A highly specialized flavin mononucleotide riboswitch responds differently to similar ligands and confers roseoflavin resistance to Streptomyces davawensis

The antibiotics roseoflavin and 8-demethyl-8-amino-riboflavin from Streptomyces davawensis are metabolized by human flavokinase and human FAD synthetase

(2011) Danielle B. Pedrolli et al.   BIOCHEMICAL PHARMACOLOGY

RibM from Streptomyces davawensis is a riboflavin/roseoflavin transporter and may be useful for the optimization of riboflavin production strains

(2011) Sabrina Hemberger et al.   BMC BIOTECHNOLOGY

Flavogenomics - a genomic and structural view of flavin-dependent proteins

(2011) Peter Macheroux et al.   FEBS Journal

A NovelN,N-8-Amino-8-demethyl-d-riboflavin Dimethyltransferase (RosA) Catalyzing the Two Terminal Steps of Roseoflavin Biosynthesis inStreptomyces davawensis

(2011) Frank Jankowitsch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Riboflavin analog Roseoflavin targets an FMN-riboswitch and blocksListeria monocytogenes growth, but also stimulates virulence gene-expression and infection

(2011) Mikael Mansjö et al.   RNA Biology

The RFN riboswitch ofBacillus subtilisis a target for the antibiotic roseoflavin produced byStreptomyces davawensis

(2010) Eva Ott et al.   RNA Biology

Roseoflavin is a natural antibacterial compound that binds to FMN riboswitches and regulates gene expression

(2010) Elaine R. Lee et al.   RNA Biology

Coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch

(2009) Alexander Serganov et al.   NATURE

Rfam: updates to the RNA families database

(2008) P. P. Gardner et al.   NUCLEIC ACIDS RESEARCH