Flavoproteins Are Potential Targets for the Antibiotic Roseoflavin in Escherichia coli

The Flavoenzyme Azobenzene Reductase AzoR from Escherichia coli Binds Roseoflavin Mononucleotide (RoFMN) with High Affinity and Is Less Active in Its RoFMN Form

(2013) Simone Langer et al.   BIOCHEMISTRY

Riboflavin Analogs as Antiinfectives: Occurrence, Mode of Action, Metabolism and Resistance

(2013) Danielle Biscaro Pedrolli et al.   CURRENT PHARMACEUTICAL DESIGN

Genome Sequence of the Bacterium Streptomyces davawensis JCM 4913 and Heterologous Production of the Unique Antibiotic Roseoflavin

(2012) F. Jankowitsch et al.   JOURNAL OF BACTERIOLOGY

A highly specialized flavin mononucleotide riboswitch responds differently to similar ligands and confers roseoflavin resistance to Streptomyces davawensis

(2012) Danielle Biscaro Pedrolli et al.   NUCLEIC ACIDS RESEARCH

EcoCyc: fusing model organism databases with systems biology

(2012) Ingrid M. Keseler et al.   NUCLEIC ACIDS RESEARCH

The antibiotics roseoflavin and 8-demethyl-8-amino-riboflavin from Streptomyces davawensis are metabolized by human flavokinase and human FAD synthetase

(2011) Danielle B. Pedrolli et al.   BIOCHEMICAL PHARMACOLOGY

RibM from Streptomyces davawensis is a riboflavin/roseoflavin transporter and may be useful for the optimization of riboflavin production strains

(2011) Sabrina Hemberger et al.   BMC BIOTECHNOLOGY

Flavogenomics - a genomic and structural view of flavin-dependent proteins

(2011) Peter Macheroux et al.   FEBS Journal

A NovelN,N-8-Amino-8-demethyl-d-riboflavin Dimethyltransferase (RosA) Catalyzing the Two Terminal Steps of Roseoflavin Biosynthesis inStreptomyces davawensis

(2011) Frank Jankowitsch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Riboflavin analog Roseoflavin targets an FMN-riboswitch and blocksListeria monocytogenes growth, but also stimulates virulence gene-expression and infection

(2011) Mikael Mansjö et al.   RNA Biology

The RFN riboswitch ofBacillus subtilisis a target for the antibiotic roseoflavin produced byStreptomyces davawensis

(2010) Eva Ott et al.   RNA Biology

Roseoflavin is a natural antibacterial compound that binds to FMN riboswitches and regulates gene expression

(2010) Elaine R. Lee et al.   RNA Biology

A Novel Class of Modular Transporters for Vitamins in Prokaryotes

(2008) D. A. Rodionov et al.   JOURNAL OF BACTERIOLOGY

In Vivo Generation of Flavoproteins with Modified Cofactors

(2008) Tilo Mathes et al.   JOURNAL OF MOLECULAR BIOLOGY