Cell-penetrating peptides: A tool for effective delivery in gene-targeted therapies

CPPpred: prediction of cell penetrating peptides

(2013) Thérèse A. Holton et al.   BIOINFORMATICS

Nucleic acid delivery by cell penetrating peptides derived from dengue virus capsid protein: design and mechanism of action

(2013) João M. Freire et al.   FEBS Journal

Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it

(2013) Douglas B. Kell   FEBS Journal

Cell-penetrating peptides: 20 years later, where do we stand?

(2013) Chérine Bechara et al.   FEBS LETTERS

In silico approaches for designing highly effective cell penetrating peptides

(2013) Ankur Gautam et al.   Journal of Translational Medicine

siRNA-based nanomedicine

(2013) Jing Zhao et al.   Nanomedicine

CRISPR interference (CRISPRi) for sequence-specific control of gene expression

(2013) Matthew H Larson et al.   Nature Protocols

Delivery Systems and Local Administration Routes for Therapeutic siRNA

(2013) Fabiana Testa Moura de Carvalho Vicentini et al.   PHARMACEUTICAL RESEARCH

Intracellular Nucleic Acid Delivery by the Supercharged Dengue Virus Capsid Protein

(2013) João Miguel Freire et al.   PLoS One

New Tool for Genome Surgery

(2013) J. v. d. Oost   SCIENCE

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Novel vaccine strategies against emerging viruses

(2013) Adolfo García-Sastre et al.   Current Opinion in Virology

Peptide Vectors for the Nonviral Delivery of Nucleic Acids

(2012) Jan Hoyer et al.   ACCOUNTS OF CHEMICAL RESEARCH

Nucleic Acid Delivery: The Missing Pieces of the Puzzle?

(2012) Juliane Nguyen et al.   ACCOUNTS OF CHEMICAL RESEARCH

Anticancer Peptide SVS-1: Efficacy Precedes Membrane Neutralization

(2012) Diana Gaspar et al.   BIOCHEMISTRY

The Future of Peptide-based Drugs

(2012) David J. Craik et al.   Chemical Biology & Drug Design

Cell-penetrating peptides: classes, origin, and current landscape

(2012) Francesca Milletti   DRUG DISCOVERY TODAY

Cell-penetrating peptides for the delivery of nucleic acids

(2012) Taavi Lehto et al.   Expert Opinion on Drug Delivery

Cell entry of cell penetrating peptides: tales of tails wagging dogs

(2012) Arwyn T. Jones et al.   JOURNAL OF CONTROLLED RELEASE

Cell-penetrating peptides (CPPs) as a vector for the delivery of siRNAs into cells

(2012) Ikuhiko Nakase et al.   Molecular BioSystems

Cell-penetrating Peptides as Versatile Vehicles for Oligonucleotide Delivery

(2012) Helerin Margus et al.   MOLECULAR THERAPY

Cell-penetrating peptides released from thermosensitive nanoparticles suppress pro-inflammatory cytokine response by specifically targeting inflamed cartilage explants

(2012) Rush L. Bartlett et al.   Nanomedicine-Nanotechnology Biology and Medicine

Cell-penetrating H4 tail peptides potentiate p53-mediated transactivation via inhibition of G9a and HDAC1

(2012) K Heo et al.   ONCOGENE

Cell-penetrating peptides: breaking through to the other side

(2012) Erez Koren et al.   TRENDS IN MOLECULAR MEDICINE

Peptides for cell-selective drug delivery

(2012) Nina Svensen et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Efficient Intracellular Delivery of Nucleic Acid Pharmaceuticals Using Cell-Penetrating Peptides

(2011) Ikuhiko Nakase et al.   ACCOUNTS OF CHEMICAL RESEARCH

Advances in Drug Delivery

(2011) Brian P. Timko et al.   Annual Review of Materials Research

Contributions of Glycosaminoglycan Binding and Clustering to the Biological Uptake of the Nonamphipathic Cell-Penetrating Peptide WR9

(2011) André Ziegler et al.   BIOCHEMISTRY

The cell penetrating ability of the proapoptotic peptide, KLAKLAKKLAKLAK fused to the N-terminal protein transduction domain of translationally controlled tumor protein, MIIYRDLISH

(2011) Hyo Young Kim et al.   BIOMATERIALS

Antimicrobial peptides with cell-penetrating peptide properties and vice versa

(2011) Katrin Splith et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Multifunctional PEGylated 2C5-immunoliposomes containing pH-sensitive bonds and TAT peptide for enhanced tumor cell internalization and cytotoxicity

(2011) Erez Koren et al.   JOURNAL OF CONTROLLED RELEASE

A Cell-penetrating Peptide Suppresses Inflammation by Inhibiting NF-κB Signaling

(2011) Yu Fu Wang et al.   MOLECULAR THERAPY

Bio-inspired, bioengineered and biomimetic drug delivery carriers

(2011) Jin-Wook Yoo et al.   NATURE REVIEWS DRUG DISCOVERY

The design and delivery of a thermally responsive peptide to inhibit S100B-mediated neurodegeneration

