Artemisinin and Curcumin inhibitDrosophilabrain tumor, prolong life span, and restore locomotor activity

Artemisinin induces A549 cell apoptosis dominantly via a reactive oxygen species-mediated amplification activation loop among caspase-9, -8 and -3

(2013) Weijie Gao et al.   APOPTOSIS

Curcumin Inhibits Proliferation and Induces Apoptosis of Human Colorectal Cancer Cells by Activating the Mitochondria Apoptotic Pathway

(2012) Li-da Guo et al.   PHYTOTHERAPY RESEARCH

Curcumin Promotes A-beta Fibrillation and Reduces Neurotoxicity in Transgenic Drosophila

(2012) Ina Caesar et al.   PLoS One

Drosophila melanogaster as a model system for human brain cancers

(2011) Renee D. Read   GLIA

Antitumor Activity of Artemisinin and Its Derivatives: From a Well-Known Antimalarial Agent to a Potential Anticancer Drug

(2011) Maria P. Crespo-Ortiz et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Curcumin-mediated lifespan extension in Caenorhabditis elegans

(2011) Vivian Hsiu-Chuan Liao et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Curcumin induces DNA damage and caffeine-insensitive cell cycle arrest in colorectal carcinoma HCT116 cells

(2011) Jin-Jian Lu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Curcumin inhibits metastatic progression of breast cancer cell through suppression of urokinase-type plasminogen activator by NF-kappa B signaling pathways

(2011) Hong Zong et al.   MOLECULAR BIOLOGY REPORTS

Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma

(2011) Reason Wilken et al.   Molecular Cancer

A Preclinical and Clinical Study of Lithium in Low-Grade Neuroendocrine Tumors

(2011) S. J. Lubner et al.   ONCOLOGIST

Human Disease Models in Drosophila melanogaster and the Role of the Fly in Therapeutic Drug Discovery

(2011) U. B. Pandey et al.   PHARMACOLOGICAL REVIEWS

A Transient Expression of Prospero Promotes Cell Cycle Exit of Drosophila Postembryonic Neurons through the Regulation of Dacapo

(2011) Jordi Colonques et al.   PLoS One

OASIS: Online Application for the Survival Analysis of Lifespan Assays Performed in Aging Research

(2011) Jae-Seong Yang et al.   PLoS One

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

(2010) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Inhibition of NFκB and Pancreatic Cancer Cell and Tumor Growth by Curcumin Is Dependent on Specificity Protein Down-regulation

(2010) Indira Jutooru et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular and Therapeutic Potential and Toxicity of Valproic Acid

(2010) Sébastien Chateauvieux et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Curcumin Extends Life Span, Improves Health Span, and Modulates the Expression of Age-Associated Aging Genes in Drosophila melanogaster

(2010) Kyu-Sun Lee et al.   REJUVENATION RESEARCH

Curcumin blocks brain tumor formation

(2009) Sudarshana Purkayastha et al.   BRAIN RESEARCH

Artemisinin and its derivatives: a novel class of anti-malarial and anti-cancer agents

(2009) Devdutt Chaturvedi et al.   CHEMICAL SOCIETY REVIEWS

Novel Classes of Dimer Antitumour Drug Candidates

(2009) Larry Chow et al.   CURRENT PHARMACEUTICAL DESIGN

Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation

(2009) Edward Owusu-Ansah et al.   NATURE

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Cloning and characterization of the promoter of Hugl-2, the human homologue of Drosophila lethal giant larvae (lgl) polarity gene

(2008) Tim Zimmermann et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Rapid reactive oxygen species (ROS) generation induced by curcumin leads to caspase-dependent and -independent apoptosis in L929 cells

(2008) Faisal Thayyullathil et al.   FREE RADICAL BIOLOGY AND MEDICINE

Drosophilaneuroblast asymmetric divisions: cell cycle regulators, asymmetric protein localization, and tumorigenesis: Figure 1.

(2008) William Chia et al.   JOURNAL OF CELL BIOLOGY