α-Linolenic Acid, A Nutraceutical with Pleiotropic Properties That Targets Endogenous Neuroprotective Pathways to Protect against Organophosphate Nerve Agent-Induced Neuropathology

Alpha-Linolenic Acid-Induced Increase in Neurogenesis is a Key Factor in the Improvement in the Passive Avoidance Task After Soman Exposure

(2015) Tetsade CB Piermartiri et al.   NEUROMOLECULAR MEDICINE

Administration of nicotinic receptor antagonists during the period of memory consolidation affects passive avoidance learning and modulates synaptic efficiency in the CA1 region in vivo

(2015) Y.V. Dobryakova et al.   NEUROSCIENCE

Neuroprotective and anti-inflammatory properties of a novel non-thiazolidinedione PPARγ agonist in vitro and in MPTP-treated mice

(2015) D. Lecca et al.   NEUROSCIENCE

Repeated systemic administration of the nutraceutical alpha-linolenic acid exerts neuroprotective efficacy, an antidepressant effect and improves cognitive performance when given after soman exposure

(2015) Hongna Pan et al.   NEUROTOXICOLOGY

Regulation of mTORC1 by PI3K signaling

(2015) Christian C. Dibble et al.   TRENDS IN CELL BIOLOGY

PPARβ/δ and PPARγ maintain undifferentiated phenotypes of mouse adult neural precursor cells from the subventricular zone

(2015) Carolina Bernal et al.   Frontiers in Cellular Neuroscience

Alpha-Linolenic Acid: An Omega-3 Fatty Acid with Neuroprotective Properties—Ready for Use in the Stroke Clinic?

(2015) Nicolas Blondeau et al.   Biomed Research International

DNA Methylation Perturbations in Genes Involved in Polyunsaturated Fatty Acid Biosynthesis Associated with Depression and Suicide Risk

(2015) Fatemeh Haghighi et al.   Frontiers in Neurology

Pesticide Exposure and Depression among Male Private Pesticide Applicators in the Agricultural Health Study

(2014) John D. Beard et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

α-Linolenic acid: Nutraceutical, pharmacological and toxicological evaluation

(2014) Kyu-Bong Kim et al.   FOOD AND CHEMICAL TOXICOLOGY

Adult newborn neurons are involved in learning acquisition and long-term memory formation: The distinct demands on temporal neurogenesis of different cognitive tasks

(2014) Irene Suárez-Pereira et al.   HIPPOCAMPUS

PI3K-p110-alpha-subtype signalling mediates survival, proliferation and neurogenesis of cortical progenitor cells via activation of mTORC2

(2014) Shalaka Dhanraj Wahane et al.   JOURNAL OF NEUROCHEMISTRY

Extrasynaptic NMDA Receptor Involvement in Central Nervous System Disorders

(2014) Matthew P. Parsons et al.   NEURON

The recovery of acetylcholinesterase activity and the progression of neuropathological and pathophysiological alterations in the rat basolateral amygdala after soman-induced status epilepticus: Relation to anxiety-like behavior

(2014) Eric M. Prager et al.   NEUROPHARMACOLOGY

Effects of low-level sarin and cyclosarin exposure on hippocampal subfields in Gulf War Veterans

(2014) Linda L. Chao et al.   NEUROTOXICOLOGY

Loss of Hippocampal Neurons after Kainate Treatment Correlates with Behavioral Deficits

(2014) Gisela H. Maia et al.   PLoS One

Hippocampal Neurogenesis Regulates Forgetting During Adulthood and Infancy

(2014) K. G. Akers et al.   SCIENCE

Mice with altered BDNF signaling as models for mood disorders and antidepressant effects

(2014) Jesse S. O. Lindholm et al.   Frontiers in Behavioral Neuroscience

n-3 Fatty Acids: Role in Neurogenesis and Neuroplasticity

(2013) R. Crupi et al.   CURRENT MEDICINAL CHEMISTRY

Valnoctamide andsec-butyl-propylacetamide (SPD) for acute seizures and status epilepticus

(2013) Tawfeeq Shekh-Ahmad et al.   EPILEPSIA

Effects of allantoin on cognitive function and hippocampal neurogenesis

(2013) Young Je Ahn et al.   FOOD AND CHEMICAL TOXICOLOGY

Human Studies Using Isotope Labeled Fatty Acids: Answered and Unanswered Questions

(2013) Edward Emken   Journal of Oleo Science

Syrian gas attack reinforces need for better anti-sarin drugs

(2013) Elie Dolgin   NATURE MEDICINE

Acetylcholinesterase inhibition in the basolateral amygdala plays a key role in the induction of status epilepticus after soman exposure

(2013) Eric M. Prager et al.   NEUROTOXICOLOGY

Two medical therapies very effective shortly after high levels of soman poisoning in rats, but only one with universal utility

(2013) Trond Myhrer et al.   TOXICOLOGY

Structural analogs of huperzine A improve survival in guinea pigs exposed to soman

(2012) Hendra Gunosewoyo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Baicalein attenuates impaired hippocampal neurogenesis and the neurocognitive deficits induced by γ-ray radiation

(2012) Shin Bi Oh et al.   BRITISH JOURNAL OF PHARMACOLOGY

One-step labeling of degenerative neurons in unfixed brain tissue samples using Fluoro-Jade C

(2012) Qiang Gu et al.   JOURNAL OF NEUROSCIENCE METHODS

Mechanisms of Action of (n-3) Fatty Acids

(2012) Philip C. Calder   JOURNAL OF NUTRITION

Vascular endothelial growth factor regulates adult hippocampal cell proliferation through MEK/ERK- and PI3K/Akt-dependent signaling

(2012) Neil M. Fournier et al.   NEUROPHARMACOLOGY

Alpha-linolenic acid is a potent neuroprotective agent against soman-induced neuropathology

(2012) Hongna Pan et al.   NEUROTOXICOLOGY

Combined diazepam and HDAC inhibitor treatment protects against seizures and neuronal damage caused by soman exposure

(2012) Franco Rossetti et al.   NEUROTOXICOLOGY

Effects of Sun Ginseng on Memory Enhancement and Hippocampal Neurogenesis

(2012) Chang Hwan Lee et al.   PHYTOTHERAPY RESEARCH

Reduced phosphorylation of the mTOR signaling pathway components in the amygdala of rats exposed to chronic stress

(2012) Agata Chandran et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Dietary intake of n−3 and n−6 fatty acids and the risk of clinical depression in women: a 10-y prospective follow-up study

(2011) Michel Lucas et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The role of neurotensin in passive avoidance learning in the rat central nucleus of amygdala

(2011) Kristóf László et al.   BEHAVIOURAL BRAIN RESEARCH

Biochemical responses to dietary α-linolenic acid restriction proceed differently among brain regions in mice

(2011) Daisuke Miyazawa et al.   BIOMEDICAL RESEARCH-TOKYO

Immunomodulation by poly-YE reduces organophosphate-induced brain damage

(2011) Arseny Finkelstein et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuroprotective efficacy of caramiphen against soman and mechanisms of its action

(2011) TH Figueiredo et al.   BRITISH JOURNAL OF PHARMACOLOGY

A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage

(2011) H. Steve White et al.   EPILEPSIA

CREB in adult neurogenesis - master and partner in the development of adult-born neurons?

(2011) Katharina Merz et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

4- to 6-week-old adult-born hippocampal neurons influence novelty-evoked exploration and contextual fear conditioning

(2011) Christine A. Denny et al.   HIPPOCAMPUS

The memory-enhancing effects of Kami-ondam-tang in mice

(2011) Jin Gyu Hong et al.   JOURNAL OF ETHNOPHARMACOLOGY

A Requirement for Nuclear Factor- B in Developmental and Plasticity-Associated Synaptogenesis

(2011) M. C. H. Boersma et al.   JOURNAL OF NEUROSCIENCE

Activation of cannabinoid CB1 receptors in the central amygdala impairs inhibitory avoidance memory consolidation via NMDA receptors

(2011) Maryam Ghiasvand et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

The neurogenesis hypothesis of affective and anxiety disorders: Are we mistaking the scaffolding for the building?

(2011) David Petrik et al.   NEUROPHARMACOLOGY

Diet composition exacerbates or attenuates soman toxicity in rats: Implied metabolic control of nerve agent toxicity

(2011) Todd M. Myers et al.   NEUROTOXICOLOGY

Effects of low-level sarin and cyclosarin exposure and Gulf War Illness on Brain Structure and Function: A study at 4T

(2011) Linda L. Chao et al.   NEUROTOXICOLOGY

Characterizing the behavioral effects of nerve agent-induced seizure activity in rats: Increased startle reactivity and perseverative behavior

(2011) Jeffrey L. Langston et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Mitochondria and Neuroplasticity

(2010) Aiwu Cheng et al.   ASN Neuro

Neurotransmitter signaling in postnatal neurogenesis: The first leg

(2010) Jean-Claude Platel et al.   BRAIN RESEARCH REVIEWS

Spontaneous recurrent seizures after status epilepticus induced by soman in Sprague-Dawley rats

(2010) Marcio De Araujo Furtado et al.   EPILEPSIA

Hippocampal Neurogenesis after Traumatic Brain Injury Is Mediated by Vascular Endothelial Growth Factor Receptor-2 and the Raf/MEK/ERK Cascade

(2010) Kwok-Tung Lu et al.   JOURNAL OF NEUROTRAUMA

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

(2010) Katrin Düvel et al.   MOLECULAR CELL

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

(2010) Wei Deng et al.   NATURE REVIEWS NEUROSCIENCE

Peripheral BDNF Produces Antidepressant-Like Effects in Cellular and Behavioral Models

(2010) Heath D Schmidt et al.   NEUROPSYCHOPHARMACOLOGY

Effects of low-level exposure to sarin and cyclosarin during the 1991 Gulf War on brain function and brain structure in US veterans

(2010) Linda L. Chao et al.   NEUROTOXICOLOGY

Neuropsychological and psychiatric functioning in sheep farmers exposed to low levels of organophosphate pesticides

(2010) Sarah Jane Mackenzie Ross et al.   NEUROTOXICOLOGY AND TERATOLOGY

Impaired auditory and contextual fear conditioning in soman-exposed rats

(2010) Mark C. Moffett et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Intraamygdaloid microinjection of acylated-ghrelin influences passive avoidance learning

(2009) Krisztián Tóth et al.   BEHAVIOURAL BRAIN RESEARCH

Neuropsychological functioning of U.S. Gulf War veterans 10 years after the war

(2009) ROSEMARY TOOMEY et al.   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

Subchronic Alpha-Linolenic Acid Treatment Enhances Brain Plasticity and Exerts an Antidepressant Effect: A Versatile Potential Therapy for Stroke

(2009) Nicolas Blondeau et al.   NEUROPSYCHOPHARMACOLOGY

Intrahippocampal cholinesterase inhibition induces epileptogenesis in mice without evidence of neurodegenerative events

(2009) F. Pernot et al.   NEUROSCIENCE

Primary brain targets of nerve agents: The role of the amygdala in comparison to the hippocampus

(2009) Vassiliki Aroniadou-Anderjaska et al.   NEUROTOXICOLOGY

Dietary supplementation of alpha-linolenic acid in an enriched rapeseed oil diet protects from stroke

(2009) C. Nguemeni et al.   PHARMACOLOGICAL RESEARCH

Effects of nicotine on depressive-like behavior and hippocampal volume of female WKY rats

(2009) Yousef Tizabi et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation

(2009) C. D. Clelland et al.   SCIENCE

mTOR signaling: At the crossroads of plasticity, memory and disease

(2009) Charles A. Hoeffer et al.   TRENDS IN NEUROSCIENCES

Molecular genetic analysis of FGFR1 signalling reveals distinct roles of MAPK and PLCγ1 activation for self-renewal of adult neural stem cells

(2009) Dengke K Ma et al.   Molecular Brain

Long-term consequences of soman poisoning in mice

(2008) Jean-Marc Collombet et al.   BEHAVIOURAL BRAIN RESEARCH

Long-term consequences of soman poisoning in mice

(2008) Stéphanie Coubard et al.   BEHAVIOURAL BRAIN RESEARCH

Electroconvulsive seizure restores neurogenesis and hippocampus-dependent fear memory after disruption by irradiation

(2008) Jennifer L. Warner-Schmidt et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

PPARα ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-κB and AP-1 pathways

(2008) Sriram Ramanan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Proliferating Progenitor Cells: A Required Cellular Element for Induction of Ischemic Tolerance in the Brain

(2008) Samaneh Maysami et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain

(2008) Itaru Imayoshi et al.   NATURE NEUROSCIENCE

TrkB Regulates Hippocampal Neurogenesis and Governs Sensitivity to Antidepressive Treatment

(2008) Yun Li et al.   NEURON

Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice

(2008) T. Deltheil et al.   NEUROPHARMACOLOGY

Soman induces ictogenesis in the amygdala and interictal activity in the hippocampus that are blocked by a GluR5 kainate receptor antagonist in vitro

(2008) J.P. Apland et al.   NEUROSCIENCE

Novel effects of Nelumbo nucifera rhizome extract on memory and neurogenesis in the dentate gyrus of the rat hippocampus

(2008) Woong Mo Yang et al.   NEUROSCIENCE LETTERS

Long-term cognitive deficits accompanied by reduced neurogenesis after soman poisoning

(2008) Marloes J.A. Joosen et al.   NEUROTOXICOLOGY

PUFA induce antidepressant-like effects in parallel to structural and molecular changes in the hippocampus

(2008) Venugopal Reddy Venna et al.   PSYCHONEUROENDOCRINOLOGY

Selective Loss of Brain-Derived Neurotrophic Factor in the Dentate Gyrus Attenuates Antidepressant Efficacy

(2007) Megumi Adachi et al.   BIOLOGICAL PSYCHIATRY