(2011) S.M. Hearst et al.   NEUROSCIENCE

Translocation of HIV TAT peptide and analogues induced by multiplexed membrane and cytoskeletal interactions

(2011) A. Mishra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prediction of Cell Penetrating Peptides by Support Vector Machines

(2011) William S. Sanders et al.   PLoS Computational Biology

Potent Delivery of Functional Proteins into Mammalian Cellsin Vitroandin VivoUsing a Supercharged Protein

(2010) James J. Cronican et al.   ACS Chemical Biology

Effect of Mipomersen, an Apolipoprotein B Synthesis Inhibitor, on Low-Density Lipoprotein Cholesterol in Patients With Familial Hypercholesterolemia

(2010) Fatima Akdim et al.   AMERICAN JOURNAL OF CARDIOLOGY

ATTEMPTS System: A Macromolecular Prodrug Strategy for Cancer Drug Delivery

(2010) Yongzhuo Huang et al.   CURRENT PHARMACEUTICAL DESIGN

Cell-penetrating chitosan/doxorubicin/TAT conjugates for efficient cancer therapy

(2010) Jue-Yeon Lee et al.   INTERNATIONAL JOURNAL OF CANCER

Escherichia coliCell Surface Perturbation and Disruption Induced by Antimicrobial Peptides BP100 and pepR

(2010) Carla S. Alves et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ebola haemorrhagic fever

(2010) Heinz Feldmann et al.   LANCET

Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms

(2010) Akin Akinc et al.   MOLECULAR THERAPY

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

HIV-1 Fusion Inhibitor Peptides Enfuvirtide and T-1249 Interact with Erythrocyte and Lymphocyte Membranes

(2010) Pedro M. Matos et al.   PLoS One

Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases

(2010) E. S. Olson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival

(2010) Q. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effective Gene Silencing by Multilayered siRNA-Coated Gold Nanoparticles

(2010) Seung Koo Lee et al.   Small

In vivo biodistribution and efficacy of peptide mediated delivery

(2010) Peter Järver et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Recent advances in the use of cell-penetrating peptides for medical and biological applications☆

(2009) Sonali B. Fonseca et al.   ADVANCED DRUG DELIVERY REVIEWS

Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics

(2009) Frederic Heitz et al.   BRITISH JOURNAL OF PHARMACOLOGY

Five siRNAs Targeting Three SNPs May Provide Therapy for Three-Quarters of Huntington's Disease Patients

(2009) Edith L. Pfister et al.   CURRENT BIOLOGY

Small interfering RNA (siRNA) delivery into murine bone marrow-derived macrophages by electroporation

(2009) Melanie Wiese et al.   JOURNAL OF IMMUNOLOGICAL METHODS

In vivo siRNA delivery with dendritic poly(l-lysine) for the treatment of hypercholesterolemia

(2009) Kazuto Watanabe et al.   Molecular BioSystems

Antimicrobial peptides: linking partition, activity and high membrane-bound concentrations

(2009) Manuel N. Melo et al.   NATURE REVIEWS MICROBIOLOGY

Stimulated endocytosis in penetratin uptake: Effect of arginine and lysine

(2008) Helene L. Åmand et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cell-penetrating peptides: from molecular mechanisms to therapeutics

(2008) May C. Morris et al.   BIOLOGY OF THE CELL

Updates on p53: modulation of p53 degradation as a therapeutic approach

(2008) A Dey et al.   BRITISH JOURNAL OF CANCER

Ultrasound with microbubbles enhances gene expression of plasmid DNA in the liver via intraportal delivery

(2008) Z P Shen et al.   GENE THERAPY

Cell Entry of Arginine-rich Peptides Is Independent of Endocytosis

(2008) Gohar Ter-Avetisyan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhalable siRNA: Potential as a Therapeutic Agent in the Lungs

(2008) Niamh Durcan et al.   MOLECULAR PHARMACEUTICS

Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

(2008) Frank Alexis et al.   MOLECULAR PHARMACEUTICS

Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of α-Tocopherol

(2008) Kazutaka Nishina et al.   MOLECULAR THERAPY

In vivo reprogramming of adult pancreatic exocrine cells to β-cells

(2008) Qiao Zhou et al.   NATURE

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

(2008) Akin Akinc et al.   NATURE BIOTECHNOLOGY

Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters

(2008) E. A. Dubikovskaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protease-Triggered Unveiling of Bioactive Nanoparticles

(2008) Todd J. Harris et al.   Small

Binding and Clustering of Glycosaminoglycans: A Common Property of Mono- and Multivalent Cell-Penetrating Compounds

(2007) André Ziegler et al.   BIOPHYSICAL JOURNAL

Live-cell analysis of cell penetration ability and toxicity of oligo-arginines

(2007) Gisela Tünnemann et al.   JOURNAL OF PEPTIDE SCIENCE