The tubulin code: Molecular components, readout mechanisms, and functions

Effects of α-Tubulin K40 Acetylation and Detyrosination on Kinesin-1 Motility in a Purified System

(2014) Neha Kaul et al.   BIOPHYSICAL JOURNAL

Molecular Basis for Age-Dependent Microtubule Acetylation by Tubulin Acetyltransferase

(2014) Agnieszka Szyk et al.   CELL

Genome-wide Analysis Reveals Novel and Discrete Functions for Tubulin Carboxy-Terminal Tails

(2014) Jayne Aiken et al.   CURRENT BIOLOGY

Insights into the Structure and Function of Ciliary and Flagellar Doublet Microtubules

(2014) Richard Linck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Tubulin K40 acetylation is required for contact inhibition of proliferation and cell–substrate adhesion

(2014) Andrea Aguilar et al.   MOLECULAR BIOLOGY OF THE CELL

Towards elucidating the tubulin code

(2014) Annemarie Wehenkel et al.   NATURE CELL BIOLOGY

Regulation of microtubule motors by tubulin isotypes and post-translational modifications

(2014) Minhajuddin Sirajuddin et al.   NATURE CELL BIOLOGY

The journey of the organelle: teamwork and regulation in intracellular transport

(2013) Kari Barlan et al.   CURRENT OPINION IN CELL BIOLOGY

β-Tubulin mutations that cause severe neuropathies disrupt axonal transport

(2013) Shinsuke Niwa et al.   EMBO JOURNAL

Overexpression, purification, and functional analysis of recombinant human tubulin dimer

(2013) Itsushi Minoura et al.   FEBS LETTERS

Cytosolic Carboxypeptidase 5 Removes α- and γ-Linked Glutamates from Tubulin

(2013) Iryna Berezniuk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disruption ofTtll5/StampGene (Tubulin Tyrosine Ligase-like Protein 5/SRC-1 and TIF2-associated Modulatory Protein Gene) in Male Mice Causes Sperm Malformation and Infertility

(2013) Geun-Shik Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis of tubulin tyrosination by tubulin tyrosine ligase

(2013) Andrea E. Prota et al.   JOURNAL OF CELL BIOLOGY

Tubulin glycylases and glutamylases have distinct functions in stabilization and motility of ependymal cilia

(2013) Montserrat Bosch Grau et al.   JOURNAL OF CELL BIOLOGY

Tubulin Tyrosine Ligase and Stathmin Compete for Tubulin Binding In Vitro

(2013) Agnieszka Szyk et al.   JOURNAL OF MOLECULAR BIOLOGY

Effects of tubulin acetylation and tubulin acetyltransferase binding on microtubule structure

(2013) Stuart C. Howes et al.   MOLECULAR BIOLOGY OF THE CELL

αTAT1 catalyses microtubule acetylation at clathrin-coated pits

(2013) Guillaume Montagnac et al.   NATURE

Transglutaminase and Polyamination of Tubulin: Posttranslational Modification for Stabilizing Axonal Microtubules

(2013) Yuyu Song et al.   NEURON

αTAT1 is the major α-tubulin acetyltransferase in mice

(2013) Nereo Kalebic et al.   Nature Communications

An inherited TUBB2B mutation alters a kinesin-binding site and causes polymicrogyria, CFEOM and axon dysinnervation

(2012) Gustav Y. Cederquist et al.   HUMAN MOLECULAR GENETICS

One-step purification of assembly-competent tubulin from diverse eukaryotic sources

(2012) Per O. Widlund et al.   MOLECULAR BIOLOGY OF THE CELL

Tubulin Acetylation Alone Does Not Affect Kinesin-1 Velocity and Run Length In Vitro

(2012) Wilhelm J. Walter et al.   PLoS One

Luminal Localization of α-tubulin K40 Acetylation by Cryo-EM Analysis of Fab-Labeled Microtubules

(2012) Virupakshi Soppina et al.   PLoS One

Design, Overexpression, and Purification of Polymerization-Blocked Yeast αβ-Tubulin Mutants

(2011) Vinu Johnson et al.   BIOCHEMISTRY

Phenotypic spectrum of the tubulin-related disorders and functional implications of disease-causing mutations

(2011) Max A Tischfield et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Tubulin Tyrosine Ligase-like Genesttll3andttll6Maintain Zebrafish Cilia Structure and Motility

(2011) Narendra Pathak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytosolic Carboxypeptidase 1 Is Involved in Processing α- and β-Tubulin

(2011) Iryna Berezniuk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin

(2011) Agnieszka Szyk et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-electron tomography reveals conserved features of doublet microtubules in flagella

(2011) D. Nicastro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

O-GlcNAcylation of tubulin inhibits its polymerization

(2010) Suena Ji et al.   AMINO ACIDS

A Family of Protein-Deglutamylating Enzymes Associated with Neurodegeneration

(2010) Krzysztof Rogowski et al.   CELL

Human TUBB3 Mutations Perturb Microtubule Dynamics, Kinesin Interactions, and Axon Guidance

(2010) Max A. Tischfield et al.   CELL

Tubulin Glutamylation Regulates Ciliary Motility by Altering Inner Dynein Arm Activity

(2010) Swati Suryavanshi et al.   CURRENT BIOLOGY

Tubulin Polyglutamylation Regulates Axonemal Motility by Modulating Activities of Inner-Arm Dyneins

(2010) Tomohiro Kubo et al.   CURRENT BIOLOGY

Identification of Tubulin Deglutamylase amongCaenorhabditis elegansand Mammalian Cytosolic Carboxypeptidases (CCPs)

(2010) Yoshishige Kimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tubulin polyglutamylation stimulates spastin-mediated microtubule severing

(2010) Benjamin Lacroix et al.   JOURNAL OF CELL BIOLOGY

A novel acetylation of β-tubulin by San modulates microtubule polymerization via down-regulating tubulin incorporation

(2010) Chih-Wen Chu et al.   MOLECULAR BIOLOGY OF THE CELL

MEC-17 is an α-tubulin acetyltransferase

(2010) Jyothi S. Akella et al.   NATURE

Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling

(2010) Guoqiang Xu et al.   NATURE BIOTECHNOLOGY

Mutation of Ser172 in Yeast β Tubulin Induces Defects in Microtubule Dynamics and Cell Division

(2010) Fabrice Caudron et al.   PLoS One

Tubulin polyglutamylation is essential for airway ciliary function through the regulation of beating asymmetry

(2010) K. Ikegami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The major  -tubulin K40 acetyltransferase  TAT1 promotes rapid ciliogenesis and efficient mechanosensation

(2010) T. Shida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tubulin Tyrosine Ligase–Like 1 Deficiency Results in Chronic Rhinosinusitis and Abnormal Development of Spermatid Flagella in Mice

(2010) P. Vogel et al.   VETERINARY PATHOLOGY

Recombinant Mammalian Tubulin Polyglutamylase TTLL7 Performs both Initiation and Elongation of Polyglutamylation on β-Tubulin through a Random Sequential Pathway†

(2009) Masahiro Mukai et al.   BIOCHEMISTRY

Evolutionary Divergence of Enzymatic Mechanisms for Posttranslational Polyglycylation

(2009) Krzysztof Rogowski et al.   CELL

TTLL3 Is a Tubulin Glycine Ligase that Regulates the Assembly of Cilia

(2009) Dorota Wloga et al.   DEVELOPMENTAL CELL

Mal3 Masks Catastrophe Events inSchizosaccharomyces pombeMicrotubules by Inhibiting Shrinkage and Promoting Rescue

(2009) Miho Katsuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ubiquitin conjugation system is involved in the disassembly of cilia and flagella

(2009) Kaiyao Huang et al.   JOURNAL OF CELL BIOLOGY

Motor-dependent microtubule disassembly driven by tubulin tyrosination

(2009) Leticia Peris et al.   JOURNAL OF CELL BIOLOGY

Post-Translational Modifications toToxoplasma gondiiα- and β-Tubulins Include Novel C-Terminal Methylation

(2009) Hui Xiao et al.   JOURNAL OF PROTEOME RESEARCH

Tubulin tyrosination navigates the kinesin-1 motor domain to axons

(2009) Yoshiyuki Konishi et al.   NATURE NEUROSCIENCE

Tubulin Tyrosination Is Required for the Proper Organization and Pathfinding of the Growth Cone

(2009) Séverine Marcos et al.   PLoS One

Synaptic activation modifies microtubules underlying transport of postsynaptic cargo

(2009) C. Maas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Neuropathological phenotype of a distinct form of lissencephaly associated with mutations in TUBA1A

(2008) Catherine Fallet-Bianco et al.   BRAIN

Axoneme β-Tubulin Sequence Determines Attachment of Outer Dynein Arms

(2008) Elizabeth C. Raff et al.   CURRENT BIOLOGY

CLIP-170 tracks growing microtubule ends by dynamically recognizing composite EB1/tubulin-binding sites

(2008) Peter Bieling et al.   JOURNAL OF CELL BIOLOGY

HDAC6: a key regulator of cytoskeleton, cell migration and cell–cell interactions

(2008) Agustín Valenzuela-Fernández et al.   TRENDS IN CELL BIOLOGY