Age and Sex Effects on the Single- and Multiple-Dose Safety and Pharmacokinetics of the New Renin Inhibitor ACT-178882

The 2010 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 2 – therapy

(2011) Daniel G. Hackam et al.   CANADIAN JOURNAL OF CARDIOLOGY

Aliskiren: the first direct renin inhibitor available for clinical use

(2011) Alberto Morganti et al.   JOURNAL OF NEPHROLOGY

Prescribing for Older Adults

(2011) Manpreet K. Boparai et al.   MOUNT SINAI JOURNAL OF MEDICINE

Pharmacovigilance analysis of adverse event reports for aliskiren hemifumarate, a first-in-class direct renin inhibitor

(2011) Ayad Ali   Therapeutics and Clinical Risk Management

Piperidine-based renin inhibitors: Upper chain optimization

(2010) Olivier Corminboeuf et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Review on Pharmacokinetics and Pharmacodynamics and the Aging Kidney

(2010) C. Aymanns et al.   Clinical Journal of the American Society of Nephrology

Age-Related Pharmacokinetic and Pharmacodynamic Changes and Related Risk of Adverse Drug Reactions

(2010) A. Corsonello et al.   CURRENT MEDICINAL CHEMISTRY

Influence of Body Weight and Gender on the Pharmacokinetics, Pharmacodynamics, and Antihypertensive Efficacy of Aliskiren

(2010) Venkateswar Jarugula et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Efficacy, safety and tolerability of aliskiren, a direct renin inhibitor, in women with hypertension: a pooled analysis of eight studies

(2010) A H Gradman et al.   JOURNAL OF HUMAN HYPERTENSION

2010 ACCF/AHA Guideline for Assessment of Cardiovascular Risk in Asymptomatic Adults

(2010) Philip Greenland et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Pharmacokinetics and drug metabolism in the elderly

(2009) Ulrich Klotz   DRUG METABOLISM REVIEWS

Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Endpoints (ALTITUDE): rationale and study design

(2009) H.-H. Parving et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Prescribing for older people

(2008) James C Milton et al.   BMJ-British Medical Journal