Reduced GM1 ganglioside in CFTR-deficient human airway cells results in decreased β1-integrin signaling and delayed wound repair

CFTR and GM1 “gangl-ing” up to heal thy wound. Focus on “Reduced GM1 ganglioside in CFTR-deficient human airway cells results in decreased β1-integrin signaling and delayed wound repair”

(2014) Jada C. Domingue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Gangliosides and Gangliosidoses: Principles of Molecular and Metabolic Pathogenesis

(2013) K. Sandhoff et al.   JOURNAL OF NEUROSCIENCE

Enhancement of malignant properties of human osteosarcoma cells with disialyl gangliosides GD2/GD3

(2012) Hidenobu Shibuya et al.   CANCER SCIENCE

Improvement of defective cystic fibrosis airway epithelial wound repair after CFTR rescue

(2012) Nguyen Thu Ngan Trinh et al.   EUROPEAN RESPIRATORY JOURNAL

Regulation of normal and cystic fibrosis airway epithelial repair processes by TNF-α after injury

(2011) Emilie Maillé et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Airway epithelial wounds in rhesus monkey generate ionic currents that guide cell migration to promote healing

(2011) Yao-Hui Sun et al.   JOURNAL OF APPLIED PHYSIOLOGY

The Cystic Fibrosis Transmembrane Conductance Regulator's Expanding SNARE Interactome

(2011) Bor Luen Tang et al.   TRAFFIC

CFTR channels and wound healing. Focus on “Cystic fibrosis transmembrane conductance regulator is involved in airway epithelial wound repair”

(2010) Kevin L. Kirk   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Cystic fibrosis transmembrane conductance regulator is involved in airway epithelial wound repair

(2010) Katherine R. Schiller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Update in Cystic Fibrosis 2009

(2010) Peter J. Mogayzel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ceramide Is Increased in the Lower Airway Epithelium of People with Advanced Cystic Fibrosis Lung Disease

(2010) Malcolm Brodlie et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Accumulation of ceramide in the trachea and intestine of cystic fibrosis mice causes inflammation and cell death

(2010) Katrin Anne Becker et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Protein Processing and Inflammatory Signaling in Cystic Fibrosis: Challenges and Therapeutic Strategies

(2010) C. Belcher et al.   CURRENT MOLECULAR MEDICINE

Ganglioside GD3 Enhances Adhesion Signals and Augments Malignant Properties of Melanoma Cells by Recruiting Integrins to Glycolipid-enriched Microdomains

(2010) Yuki Ohkawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alveolar inflammation in cystic fibrosis

(2010) Martina Ulrich et al.   Journal of Cystic Fibrosis

Alterations in Ceramide Concentration and pH Determine the Release of Reactive Oxygen Species by Cftr-Deficient Macrophages on Infection

(2010) Y. Zhang et al.   JOURNAL OF IMMUNOLOGY

Revitalizing membrane rafts: new tools and insights

(2010) Kai Simons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ganglioside synthase knockout in oncogene-transformed fibroblasts depletes gangliosides and impairs tumor growth

(2010) Y Liu et al.   ONCOGENE

Proinflammatory Phenotype and Increased Caveolin-1 in Alveolar Macrophages with Silenced CFTR mRNA

(2010) Yaqin Xu et al.   PLoS One

Defective organellar acidification as a cause of cystic fibrosis lung disease: reexamination of a recurring hypothesis

(2009) Peter M. Haggie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

CFTR Regulation of Intracellular pH and Ceramides Is Required for Lung Endothelial Cell Apoptosis

(2009) Julie Noe et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Acid Sphingomyelinase Inhibitors Normalize Pulmonary Ceramide and Inflammation in Cystic Fibrosis

(2009) Katrin Anne Becker et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

AsialoGM1 and integrin α2β1 mediate prostate cancer progression

(2009) Van Slambrouck   INTERNATIONAL JOURNAL OF ONCOLOGY

Defective CFTR increases synthesis and mass of sphingolipids that modulate membrane composition and lipid signaling

(2009) Hiroko Hamai et al.   JOURNAL OF LIPID RESEARCH

Gangliosides and β1-Integrin Are Required for Caveolae and Membrane Domains

(2009) Raman Deep Singh et al.   TRAFFIC

Cystic Fibrosis Fatty Acid Imbalance Is Linked to Ceramide Deficiency and Corrected by Fenretinide

(2008) Claudine Guilbault et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Hyperinflammation in airways of cystic fibrosis patients: what’s new?

(2008) Jacky Jacquot et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Immuno stimulating glycophosphosphingolipid antigen from Leishmania donovani is recognized by visceral leishmaniasis patient sera

(2008) Siddhartha Kumar Bhaumik et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis

(2008) Volker Teichgräber et al.   NATURE MEDICINE

Fenretinide Corrects Newly Found Ceramide Deficiency in Cystic Fibrosis

(2007) Claudine Guilbault et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Focal adhesion kinase as well as p130Cas and paxillin is crucially involved in the enhanced malignant properties under expression of ganglioside GD3 in melanoma cells

(2007) Kazunori Hamamura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Functional role of glycosphingolipids and gangliosides in control of cell adhesion, motility, and growth, through glycosynaptic microdomains

(2007) Adriane Regina Todeschini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS