The regulation and function of micrornas in kidney diseases

Tumor suppressive microRNA-1285 regulates novel molecular targets: Aberrant expression and functional significance in renal cell carcinoma

(2015) Hideo Hidaka et al.   Oncotarget

Genome-Wide Epigenetic Regulation of miRNAs in Cancer

(2013) C. Baer et al.   CANCER RESEARCH

miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes

(2013) X. Zhong et al.   DIABETOLOGIA

Micro-RNA Expression in the Urinary Sediment of Patients with Chronic Kidney Diseases

(2013) Cheuk-Chun Szeto et al.   DISEASE MARKERS

Pleiotropic Action of Renal Cell Carcinoma-Dysregulated miRNAs on Hypoxia-Related Signaling Pathways

(2012) Zsuzsanna Lichner et al.   AMERICAN JOURNAL OF PATHOLOGY

MicroRNA 15a, Inversely Correlated to PKCα, Is a Potential Marker to Differentiate between Benign and Malignant Renal Tumors in Biopsy and Urine Samples

(2012) Melanie von Brandenstein et al.   AMERICAN JOURNAL OF PATHOLOGY

Identification of miR-508-3p and miR-509-3p that are associated with cell invasion and migration and involved in the apoptosis of renal cell carcinoma

(2012) Qingna Zhai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The enhancer of zeste homolog 2 (EZH2), a potential therapeutic target, is regulated by miR-101 in renal cancer cells

(2012) Toshihiko Sakurai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

VHL-Regulated MiR-204 Suppresses Tumor Growth through Inhibition of LC3B-Mediated Autophagy in Renal Clear Cell Carcinoma

(2012) Olga Mikhaylova et al.   CANCER CELL

miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms

(2012) U. Senanayake et al.   CARCINOGENESIS

PKHD1 post-transcriptionally modulated by miR-365-1 inhibits cell-cell adhesion

(2012) Jingjing Duan et al.   CELL BIOCHEMISTRY AND FUNCTION

Claudin-14 regulates renal Ca++transport in response to CaSR signalling via a novel microRNA pathway

(2012) Yongfeng Gong et al.   EMBO JOURNAL

Identification of MicroRNAs associated with early relapse after nephrectomy in renal cell carcinoma patients

(2012) Ondrej Slaby et al.   GENES CHROMOSOMES & CANCER

The Clinical Utility of miR-21 as a Diagnostic and Prognostic Marker for Renal Cell Carcinoma

(2012) Hala Faragalla et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

MicroRNAs Regulate Renal Tubule Maturation through Modulation of Pkd1

(2012) V. Patel et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

MicroRNA-324-3p Promotes Renal Fibrosis and Is a Target of ACE Inhibition

(2012) D. Macconi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Upregulation of miR-142-3p in Peripheral Blood Mononuclear Cells of Operationally Tolerant Patients with a Renal Transplant

(2012) R. Danger et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

MicroRNA-494 Reduces ATF3 Expression and Promotes AKI

(2012) Y.-F. Lan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inhibiting MicroRNA-192 Ameliorates Renal Fibrosis in Diabetic Nephropathy

(2012) S. Putta et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Circulating miR-378 and miR-451 in serum are potential biomarkers for renal cell carcinoma

(2012) Martina Redova et al.   Journal of Translational Medicine

Delayed ischemic preconditioning contributes to renal protection by upregulation of miR-21

(2012) Xialian Xu et al.   KIDNEY INTERNATIONAL

Microvesicles derived from endothelial progenitor cells protect the kidney from ischemia–reperfusion injury by microRNA-dependent reprogramming of resident renal cells

(2012) Vincenzo Cantaluppi et al.   KIDNEY INTERNATIONAL

Smad7 suppresses renal fibrosis via altering expression of TGF-β/Smad3-regulated microRNAs

(2012) Arthur C.K. Chung et al.   MOLECULAR THERAPY

Glomerular and tubulointerstitial miR-638, miR-198 and miR-146a expression in lupus nephritis

(2012) JIANXIN LU et al.   NEPHROLOGY

MicroRNAs contribute to the maintenance of cell-type-specific physiological characteristics: miR-192 targets Na+/K+-ATPase β1

(2012) Domagoj Mladinov et al.   NUCLEIC ACIDS RESEARCH

Up-Regulation of MicroRNA-21 Correlates with Lower Kidney Cancer Survival

(2012) Mohd Saif Zaman et al.   PLoS One

microRNA-21 Governs TORC1 Activation in Renal Cancer Cell Proliferation and Invasion

(2012) Nirmalya Dey et al.   PLoS One

Identification of a 4-microRNA Signature for Clear Cell Renal Cell Carcinoma Metastasis and Prognosis

(2012) Xiwei Wu et al.   PLoS One

Genome-Wide MicroRNA Expression Analysis of Clear Cell Renal Cell Carcinoma by Next Generation Deep Sequencing

(2012) Susanne Osanto et al.   PLoS One

Downregulation of miR-205 Modulates Cell Susceptibility to Oxidative and Endoplasmic Reticulum Stresses in Renal Tubular Cells

(2012) Shiyo Muratsu-Ikeda et al.   PLoS One

MicroRNA-34a Modulates MDM4 Expression via a Target Site in the Open Reading Frame

(2012) Pooja Mandke et al.   PLoS One

miR-127 Protects Proximal Tubule Cells against Ischemia/Reperfusion: Identification of Kinesin Family Member 3B as miR-127 Target

(2012) Elia Aguado-Fraile et al.   PLoS One

Urinary MicroRNA-10a and MicroRNA-30d Serve as Novel, Sensitive and Specific Biomarkers for Kidney Injury

(2012) Nan Wang et al.   PLoS One

Reduced Circulating miR-15b Is Correlated with Phosphate Metabolism in Patients with End-Stage Renal Disease on Maintenance Hemodialysis

(2012) Honglei Wang et al.   RENAL FAILURE

MicroRNA-21 Promotes Fibrosis of the Kidney by Silencing Metabolic Pathways

(2012) B. N. Chau et al.   Science Translational Medicine

MicroRNA Circuits in Transforming Growth Factor-β Actions and Diabetic Nephropathy

(2012) Mitsuo Kato et al.   SEMINARS IN NEPHROLOGY

Circulating microRNAs as Biomarkers, Therapeutic Targets, and Signaling Molecules

(2012) Seena K. Ajit   SENSORS

Expression, Circulation, and Excretion Profile of MicroRNA-21, -155, and -18a Following Acute Kidney Injury

(2012) Janani Saikumar et al.   TOXICOLOGICAL SCIENCES

MicroRNA Sequence Profiles of Human Kidney Allografts With or Without Tubulointerstitial Fibrosis

(2012) Iddo Z. Ben-Dov et al.   TRANSPLANTATION

MiR-210 expression in tumor tissue and in vitro effects of its silencing in renal cell carcinoma

(2012) Martina Redova et al.   TUMOR BIOLOGY

Bicc1 links the regulation of cAMP signaling in polycystic kidneys to microRNA-induced gene silencing

(2012) Nathalie Piazzon et al.   Journal of Molecular Cell Biology

Regulatory Effects of microRNA-92 (miR-92) on VHL Gene Expression and the Hypoxic Activation of miR-210 in Clear Cell Renal Cell Carcinoma

(2012) Vladimir A. Valera et al.   Journal of Cancer

DNA Methylation of Tumor Suppressive miRNAs in Non-Hodgkin’s Lymphomas

(2012) Rita Lok-Hay Yim et al.   Frontiers in Genetics

Urinary miR-210 as a Mediator of Acute T-Cell Mediated Rejection in Renal Allograft Recipients

(2011) J. M. Lorenzen et al.   AMERICAN JOURNAL OF TRANSPLANTATION

MicroRNA Profiles in Allograft Tissues and Paired Urines Associate With Chronic Allograft Dysfunction With IF/TA

(2011) M. J. Scian et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Analytical aspects of microRNA in diagnostics: A review

(2011) Mariàngels de Planell-Saguer et al.   ANALYTICA CHIMICA ACTA

Hsa-let-7a functions as a tumor suppressor in renal cell carcinoma cell lines by targeting c-myc

(2011) Yongchao Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autosomal dominant polycystic kidney disease: Genetics, mutations and microRNAs

(2011) Ying-Cai Tan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease

(2011) Priyanka Pandey et al.   BMC Systems Biology

miRNA profiling in metastatic renal cell carcinoma reveals a tumour-suppressor effect for miR-215

(2011) N M A White et al.   BRITISH JOURNAL OF CANCER

MicroRNA-708 Induces Apoptosis and Suppresses Tumorigenicity in Renal Cancer Cells

(2011) S. Saini et al.   CANCER RESEARCH

MicroRNA-1826 directly targets beta-catenin (CTNNB1) and MEK1 (MAP2K1) in VHL-inactivated renal cancer

(2011) Hiroshi Hirata et al.   CARCINOGENESIS

MicroRNA-34a suppresses malignant transformation by targeting c-Myc transcriptional complexes in human renal cell carcinoma

(2011) Soichiro Yamamura et al.   CARCINOGENESIS

Circulating miR-210 Predicts Survival in Critically Ill Patients with Acute Kidney Injury

(2011) J. M. Lorenzen et al.   Clinical Journal of the American Society of Nephrology

Molecular Classification of Adult Renal Epithelial Neoplasms Using MicroRNA Expression and Virtual Karyotyping

(2011) Martin P. Powers et al.   DIAGNOSTIC MOLECULAR PATHOLOGY

The functional significance of miR-1 and miR-133a in renal cell carcinoma

(2011) Kazumori Kawakami et al.   EUROPEAN JOURNAL OF CANCER

Accurate Molecular Classification of Kidney Cancer Subtypes Using MicroRNA Signature

(2011) Youssef M. Youssef et al.   EUROPEAN UROLOGY

MiR-143 enhances adipogenic differentiation of 3T3-L1 cells through targeting the coding region of mouse pleiotrophin

(2011) Can Yi et al.   FEBS LETTERS

MicroRNA-29c Is a Signature MicroRNA under High Glucose Conditions That Targets Sprouty Homolog 1, and Itsin VivoKnockdown Prevents Progression of Diabetic Nephropathy

(2011) Jianyin Long et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-21 Orchestrates High Glucose-induced Signals to TOR Complex 1, Resulting in Renal Cell Pathology in Diabetes

(2011) Nirmalya Dey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Low-dose paclitaxel ameliorates fibrosis in the remnant kidney model by down-regulating miR-192

(2011) Lin Sun et al.   JOURNAL OF PATHOLOGY

Overexpression of miR-210, a downstream target of HIF1α, causes centrosome amplification in renal carcinoma cells

(2011) Chisato Nakada et al.   JOURNAL OF PATHOLOGY

The Pro-Apoptotic Protein Bim Is a MicroRNA Target in Kidney Progenitors

(2011) J. Ho et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TGF- /Smad3 Signaling Promotes Renal Fibrosis by Inhibiting miR-29

(2011) W. Qin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

MicroRNA 802 Stimulates ROMK Channels by Suppressing Caveolin-1

(2011) D.-H. Lin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

miR-335 and miR-34a Promote Renal Senescence by Suppressing Mitochondrial Antioxidative Enzymes

(2011) X.-Y. Bai et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Suppression of microRNA-29 Expression by TGF- 1 Promotes Collagen Expression and Renal Fibrosis

(2011) B. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A microRNA circuit mediates transforming growth factor-β1 autoregulation in renal glomerular mesangial cells

(2011) Mitsuo Kato et al.   KIDNEY INTERNATIONAL

The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy

(2011) Olga Zhdanova et al.   KIDNEY INTERNATIONAL

Altered expression of microRNA miR-146a correlates with the development of chronic renal inflammation

(2011) Osamu Ichii et al.   KIDNEY INTERNATIONAL

Alternative miRNA Biogenesis Pathways and the Interpretation of Core miRNA Pathway Mutants

(2011) Jr-Shiuan Yang et al.   MOLECULAR CELL

Extracellular microRNA: A new source of biomarkers

(2011) Alton Etheridge et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Circulating microRNA expression is reduced in chronic kidney disease

(2011) Calida S. Neal et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

MiR-382 targeting of kallikrein 5 contributes to renal inner medullary interstitial fibrosis

(2011) Alison J. Kriegel et al.   PHYSIOLOGICAL GENOMICS

Integrated Profiling of MicroRNAs and mRNAs: MicroRNAs Located on Xq27.3 Associate with Clear Cell Renal Cell Carcinoma

(2011) Liang Zhou et al.   PLoS One

Specific miRNA signatures are associated with metastasis and poor prognosis in clear cell renal cell carcinoma

(2011) Joana Heinzelmann et al.   WORLD JOURNAL OF UROLOGY

Loss of Inducible Nitric Oxide Synthase Expression in the Mouse Renal Cell Carcinoma Cell Line RENCA Is Mediated by MicroRNA miR-146a

(2010) Christina Perske et al.   AMERICAN JOURNAL OF PATHOLOGY

The VHL-dependent regulation of microRNAs in renal cancer

(2010) Calida S Neal et al.   BMC Medicine

Tumour suppressor microRNA-584 directly targets oncogene Rock-1 and decreases invasion ability in human clear cell renal cell carcinoma

(2010) K Ueno et al.   BRITISH JOURNAL OF CANCER

FoxOs Enforce a Progression Checkpoint to Constrain mTORC1-Activated Renal Tumorigenesis

(2010) Boyi Gan et al.   CANCER CELL

The MicroRNA Spectrum in 12 Body Fluids

(2010) J. A. Weber et al.   CLINICAL CHEMISTRY

The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity

(2010) U. Tran et al.   DEVELOPMENT

E-Cadherin Expression Is Regulated by miR-192/215 by a Mechanism That Is Independent of the Profibrotic Effects of Transforming Growth Factor- 

(2010) B. Wang et al.   DIABETES

miR-200a Prevents Renal Fibrogenesis Through Repression of TGF- 2 Expression

(2010) B. Wang et al.   DIABETES

High glucose down-regulates miR-29a to increase collagen IV production in HK-2 cells

(2010) Bin Du et al.   FEBS LETTERS

Renal Medullary MicroRNAs in Dahl Salt-Sensitive Rats

(2010) Yong Liu et al.   HYPERTENSION

TGF-β-induced MiR-491-5p Expression Promotes Par-3 Degradation in Rat Proximal Tubular Epithelial Cells

(2010) Qin Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of MicroRNA-93 as a Novel Regulator of Vascular Endothelial Growth Factor in Hyperglycemic Conditions

(2010) Jianyin Long et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Post-transcriptional Up-regulation of Tsc-22 by Ybx1, a Target of miR-216a, Mediates TGF-β-induced Collagen Expression in Kidney Cells

(2010) Mitsuo Kato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of miRNA-106b in conventional renal cell carcinoma is a potential marker for prediction of early metastasis after nephrectomy

(2010) Ondrej Slaby et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Accurate Molecular Classification of Renal Tumors Using MicroRNA Expression

(2010) Eddie Fridman et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Regulation of WNK1 Expression by miR-192 and Aldosterone

(2010) E. Elvira-Matelot et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Loss of MicroRNA-192 Promotes Fibrogenesis in Diabetic Nephropathy

(2010) A. Krupa et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Targeted Deletion of Dicer from Proximal Tubules Protects against Renal Ischemia-Reperfusion Injury

(2010) Q. Wei et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

miR-192 Mediates TGF- /Smad3-Driven Renal Fibrosis

(2010) A. C. K. Chung et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The MicroRNA-Processing Enzyme Dicer Maintains Juxtaglomerular Cells

(2010) M. L. S. Sequeira-Lopez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney

(2010) Vidya K. Nagalakshmi et al.   KIDNEY INTERNATIONAL

Posttranscriptional Regulation of MicroRNA Biogenesis in Animals

(2010) Haruhiko Siomi et al.   MOLECULAR CELL

Many ways to generate microRNA-like small RNAs: non-canonical pathways for microRNA production

(2010) Keita Miyoshi et al.   MOLECULAR GENETICS AND GENOMICS

Unknown

(2010) Kirti Bhatt et al.   MOLECULAR MEDICINE

Tonicity-responsive microRNAs contribute to the maximal induction of osmoregulatory transcription factor OREBP in response to high-NaCl hypertonicity

(2010) Weifeng Huang et al.   NUCLEIC ACIDS RESEARCH

MicroRNA-target pairs in human renal epithelial cells treated with transforming growth factor β1: a novel role of miR-382

(2010) Alison J. Kriegel et al.   NUCLEIC ACIDS RESEARCH

Hsa-miR-9 methylation status is associated with cancer development and metastatic recurrence in patients with clear cell renal cell carcinoma

(2010) M A T Hildebrandt et al.   ONCOGENE

miR-23b* targets proline oxidase, a novel tumor suppressor protein in renal cancer

(2010) W Liu et al.   ONCOGENE

Identification of a microRNA signature of renal ischemia reperfusion injury

(2010) J. G. Godwin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrarenal Expression of miRNAs in Patients With Hypertensive Nephrosclerosis

(2009) G. Wang et al.   AMERICAN JOURNAL OF HYPERTENSION

Loss of Heterozygosity at 2q37 in Sporadic Wilms' Tumor: Putative Role for miR-562

(2009) K. M. Drake et al.   CLINICAL CANCER RESEARCH

The miR-30 miRNA family regulates Xenopus pronephros development and targets the transcription factor Xlim1/Lhx1

(2009) R. Agrawal et al.   DEVELOPMENT

Microarray analysis of microRNA expression in renal clear cell carcinoma

(2009) Y. Huang et al.   EJSO

MicroRNA profiling of human kidney cancer subtypes

(2009) Petillo   INTERNATIONAL JOURNAL OF ONCOLOGY

Differential expression of miRNA patterns in renal cell carcinoma and nontumorous tissues

(2009) Zhengjun Yi et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

The miR-17-92 Cluster is Over Expressed in and Has an Oncogenic Effect on Renal Cell Carcinoma

(2009) Tsz-fung F. Chow et al.   JOURNAL OF UROLOGY

Intrarenal expression of microRNAs in patients with IgA nephropathy

(2009) Gang Wang et al.   LABORATORY INVESTIGATION

Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract

(2009) Laura M. Pastorelli et al.   MAMMALIAN GENOME

MicroRNA-17 post-transcriptionally regulates polycystic kidney disease-2 gene and promotes cell proliferation

(2009) Huan Sun et al.   MOLECULAR BIOLOGY REPORTS

CRD-BP Protects the Coding Region of βTrCP1 mRNA from miR-183-Mediated Degradation

(2009) Irina Elcheva et al.   MOLECULAR CELL

TGF-β activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN

(2009) Mitsuo Kato et al.   NATURE CELL BIOLOGY

MicroRNA expression profiles predictive of human renal allograft status

(2009) D. Anglicheau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a MicroRNA Panel for Clear-cell Kidney Cancer

(2009) David Juan et al.   UROLOGY

Microarray-based approach identifies microRNAs and their target functional patterns in polycystic kidney disease

(2008) Priyanka Pandey et al.   BMC GENOMICS

MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy

(2008) Qiang Wang et al.   FASEB JOURNAL

MicroRNA15a modulates expression of the cell-cycle regulator Cdc25A and affects hepatic cystogenesis in a rat model of polycystic kidney disease

(2008) Seung-Ok Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

Genome-wide microRNA expression profiling in renal cell carcinoma: significant down-regulation of miR-141 and miR-200c

(2008) C Nakada et al.   JOURNAL OF PATHOLOGY

Podocyte-Specific Deletion of Dicer Alters Cytoskeletal Dynamics and Causes Glomerular Disease

(2008) S. J. Harvey et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Podocyte-Specific Loss of Functional MicroRNAs Leads to Rapid Glomerular and Tubular Injury

(2008) J. Ho et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Podocyte-Selective Deletion of Dicer Induces Proteinuria and Glomerulosclerosis

(2008) S. Shi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

MicroRNA-10a Binds the 5′UTR of Ribosomal Protein mRNAs and Enhances Their Translation

(2008) Ulf Andersson Ørom et al.   MOLECULAR CELL

MicroRNA-directed transcriptional gene silencing in mammalian cells

(2008) D. H. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serum-based microRNAs: Are we blinded by potential?

(2008) D. B. Jackson   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive analysis of microRNA expression patterns in renal biopsies of lupus nephritis patients

(2008) Yong Dai et al.   RHEUMATOLOGY INTERNATIONAL

miR-148 targets human DNMT3b protein coding region

(2008) A. M. Duursma et al.   RNA

Microarray analysis of MicroRNA expression in acute rejection after renal transplantation

(2008) Weiguo Sui et al.   TRANSPLANT IMMUNOLOGY