated endotoxin levels in non-alcoholic fatty liver disease

(2010) Alison L Harte et al.   Journal of Inflammation-London

Endotoxin levels correlate positively with a sedentary lifestyle and negatively with highly trained subjects

(2010) Fabio S Lira et al.   Lipids in Health and Disease

The infrapatellar fat pad in knee osteoarthritis: An important source of interleukin-6 and its soluble receptor

(2009) Emilie Distel et al.   ARTHRITIS AND RHEUMATISM

Local cytokine profiles in knee osteoarthritis: elevated synovial fluid interleukin-15 differentiates early from end-stage disease

(2009) C.R. Scanzello et al.   OSTEOARTHRITIS AND CARTILAGE

Changes in intestinal mucosal immune barrier in rats withendotoxemia

(2009) Chong Liu et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Ethnic and sex differences in circulating endotoxin levels: A novel marker of atherosclerotic and cardiovascular risk in a British multi-ethnic population

(2008) Michelle A. Miller et al.   ATHEROSCLEROSIS

Chylomicrons promote intestinal absorption of lipopolysaccharides

(2008) Sarbani Ghoshal et al.   JOURNAL OF LIPID RESEARCH