PNPLA3 Gene Polymorphism Is Associated With Predisposition to and Severity of Alcoholic Liver Disease

Systematic review with meta-analysis: the I148M variant of patatin-like phospholipase domain-containing 3 gene (PNPLA3) is significantly associated with alcoholic liver cirrhosis

(2014) A.-J. Chamorro et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

The Effect of PNPLA3 on Fibrosis Progression and Development of Hepatocellular Carcinoma: A Meta-analysis

(2014) Amit G Singal et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Association between thePNPLA3(rs738409 C>G) variant and hepatocellular carcinoma: Evidence from a meta-analysis of individual participant data

(2013) Eric Trépo et al.   HEPATOLOGY

Impact ofPNPLA3polymorphisms on the development of hepatocellular carcinoma in patients with chronic hepatitis C virus infection

(2013) Masaya Sato et al.   HEPATOLOGY RESEARCH

1404 THE PNPA3 I148M MUTATION SIGNIFICANTLY INCREASES THE RISK OF DEVELOPING ALCOHOL-RELATED CIRRHOSIS IN ALCOHOL DEPENDENT INDIVIDUALS

(2013) M.J. Way et al.   JOURNAL OF HEPATOLOGY

PNPLA3I148M (rs738409) genetic variant and age at onset of at-risk alcohol consumption are independent risk factors for alcoholic cirrhosis

(2013) Maria Antonella Burza et al.   LIVER INTERNATIONAL

712 PNPLA 3 RS738409 GG HOMOZYGOTE STATUS IS ASSOCIATED WITH INCREASED RISK OF HEPATOCELLULAR CARCINOMA IN CIRRHOTIC PATIENTS

(2012) S. Hamza et al.   JOURNAL OF HEPATOLOGY

PNPLA3 rs738409, hepatocellular carcinoma occurrence and risk model prediction in patients with cirrhosis

(2012) Erwan Guyot et al.   JOURNAL OF HEPATOLOGY

A Common Variant of PNPLA3 (p.I148M) Is Not Associated with Alcoholic Chronic Pancreatitis

(2012) Jonas Rosendahl et al.   PLoS One

Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets

(2011) Bin Gao et al.   GASTROENTEROLOGY

PNPLA3(rs738409 C>G) is a common risk variant associated with hepatocellular carcinoma in alcoholic cirrhosis

(2011) Eric Trepo et al.   HEPATOLOGY

Common polymorphism in the PNPLA3/adiponutrin gene confers higher risk of cirrhosis and liver damage in alcoholic liver disease

(2011) Eric Trépo et al.   JOURNAL OF HEPATOLOGY

PNPLA3 rs738409C/G polymorphism in cirrhosis: relationship with the aetiology of liver disease and hepatocellular carcinoma occurrence

(2011) Edmondo Falleti et al.   LIVER INTERNATIONAL

The PNPLA3 rs738409 148M/M Genotype Is a Risk Factor for Liver Cancer in Alcoholic Cirrhosis but Shows No or Weak Association in Hepatitis C Cirrhosis

(2011) Hans Dieter Nischalke et al.   PLoS One

Patatin-like phospholipase domain containing 3: A case in point linking genetic susceptibility for alcoholic and nonalcoholic liver disease

(2010) Devanshi Seth et al.   HEPATOLOGY

Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians

(2010) Felix Stickel et al.   HEPATOLOGY

Hardy-Weinberg Equilibrium Testing of Biological Ascertainment for Mendelian Randomization Studies

(2009) Santiago Rodriguez et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Dissociation Between Fatty Liver and Insulin Resistance in Humans Carrying a Variant of the Patatin-Like Phospholipase 3 Gene

(2009) K. Kantartzis et al.   DIABETES

A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

(2009) A. Kotronen et al.   DIABETOLOGIA

Prediction of Non-Alcoholic Fatty Liver Disease and Liver Fat Using Metabolic and Genetic Factors

(2009) Anna Kotronen et al.   GASTROENTEROLOGY

Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent

(2009) S Romeo et al.   INTERNATIONAL JOURNAL OF OBESITY

A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity

(2009) Silvia Sookoian et al.   JOURNAL OF LIPID RESEARCH

A common variant in the adiponutrin gene influences liver enzyme values

(2009) B. Kollerits et al.   JOURNAL OF MEDICAL GENETICS

Variant in PNPLA3 is associated with alcoholic liver disease

(2009) Chao Tian et al.   NATURE GENETICS

Risk Factors for Chronic Liver Disease in Blacks, Mexican Americans, and Whites in the United States: Results From NHANES IV, 1999-2004

(2008) Yvonne N. Flores et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Population-Based Genome-wide Association Studies Reveal Six Loci Influencing Plasma Levels of Liver Enzymes

(2008) Xin Yuan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS