Do genetic variations alter the effects of exercise training on cardiovascular disease and can we identify the candidate variants now or in the future?

Charting a course for genomic medicine from base pairs to bedside

(2011) Eric D. Green et al.   NATURE

Association of the 9p21.3 Locus With Risk of First-Ever Myocardial Infarction in Pakistanis

(2010) Danish Saleheen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Significance of genetic factors for the plasma insulin response to glucose in healthy subjects

(2010) Jan Lindsten et al.   CLINICAL GENETICS

The heritability of serum lipoprotein and lipid concentrations. A twin study

(2010) Arvid Heiberg   CLINICAL GENETICS

Insertion/deletion (I/D) polymorphism at the locus for angiotensin I-converting enzyme and myocardial infarction

(2010) M. Bøhn et al.   CLINICAL GENETICS

Effects of aerobic exercise on the blood pressure, oxidative stress and eNOS gene polymorphism in pre-hypertensive older people

(2010) Anderson Saranz Zago et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Women with TT genotype for eNOS gene are more responsive in lowering blood pressure in response to exercise

(2010) Carlos H.G. Sponton et al.   EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION

Genetic influence on blood pressure measured in the office, under laboratory stress and during real life

(2010) Xiaoling Wang et al.   HYPERTENSION RESEARCH

Genetic causes of high and low serum HDL-cholesterol

(2010) Daphna Weissglas-Volkov et al.   JOURNAL OF LIPID RESEARCH

Advances in Exercise, Fitness, and Performance Genomics

(2010) TUOMO RANKINEN et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

(2010) Benjamin F Voight et al.   NATURE GENETICS

Exercise training improves muscle vasodilatation in individuals with T786C polymorphism of endothelial nitric oxide synthase gene

(2010) Marcelo V. Negrao et al.   PHYSIOLOGICAL GENOMICS

Physical activity attenuates the body mass index–increasing influence of genetic variation in the FTO gene

(2009) Karani S Vimaleswaran et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Fat and carbohydrate intake modify the association between genetic variation in the FTO genotype and obesity

(2009) Emily Sonestedt et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Identification of Genetic Markers Associated With High-Density Lipoprotein-Cholesterol by Genome-Wide Screening in a Japanese Population

(2009) Yumiko Hiura et al.   CIRCULATION JOURNAL

Impact of Adding a Single Allele in the 9p21 Locus to Traditional Risk Factors on Reclassification of Coronary Heart Disease Risk and Implications for Lipid-Modifying Therapy in the Atherosclerosis Risk in Communities Study

(2009) Ariel Brautbar et al.   Circulation-Cardiovascular Genetics

Improvements in glucose homeostasis in response to regular exercise are influenced by the PPARG Pro12Ala variant: results from the HERITAGE Family Study

(2009) S.-M. Ruchat et al.   DIABETOLOGIA

Association of angiotensin-converting enzyme insertion/deletion polymorphism with obesity, cardiovascular risk factors and exercise-mediated changes in Korean women

(2009) Kijin Kim   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Variant on 9p21 strongly associates with coronary heart disease, but lacks association with common stroke

(2009) Robin Lemmens et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Genome-wide association study identifies eight loci associated with blood pressure

(2009) Christopher Newton-Cheh et al.   NATURE GENETICS

Plasma lipoproteins: genetic influences and clinical implications

(2009) Robert A. Hegele   NATURE REVIEWS GENETICS

FTO Genotype Is Associated With Exercise Training–induced Changes in Body Composition

(2009) Tuomo Rankinen et al.   Obesity

Treatment of Obese Adolescents: The Influence of Periodization Models and ACE Genotype

(2009) Denis Foschini et al.   Obesity

FTO Genotype and the Weight Loss Benefits of Moderate Intensity Exercise

(2009) Jonathan A. Mitchell et al.   Obesity

The Common Variant in theFTOGene Did Not Modify the Effect of Lifestyle Changes on Body Weight: The Finnish Diabetes Prevention Study

(2009) Tiina J. Lappalainen et al.   Obesity

Genetic Variants Associated with Complex Human Diseases Show Wide Variation across Multiple Populations

(2009) A. Adeyemo et al.   Public Health Genomics

Understanding cardiovascular disease through the lens of genome-wide association studies

(2009) Dan E. Arking et al.   TRENDS IN GENETICS

Habitual Energy Expenditure Modifies the Association Between NOS3 Gene Polymorphisms and Blood Pressure

(2008) Karani S. Vimaleswaran et al.   AMERICAN JOURNAL OF HYPERTENSION

Physical Activity and the Association of Common FTO Gene Variants With Body Mass Index and Obesity

(2008) Evadnie Rampersaud et al.   ARCHIVES OF INTERNAL MEDICINE

Heritability of cardiovascular risk factors in a Brazilian population: Baependi Heart Study

(2008) Camila M de Oliveira et al.   BMC Medical Genetics

Cardiovascular Genomics, Personalized Medicine, and the National Heart, Lung, and Blood Institute

(2008) Christopher J. O'Donnell et al.   Circulation-Cardiovascular Genetics

Assessing gene–treatment interactions at the FTO and INSIG2 loci on obesity-related traits in the Diabetes Prevention Program

(2008) P. W. Franks et al.   DIABETOLOGIA

Association of Cholesteryl Ester Transfer Protein Genotypes With CETP Mass and Activity, Lipid Levels, and Coronary Risk

(2008) Alexander Thompson   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Variations inPPARDDetermine the Change in Body Composition during Lifestyle Intervention: A Whole-Body Magnetic Resonance Study

(2008) Claus Thamer et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Human Gene Map for Performance and Health-Related Fitness Phenotypes

(2008) MOLLY S. BRAY et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Genetic Susceptibility to Type 2 Diabetes and Implications for Antidiabetic Therapy

(2007) Allan F. Moore et al.   Annual Review of Medicine