Review
Plant Sciences
Zige Yang, Pengfei Zhi, Cheng Chang
Summary: Plants have evolved adaptive strategies to cope with pathogen infections, including establishing immune memory to enhance their responsiveness to pathogens. Seed priming, as an environmentally-friendly crop protection technique, can effectively induce plant immune memory and enhance disease resistance in crops.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Food Science & Technology
Anezka Adamcova, Kristian Holst Laursen, Nicolai Zederkopff Ballin
Summary: The study determined the activity of lectins in different plant families and the effect of soaking and boiling on lectin levels, revealing that lectins from the Fabaceae family had the highest activity. This study is the first to combine lectin activity from raw and processed edible plants, emphasizing the importance of further research in this area and the development of harmonized methods for analysis and interpretation.
Review
Biotechnology & Applied Microbiology
Jianzhong Hu, Jing Cai, Tao Xu, Hunseung Kang
Summary: This article reviews the recent research progress on mRNA modifications, particularly m(6)A modifications, and summarizes their dynamics, distribution, regulation, and biological functions in plant stress responses. In addition, potential strategies for breeding stress-tolerant crops by engineering mRNA modifications are proposed, and the future direction of RNA modification research is suggested to gain a deeper understanding of plant stress biology.
PLANT BIOTECHNOLOGY JOURNAL
(2022)
Review
Chemistry, Medicinal
Jilan A. Nazeam, Abdel Nasser B. Singab
Summary: The COVID-19 pandemic has highlighted the urgent need for more cost-effective vaccines to address antibiotic resistance threats. Vaccine adjuvants play a crucial role in enhancing the effectiveness of vaccines, but the toxicity and adverse reactions of current adjuvant formulations are major issues. This review focuses on preclinical studies of immunoadjuvant plant proteins and outlines potential candidates for developing new generations of vaccine adjuvants.
PHYTOTHERAPY RESEARCH
(2022)
Review
Agriculture, Multidisciplinary
Jens Frackenpohl, Steven A. G. Abel, Neanne Alnafta, David M. Barber, Guido Bojack, Nicola Z. Brant, Hendrik Helmke, Rebecca L. Mattison
Summary: Chemical concepts such as isosteres and scaffold hopping have been proven to be powerful tools in agrochemical innovation processes. They allow for the modification of known molecular lead structures to improve various parameters in plant-hormone chemistry. Recent insights into plant-specific receptors and signaling pathways have triggered the discovery of new lead structures, leading to diverse chemical innovation and increased biological activity.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Review
Horticulture
Domenico Prisa, Damiano Spagnuolo
Summary: To ensure food security in the face of climate change, it is crucial to improve the quality and quantity of crops. Developing a sustainable bio-based economy through circular economy and biorefinery approaches can help achieve this goal. Plant biostimulants, particularly those derived from macroalgae, have been extensively explored, but research on microalgal biostimulants has been limited due to high production costs. This review provides an overview of the potential of microalgal biostimulants in enhancing crop production and quality, discussing their effects, feasibility of co-cultures and co-application with other biostimulants and biofertilisers, as well as extraction techniques and application timings.
Review
Environmental Sciences
Kishore Kumar Krishnani, Veera Mallu Boddu, Narinder Kumar Chadha, Puja Chakraborty, Jitendra Kumar, Gopal Krishna, Himanshu Pathak
Summary: Global agriculture is facing significant challenges due to climate change, including abiotic and biotic stresses caused by temperature extremes, drought, flooding, and pathogens. It is crucial to develop environmentally viable and cost-effective green processes, specifically utilizing nanomaterials, to alleviate these stresses.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Review
Biotechnology & Applied Microbiology
Leandro Pereira-Dias, Paulo R. Oliveira-Pinto, Juliana O. Fernandes, Laura Regalado, Rafael Mendes, Catia Teixeira, Nuno Mariz-Ponte, Paula Gomes, Conceicao Santos
Summary: Agricultural systems require low-cost, safe antibiotics to protect crops from pests and diseases. Peptaibiotics have shown potential as alternatives to agrochemicals, with antibacterial, antifungal, and antiviral activity, and the ability to induce plant resistance against phytopathogens. However, their low solubility and difficulty in synthesis and purification have limited their application in agriculture. This review provides a comprehensive analysis of peptaibiotics, including their classification, biosynthesis, relevance to plant protection, and mode of action against phytopathogens, as well as strategies to enhance their solubility and production.
BIOTECHNOLOGY ADVANCES
(2023)
Article
Agronomy
Prafull Salvi, Gulshan Kumar, Nishu Gandass, Kajal, Ashish Verma, Sivasubramanian Rajarammohan, Nilesh Rai, Vibhav Gautam
Summary: Essential oils from medicinal and aromatic plants exhibit antimicrobial and antifungal activities, which are correlated with their antioxidant activity. The presence of specific phytoconstituents in the essential oils may be responsible for their bioactivity, as observed through biochemical analysis and in-silico evaluation.
Article
Plant Sciences
Lin Yao, Guanghua Zhang, Lili Yu, Shaojing Liu, Xiaoku Wang, Tao Fan, Hui Kang, Wenzhi Feng
Summary: In this study, a series of 1,3,4-oxadiazole derivatives were designed and synthesized, and their antifungal activities against maize disease pathogens were evaluated. The synthesized derivatives showed strong antifungal activities, especially against E. turcicum. Some compounds induced significant shrinkage and collapse of E. turcicum hyphae. Furthermore, these compounds with antifungal activities exhibited almost no cytotoxicity to MCF-7 cells. The 1,3,4-oxadiazole derivatives have the potential to be used as antifungal agents for the control of maize diseases.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Carolina Santos, Manoela de Araujo Goncalves, Larissa Ferreira de Macedo, Andre Henrique Furtado Torres, Gabriel Davi Marena, Marlus Chorilli, Eliane Trovatti
Summary: This work presents the development of a nanoscale system using alginate to encapsulate a blend of oils that have antibacterial and antioxidant activities. The study investigates the effects of polymer and surfactant concentrations on the physicochemical properties of the nanoparticles. The results show that the nanostructured system is stable, has high encapsulation efficiency, and nanoparticles with sizes ranging from 200-400 nm.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Plant Sciences
Jie Tang, Diane C. Bassham
Summary: Drought poses a major challenge for agricultural production, but autophagy plays a crucial role in helping plants survive drought stress by regulating water permeability, degrading toxic proteins, and promoting stress responses. The activation of autophagy through transcriptional and post-translational mechanisms may offer promising strategies for enhancing drought tolerance in plants.
Article
Biochemistry & Molecular Biology
Nathan Noel, Simon Duchateau, Gatien Messire, Fabien Massicot, Jean-Luc Vasse, Sandra Villaume, Aziz Aziz, Stephan Dorey, Jerome Crouzet, Jean-Bernard Behr
Summary: A straightforward method for synthesizing carbohydrate templated isoxazolidines using microwave activation is described. The reaction involves the interaction of unprotected glycosylhydroxylamines with methyl acrylate, resulting in the formation of rhamno- and erythro-isoxazolidines. These compounds are recognized by plant cells, triggering a strong immune response and exhibiting high antifungal activity against Botrytis cinerea.
BIOORGANIC CHEMISTRY
(2023)
Article
Plant Sciences
Ying-Yu Liao, Jorge Pereira, Ziyang Huang, Qiurong Fan, Swadeshmukul Santra, Jason C. White, Roberto De la Torre-roche, Susannah Da Silva, Gary E. Vallad, Joshua H. Freeman, Jeffrey B. Jones, Mathews L. Paret
Summary: Bacterial spot of tomato is a significant disease affecting tomato plants. Previous research has shown that non-formulated magnesium oxide nanoparticles can reduce disease severity. However, the aggregation of the nanoparticles makes it difficult to use in field applications. Therefore, novel MgO and MgOH2 nanomaterials were formulated and their characteristics and disease reduction abilities were evaluated. Among the nanomaterials, SgMc showed the highest efficacy in vitro and in greenhouse experiments. However, its effectiveness was inconsistent in field conditions. Further research is needed to determine the specific variables that affect its performance in different environments.
Article
Plant Sciences
Garima Pal, Devashish Mehta, Saurabh Singh, Kalai Magal, Siddhi Gupta, Gopaljee Jha, Avinash Bajaj, Vemanna S. Ramu
Summary: The study demonstrates the antimicrobial efficacy of Cholic Acid-Glycine Conjugates (CAGCs) against Xanthomonas Oryzae pv. oryzae (Xoo) and Rhizoctonia solani (R. solani) in rice. CAGC C6 is shown to be a broad-spectrum antimicrobial that can degrade biofilms, with minimal impact on plant growth. Exogenous application of C6 can reduce bacterial load and induce plant defense responses, while priming seeds with C6 enhances plant resistance.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Yaremis Merino-Cabrera, Tiago A. de Oliveira Mendes, Jose G. S. Castro, Samuel L. Barbosa, Maria L. R. Macedo, Maria G. de Almeida Oliveira
ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY
(2020)
Article
Biochemistry & Molecular Biology
Carolina Turatti Oliveira, Suzy Wider Machado, Cezar da Silva Bezerra, Marlon Henrique Cardoso, Octavio Luiz Franco, Carlos Peres Silva, Demetrio Gomes Alves, Cristina Rios, Maria Ligia R. Macedo
Article
Cell Biology
Tamaeh Monteiro-Alfredo, Paulo Matafome, Bianca Pancoti Iacia, Katia Avila Antunes, Jessica Maurino dos Santos, Janielle da Silva Melo da Cunha, Sara Oliveira, Alex Santos Oliveira, Jaqueline Ferreira Campos, Mariana Magalhaes, Celia Cabral, Raquel Seica, Claudia Andrea Lima Cardoso, Caio Fernando Ramalho de Oliveira, Edson Lucas dos Santos, Kely de Picoli Souza
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
(2020)
Article
Biotechnology & Applied Microbiology
Amanda Carolina Borges da Silva, Janaina de Cassia Orlandi Sardi, Daniella Gorete Lourenco de Oliveira, Caio Fernando Ramalho de Oliveira, Helder Freitas dos Santos, Edson Lucas dos Santos, Edson Crusca Jr, Marlon Henrique Cardoso, Octavio Luiz Franco, Maria Ligia Rodrigues Macedo
Article
Biochemistry & Molecular Biology
Luis Henrique de Oliveira Almeida, Caio Fernando Ramalh de Oliveira, Mayara de Souza Rodrigues, Simone Maria Neto, Ana Paula de Araujo Boleti, Gabriel Bonan Taveira, Erica de Oliveira Mello, Valdirene Moreira Gomes, Edson Luca dos Santos, Edson Crusca Jr, Octavio Luiz Franco, Marlon Henrique e Silva Cardoso, Maria Ligia Rodrigues Macedo
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
(2020)
Article
Food Science & Technology
Ellynes Nunes, Breno Frihling, Elizangela Barros, Caio de Oliveira, Newton Verbisck, Taylla Flores, Augusto de Freitas Junior, Octavio Franco, Maria de Macedo, Ludovico Migliolo, Karla Luna
Article
Multidisciplinary Sciences
Kellen Natalice Vilharva, Daniel Ferreira Leite, Helder Freitas dos Santos, Katia Avila Antunes, Paola dos Santos da Rocha, Jaqueline Ferreira Campos, Claudiane Vilharroel Almeida, Maria Ligia Rodrigues Macedo, Denise Brentan Silva, Caio Fernando Ramalho de Oliveira, Edson Lucas dos Santos, Kely de Picoli Souza
Summary: Zootherapy is a traditional secular practice among the Guarani-Kaiowa indigenous ethnic group in Brazil, who use oil extracted from larvae of the snout beetle Rhynchophorus palmarum for treating skin wounds and respiratory diseases. Research has shown that the oil possesses antioxidant, antimicrobial, and healing properties, promotes cell migration, and is non-toxic in in vitro and in vivo models.
Article
Chemistry, Medicinal
Breno Emanuel Farias Frihling, Ana Paula de Araujo Boleti, Caio Fernando Ramalho de Oliveira, Simone Camargo Sanches, Pedro Henrique de Oliveira Cardoso, Newton Verbisck, Maria Ligia Rodrigues Macedo, Paula Helena Santa Rita, Cristiano Marcelo Espinola Carvalho, Ludovico Migliolo
Summary: In this study, a new acidic phospholipase with antitumor activity was identified from Bothrops moojeni venom. The enzyme showed selectivity towards colorectal adenocarcinoma cells and could be a potential candidate for the development of new biotechnological tools.
Article
Food Science & Technology
Pedro Henrique de Oliveira Cardoso, Ana Paula de Araujo Boleti, Patricia Souza E. Silva, Lincoln Takashi Hota Mukoyama, Alexya Sandim Guindo, Luiz Filipe Ramalho Nunes de Moraes, Caio Fernando Ramalho de Oliveira, Maria Ligia Rodrigues Macedo, Cristiano Marcelo Espinola Carvalho, Alinne Pereira de Castro, Ludovico Migliolo
Summary: The importance of neuroinflammation is increasingly recognized in neurological disorders, including both inflammatory diseases like multiple sclerosis and non-inflammatory conditions such as stroke, epilepsy, and cancer. A peptide called Ca-MAP1, inspired by a toxin from C. albicans, has shown promising anti-neuroinflammatory, antibacterial, and cytotoxic activity. In vitro and in silico studies demonstrated its effectiveness at lower concentrations, with low toxicity to normal cells. Ca-MAP1 also exhibited activity against various bacteria and demonstrated anti-neuroinflammatory effects. This peptide holds potential for controlling infections and serving as an alternative therapy for cancer.
Article
Food Science & Technology
Patricia Souza e Silva, Alexya Sandim Guindo, Pedro Henrique Cardoso Oliveira, Luiz Filipe Ramalho Nunes de Moraes, Ana Paula de Araujo Boleti, Marcos Antonio Ferreira, Caio Fernando Ramalho de Oliveira, Maria Ligia Rodrigues Macedo, Luana Rossato, Simone Simionatto, Ludovico Migliolo
Summary: Antimicrobial peptides derived from amphibian toxins have emerged as promising multifunctional drugs with the ability to interact with various molecular targets. In this study, we designed a novel peptide based on temporin-PTa, which exhibited antimicrobial, biofilm eradication, and antitumor activities. The peptide also showed potential as a structural model for the development of new multifunctional molecules.
Review
Biochemistry & Molecular Biology
Tamaeh Monteiro-Alfredo, Maria Ligia Rodrigues Macedo, Kely de Picoli Souza, Paulo Matafome
Summary: Brazil's Cerrado biome is rich in biodiversity and contains plants with therapeutic potential against obesity and metabolic conditions. These plants have been shown to reduce inflammation and oxidative stress, and could be used in the treatment of conditions such as obesity and type 2 diabetes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
