The voltage-gated sodium channel TPC1 confers endolysosomal excitability

Convergent regulation of the lysosomal two-pore channel-2 by Mg2+, NAADP, PI(3,5)P2 and multiple protein kinases

(2014) A. Jha et al.   EMBO JOURNAL

mTOR Regulates Lysosomal ATP-Sensitive Two-Pore Na+ Channels to Adapt to Metabolic State

(2013) Chunlei Cang et al.   CELL

Chloride in Vesicular Trafficking and Function

(2012) Tobias Stauber et al.   Annual Review of Physiology

TPC Proteins Are Phosphoinositide- Activated Sodium-Selective Ion Channels in Endosomes and Lysosomes

(2012) Xiang Wang et al.   CELL

Membrane Potential Regulates Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Dependence of the pH- and Ca2+-sensitive Organellar Two-pore Channel TPC1

(2012) Volodymyr Rybalchenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Voltage-gated sodium channels at 60: structure, function and pathophysiology

(2012) William A. Catterall   JOURNAL OF PHYSIOLOGY-LONDON

Lysosomal Acidification Mechanisms

(2011) Joseph A. Mindell   Annual Review of Physiology

Molecular mechanisms of endolysosomal Ca2+signalling in health and disease

(2011) Anthony J. Morgan et al.   BIOCHEMICAL JOURNAL

ClC-7 is a slowly voltage-gated 2Cl−/1H+-exchanger and requires Ostm1 for transport activity

(2011) Lilia Leisle et al.   EMBO JOURNAL

Photoaffinity Labeling of Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Targets in Mammalian Cells

(2011) Yaping Lin-Moshier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Photoaffinity Labeling of High Affinity Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)-Binding Proteins in Sea Urchin Egg

(2011) Timothy F. Walseth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sodium Leak Channels in Neuronal Excitability and Rhythmic Behaviors

(2011) Dejian Ren   NEURON

Voltage-Gated Calcium Channels

(2011) W. A. Catterall   Cold Spring Harbor Perspectives in Biology

Characterization of Two-pore Channel 2 (TPCN2)-mediated Ca2+Currents in Isolated Lysosomes

(2010) Michael Schieder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Degeneration of an Intracellular Ion Channel in the Primate Lineage by Relaxation of Selective Constraints

(2010) X. Cai et al.   MOLECULAR BIOLOGY AND EVOLUTION

Planar Patch Clamp Approach to Characterize Ionic Currents from Intact Lysosomes

(2010) M. Schieder et al.   Science Signaling

NAADP Receptors

(2010) A. Galione   Cold Spring Harbor Perspectives in Biology

Calcium signaling via two-pore channels: local or global, that is the question

(2009) Michael X. Zhu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Defective organellar acidification as a cause of cystic fibrosis lung disease: reexamination of a recurring hypothesis

(2009) Peter M. Haggie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling

(2009) Eugen Brailoiu et al.   JOURNAL OF CELL BIOLOGY

NAADP mobilizes calcium from acidic organelles through two-pore channels

(2009) Peter J. Calcraft et al.   NATURE

The two-pore channel TPCN2 mediates NAADP-dependent Ca2+-release from lysosomal stores

(2009) Xiangang Zong et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

PIP2 Is a Necessary Cofactor for Ion Channel Function: How and Why?

(2008) Byung-Chang Suh et al.   Annual Review of Biophysics

The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel

(2008) Xian-Ping Dong et al.   NATURE

How membrane proteins sense voltage

(2008) Francisco Bezanilla   NATURE REVIEWS MOLECULAR CELL BIOLOGY