Novel RAAS agonists and antagonists: clinical applications and controversies
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Novel RAAS agonists and antagonists: clinical applications and controversies
Authors
Keywords
-
Journal
Nature Reviews Endocrinology
Volume 11, Issue 4, Pages 242-252
Publisher
Springer Nature
Online
2015-02-10
DOI
10.1038/nrendo.2015.6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- AT 2 Receptor Activation Induces Natriuresis and Lowers Blood Pressure
- (2014) Brandon A. Kemp et al. CIRCULATION RESEARCH
- Baseline characteristics and treatment of patients in Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF)
- (2014) John J. V. McMurray et al. EUROPEAN JOURNAL OF HEART FAILURE
- Independence of the blood pressure lowering effect and efficacy of the angiotensin receptor neprilysin inhibitor, LCZ696, in patients with heart failure with preserved ejection fraction: an analysis of the PARAMOUNT trial
- (2014) Pardeep S. Jhund et al. EUROPEAN JOURNAL OF HEART FAILURE
- Aldosterone receptor blockers spironolactone and canrenone: two multivalent drugs
- (2014) Decio Armanini et al. EXPERT OPINION ON PHARMACOTHERAPY
- Angiotensin-(1–7)
- (2014) Robson Augusto Santos HYPERTENSION
- Efficacy and Safety of LCZ696, a First-in-Class Angiotensin Receptor Neprilysin Inhibitor, in Asian Patients With Hypertension
- (2014) Kazuomi Kario et al. HYPERTENSION
- Guidelines for Managing High Blood Pressure
- (2014) Wendy S. Klein et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Finerenone, a Novel Selective Nonsteroidal Mineralocorticoid Receptor Antagonist Protects From Rat Cardiorenal Injury
- (2014) Peter Kolkhof et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure
- (2014) John J.V. McMurray et al. NEW ENGLAND JOURNAL OF MEDICINE
- Direct Angiotensin AT2 Receptor Stimulation Using a Novel AT2 Receptor Agonist, Compound 21, Evokes Neuroprotection in Conscious Hypertensive Rats
- (2014) Claudia A. McCarthy et al. PLoS One
- Treatment with Angiotensin-(1–7) reduces inflammation in carotid atherosclerotic plaques
- (2014) Silvia Savergnini et al. THROMBOSIS AND HAEMOSTASIS
- Rationale and study design of the Prospective comparison of Angiotensin Receptor neprilysin inhibitor with Angiotensin receptor blocker MEasuring arterial sTiffness in the eldERly (PARAMETER) study
- (2014) Bryan Williams et al. BMJ Open
- Age and Sex Effects on the Single- and Multiple-Dose Safety and Pharmacokinetics of the New Renin Inhibitor ACT-178882
- (2013) Jasper Dingemanse et al. Cardiovascular Therapeutics
- Pharmacokinetics and Pharmacodynamics of Recombinant Human Angiotensin-Converting Enzyme 2 in Healthy Human Subjects
- (2013) Manuel Haschke et al. CLINICAL PHARMACOKINETICS
- N-acetyl-seryl-aspartyl-lysyl-proline reduces cardiac collagen cross-linking and inflammation in angiotensin II-induced hypertensive rats
- (2013) Germán E. González et al. CLINICAL SCIENCE
- Circulating Aminopeptidase Activities in Men and Women with Essential Hypertension
- (2013) R. Ortega et al. CURRENT MEDICINAL CHEMISTRY
- Safety and tolerability of the novel non-steroidal mineralocorticoid receptor antagonist BAY 94-8862 in patients with chronic heart failure and mild or moderate chronic kidney disease: a randomized, double-blind trial
- (2013) Bertram Pitt et al. EUROPEAN HEART JOURNAL
- Introduction to the revised American Association for the Study of Liver Diseases Practice Guideline management of adult patients with ascites due to cirrhosis 2012
- (2013) Bruce A. Runyon HEPATOLOGY
- MicroRNA-24 Is a Novel Regulator of Aldosterone and Cortisol Production in the Human Adrenal Cortex
- (2013) Stacy Robertson et al. HYPERTENSION
- Chronic Angiotensin II Infusion Drives Extensive Aldosterone-Independent Epithelial Na + Channel Activation
- (2013) Mykola Mamenko et al. HYPERTENSION
- An Effective Approach to High Blood Pressure Control
- (2013) Alan S. Go et al. HYPERTENSION
- LCI699, a Potent 11β-hydroxylase Inhibitor, Normalizes Urinary Cortisol in Patients With Cushing's Disease: Results From a Multicenter, Proof-of-Concept Study
- (2013) Xavier Bertagna et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Low dose spironolactone reduces blood pressure in patients with resistant hypertension and type 2 diabetes mellitus
- (2013) Christina S. Oxlund et al. JOURNAL OF HYPERTENSION
- Oral administration of angiotensin-(1–7) ameliorates type 2 diabetes in rats
- (2013) Sérgio H. S. Santos et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Combined Angiotensin Inhibition for the Treatment of Diabetic Nephropathy
- (2013) Linda F. Fried et al. NEW ENGLAND JOURNAL OF MEDICINE
- An orally active angiotensin-(1–7) inclusion compound and exercise training produce similar cardiovascular effects in spontaneously hypertensive rats
- (2013) Mariane Bertagnolli et al. PEPTIDES
- Beneficial Effects of the Activation of the Angiotensin-(1–7) Mas Receptor in a Murine Model of Adriamycin-Induced Nephropathy
- (2013) Kátia Daniela Silveira et al. PLoS One
- Construction, expression and immunogenicity of a novel anti-hypertension angiotensin II vaccine based on hepatitis A virus-like particle
- (2013) Xia Ou et al. Human Vaccines & Immunotherapeutics
- Comparative Risk for Angioedema Associated With the Use of Drugs That Target the Renin-Angiotensin-Aldosterone System
- (2012) Sengwee Toh et al. ARCHIVES OF INTERNAL MEDICINE
- Discovery of BAY 94-8862: A Nonsteroidal Antagonist of the Mineralocorticoid Receptor for the Treatment of Cardiorenal Diseases
- (2012) Lars Bärfacker et al. ChemMedChem
- AT2 receptor agonists
- (2012) Ulrike M. Steckelings et al. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
- Angiotensin-converting enzyme inhibitors reduce mortality in hypertension: a meta-analysis of randomized clinical trials of renin-angiotensin-aldosterone system inhibitors involving 158 998 patients
- (2012) L. C. van Vark et al. EUROPEAN HEART JOURNAL
- Entry-into-humans study with a new direct renin inhibitor
- (2012) Laurent B. Nicolas et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- AVE 0991, a non-peptide Mas-receptor agonist, facilitates penile erection
- (2012) Andrey C. da Costa Gonçalves et al. EXPERIMENTAL PHYSIOLOGY
- Pharmacokinetics, Pharmacodynamics, and Tolerability of ACT-077825, a New Direct Renin Inhibitor After Multiple-ascending Doses in Healthy Subjects
- (2012) Laurent B. Nicolas et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- The Effects of Aldosterone Synthase Inhibition on Aldosterone and Cortisol in Patients With Hypertension: A Phase II, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study
- (2012) Karl Andersen et al. Journal of Clinical Hypertension
- Angiotensin-converting enzyme 2, angiotensin-(1–7) and Mas: new players of the renin–angiotensin system
- (2012) Robson A S Santos et al. JOURNAL OF ENDOCRINOLOGY
- The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomised controlled trial
- (2012) Scott D Solomon et al. LANCET
- Effect of combination of renin inhibitor and Mas-receptor agonist in DOCA–salt-induced hypertension in rats
- (2012) Yogendra Singh et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Aldosterone synthase inhibition in humans
- (2012) Michel Azizi et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- AT2-receptor stimulation enhances axonal plasticity after spinal cord injury by upregulating BDNF expression
- (2012) Pawel Namsolleck et al. NEUROBIOLOGY OF DISEASE
- Cardiorenal End Points in a Trial of Aliskiren for Type 2 Diabetes
- (2012) Hans-Henrik Parving et al. NEW ENGLAND JOURNAL OF MEDICINE
- The (pro)renin receptor. A decade of research: what have we learned?
- (2012) Manne Krop et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Antihypertensive and Cardiorenal Protective Effects of SM-368229, a Novel Mineralocorticoid Receptor Antagonist, in Aldosterone/Salt-Treated Rats
- (2012) Tetsuro Nariai et al. PHARMACOLOGY
- Discovery of Inhibitors of Insulin-Regulated Aminopeptidase as Cognitive Enhancers
- (2012) Hanna Andersson et al. International Journal of Hypertension
- Renoprotective Effects of AVE0991, a Nonpeptide Mas Receptor Agonist, in Experimental Acute Renal Injury
- (2012) Lívia Corrêa Barroso et al. International Journal of Hypertension
- Renal proximal tubule angiotensin AT1A receptors regulate blood pressure
- (2011) Huiping Li et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Effects of a Novel Aldosterone Synthase Inhibitor for Treatment of Primary Hypertension
- (2011) David A. Calhoun et al. CIRCULATION
- Angiotensin Type 2 Receptor Agonist Compound 21 Reduces Vascular Injury and Myocardial Fibrosis in Stroke-Prone Spontaneously Hypertensive Rats
- (2011) Asia Rehman et al. HYPERTENSION
- SM-368229, a Novel Selective and Potent Non-steroidal Mineralocorticoid Receptor Antagonist With Strong Urinary Na+ Excretion Activity
- (2011) Tetsuro Nariai et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Role of angiotensin in ovarian follicular development and ovulation in mammals: a review of recent advances
- (2011) Paulo Bayard Gonçalves et al. REPRODUCTION
- Angiotensin-Converting Enzyme 2: The First Decade
- (2011) Nicola E. Clarke et al. International Journal of Hypertension
- N-(Pyridin-3-yl)benzamides as selective inhibitors of human aldosterone synthase (CYP11B2)
- (2010) Christina Zimmer et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Inhibition of renin–angiotensin system affects prognosis of advanced pancreatic cancer receiving gemcitabine
- (2010) Y Nakai et al. BRITISH JOURNAL OF CANCER
- Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction
- (2010) JiuChang Zhong et al. CIRCULATION
- Aldosterone Synthase Inhibition With LCI699
- (2010) Laurence Amar et al. HYPERTENSION
- Angiotensin AT 2 Receptor Stimulation Inhibits Early Renal Inflammation in Renovascular Hypertension
- (2010) Luis C. Matavelli et al. HYPERTENSION
- A New Mode of Mineralocorticoid Receptor Antagonism by a Potent and Selective Nonsteroidal Molecule
- (2010) Jérôme Fagart et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Anti-Inflammatory Effects of the Activation of the Angiotensin-(1-7) Receptor, Mas, in Experimental Models of Arthritis
- (2010) K. D. da Silveira et al. JOURNAL OF IMMUNOLOGY
- Effects of the renin inhibitor MK-8141 (ACT-077825) in patients with hypertension
- (2010) Charlotte Jones-Burton et al. Journal of the American Society of Hypertension
- Blood-pressure reduction with LCZ696, a novel dual-acting inhibitor of the angiotensin II receptor and neprilysin: a randomised, double-blind, placebo-controlled, active comparator study
- (2010) Luis Miguel Ruilope et al. LANCET
- Insulin-regulated Aminopeptidase Is a Key Regulator of GLUT4 Trafficking by Controlling the Sorting of GLUT4 from Endosomes to Specialized Insulin-regulated Vesicles
- (2010) Ingrid Jordens et al. MOLECULAR BIOLOGY OF THE CELL
- Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms
- (2010) Faiez Zannad et al. NEW ENGLAND JOURNAL OF MEDICINE
- Human Recombinant ACE2 Reduces the Progression of Diabetic Nephropathy
- (2009) G. Y. Oudit et al. DIABETES
- Regression of Left Ventricular Mass by Antihypertensive Treatment
- (2009) Robert H. Fagard et al. HYPERTENSION
- Efficacy of Spironolactone Therapy in Patients With True Resistant Hypertension
- (2009) Fabio de Souza et al. HYPERTENSION
- Inhibition of the renin–angiotensin system and target organ protection
- (2009) Jun Iwanami et al. HYPERTENSION RESEARCH
- Vaccine for hypertension: Modulating the renin–angiotensin system
- (2009) Rabindra Pandey et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Pharmacokinetics and Pharmacodynamics of LCZ696, a Novel Dual-Acting Angiotensin Receptor-Neprilysin Inhibitor (ARNi)
- (2009) Jessie Gu et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Stimulation of AT2 receptor exerts beneficial effects in stroke-prone rats: focus on renal damage
- (2009) Paolo Gelosa et al. JOURNAL OF HYPERTENSION
- Aldosterone antagonism or synthase inhibition reduces end-organ damage induced by treatment with angiotensin and high salt
- (2009) William B. Lea et al. KIDNEY INTERNATIONAL
- Angiotensin IV-evoked vasoprotection is conserved in advanced atheroma
- (2008) Antony Vinh et al. ATHEROSCLEROSIS
- Angiotensin II Type 2 Receptor Stimulation
- (2008) Elena Kaschina et al. CIRCULATION
- Aldosterone synthase inhibition improves cardiovascular function and structure in rats with heart failure: a comparison with spironolactone
- (2008) P. Mulder et al. EUROPEAN HEART JOURNAL
- Identification and characterization of a new cognitive enhancer based on inhibition of insulin-regulated aminopeptidase
- (2008) Anthony L. Albiston et al. FASEB JOURNAL
- Transgenic Angiotensin-Converting Enzyme 2 Overexpression in Vessels of SHRSP Rats Reduces Blood Pressure and Improves Endothelial Function
- (2008) Brit Rentzsch et al. HYPERTENSION
- Thrombolytics for PE and right ventricular dysfunction
- (2008) Syed Wamique Yusuf et al. LANCET
- Effect of immunisation against angiotensin II with CYT006-AngQb on ambulatory blood pressure: a double-blind, randomised, placebo-controlled phase IIa study
- (2008) Alain C Tissot et al. LANCET
- Telmisartan, Ramipril, or Both in Patients at High Risk for Vascular Events
- (2008) NEW ENGLAND JOURNAL OF MEDICINE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now