Structure of the voltage-gated two-pore channel TPC1 from Arabidopsis thaliana

Lysosomal Physiology

(2015) Haoxing Xu et al.   Annual Review of Physiology

Expression of Ca2+-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells

(2015) M. Ruas et al.   EMBO JOURNAL

Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment

(2015) Yasuteru Sakurai et al.   SCIENCE

Convergent regulation of the lysosomal two-pore channel-2 by Mg2+, NAADP, PI(3,5)P2 and multiple protein kinases

(2014) A. Jha et al.   EMBO JOURNAL

The voltage-gated sodium channel TPC1 confers endolysosomal excitability

(2014) Chunlei Cang et al.   Nature Chemical Biology

Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain

(2014) Qufei Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

X-ray crystal structure of voltage-gated proton channel

(2014) Kohei Takeshita et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Salt stress-induced Ca2+ waves are associated with rapid, long-distance root-to-shoot signaling in plants

(2014) W.-G. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two-pore channels provide insight into the evolution of voltage-gated Ca2+ and Na+ channels

(2014) T. Rahman et al.   Science Signaling

Reconstituted Human TPC1 Is a Proton-Permeable Ion Channel and Is Activated by NAADP or Ca2+

(2014) S. J. Pitt et al.   Science Signaling

mTOR Regulates Lysosomal ATP-Sensitive Two-Pore Na+ Channels to Adapt to Metabolic State

(2013) Chunlei Cang et al.   CELL

TPC Proteins Are Phosphoinositide- Activated Sodium-Selective Ion Channels in Endosomes and Lysosomes

(2012) Xiang Wang et al.   CELL

China must provide education on HIV

(2012) Jian Zhang et al.   NATURE

An N-Terminal Dileucine Motif Directs Two-Pore Channels to the Tonoplast of Plant Cells

(2012) Nina Larisch et al.   TRAFFIC

TPC1 – SV Channels Gain Shape

(2011) Rainer Hedrich et al.   Molecular Plant

The crystal structure of a voltage-gated sodium channel

(2011) Jian Payandeh et al.   NATURE

A Novel Calcium Binding Site in the Slow Vacuolar Cation Channel TPC1 Senses Luminal Calcium Levels

(2011) B. Dadacz-Narloch et al.   PLANT CELL

Differential contribution of EF-hands to the Ca2+-dependent activation in the plant two-pore channel TPC1

(2011) Christina Schulze et al.   PLANT JOURNAL

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A Shaker K+ Channel with a Miniature Engineered Voltage Sensor

(2010) Yanping Xu et al.   CELL

310helices in channels and other membrane proteins

(2010) Ricardo Simão Vieira-Pires et al.   JOURNAL OF GENERAL PHYSIOLOGY

A Gating Charge Transfer Center in Voltage Sensors

(2010) X. Tao et al.   SCIENCE

Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling

(2009) Eugen Brailoiu et al.   JOURNAL OF CELL BIOLOGY

NAADP mobilizes calcium from acidic organelles through two-pore channels

(2009) Peter J. Calcraft et al.   NATURE

The two-pore channel TPCN2 mediates NAADP-dependent Ca2+-release from lysosomal stores

(2009) Xiangang Zong et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel

(2008) G. M. Clayton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA