Synthesis and Evaluation of Paeonol Derivatives as Potential Multifunctional Agents for the Treatment of Alzheimer’s Disease

The Multifactorial Nature of Alzheimer's Disease for Developing Potential Therapeutics

(2014) M. Carreiras et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Multifunctional Tacrine Derivatives in Alzheimer’s Disease

(2014) Anna Minarini et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Design, synthesis and evaluation of genistein-O-alkylbenzylamines as potential multifunctional agents for the treatment of Alzheimer's disease

(2014) Xiaoming Qiang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and evaluation of 7,8-dehydrorutaecarpine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease

(2013) Yan He et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, and Evaluation of Multitarget-Directed Resveratrol Derivatives for the Treatment of Alzheimer’s Disease

(2013) Chuanjun Lu et al.   JOURNAL OF MEDICINAL CHEMISTRY

O-Hydroxyl- or o-amino benzylamine-tacrine hybrids: Multifunctional biometals chelators, antioxidants, and inhibitors of cholinesterase activity and amyloid-β aggregation

(2012) Fei Mao et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Effect of Paeonol on Antioxidant and Immune Regulatory Activity in Hepatocellular Carcinoma Rats

(2012) Bendong Chen et al.   MOLECULES

Paeonol increases levels of cortical cytochrome oxidase and vascular actin and improves behavior in a rat model of Alzheimer's disease

(2011) Jun Zhou et al.   BRAIN RESEARCH

Exploration of (S)-3-aminopyrrolidine as a potentially interesting scaffold for discovery of novel Abl and PI3K dual inhibitors

(2011) Cunlong Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Efficacy of memantine in delaying clinical worsening in Alzheimer's disease (AD): responder analyses of nine clinical trials with patients with moderate to severe AD

(2011) Rainer Hellweg et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease

(2011) Rafael León et al.   MEDICINAL RESEARCH REVIEWS

Synthesis, Characterization, Acetylcholinesterase Inhibition, Molecular Modeling and Antioxidant Activities of Some Novel Schiff Bases Derived from 1-(2-Ketoiminoethyl)piperazines

(2011) Saleh M. Salga et al.   MOLECULES

Paeonol Prevents Excitotoxicity in Rat Pheochromocytoma PC12 Cells via Downregulation of ERK Activation and Inhibition of Apoptosis

(2011) Xuncui Wang et al.   PLANTA MEDICA

Paeonol Attenuates Microglia-Mediated Inflammation and Oxidative Stress–Induced Neurotoxicity in Rat Primary Microglia and Cortical Neurons

(2011) Yu-Ting Tseng et al.   SHOCK

Neuroprotective therapeutics for Alzheimer's disease: progress and prospects

(2011) Alan M. Palmer   TRENDS IN PHARMACOLOGICAL SCIENCES

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cholinesterase Inhibitors and Beyond

(2009) Giancarlo Pepeu et al.   Current Alzheimer Research

Multi-target-Directed Ligands To Combat Neurodegenerative Diseases

(2008) Andrea Cavalli et al.   JOURNAL OF MEDICINAL CHEMISTRY

Paeonol attenuates neurotoxicity and ameliorates cognitive impairment induced by d-galactose in ICR mice

(2008) Shu-Zhi Zhong et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES