Methylene Blue Improves Brain Mitochondrial ABAD Functions and Decreases Aβ in a Neuroinflammatory Alzheimer’s Disease Mouse Model

Protective Role of Methylene Blue in Alzheimer's Disease via Mitochondria and Cytochrome c Oxidase

(2017) Hani Atamna et al.   JOURNAL OF ALZHEIMERS DISEASE

Amyloid-β and Mitochondria in Aging and Alzheimer's Disease: Implications for Synaptic Damage and Cognitive Decline

(2017) P. Hemachandra Reddy et al.   JOURNAL OF ALZHEIMERS DISEASE

Methylene Blue Modulates β-Secretase, Reverses Cerebral Amyloidosis, and Improves Cognition in Transgenic Mice

(2014) Takashi Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Methylene blue does not reverse existing neurofibrillary tangle pathology in the rTg4510 mouse model of tauopathy

(2014) Tara L. Spires-Jones et al.   NEUROSCIENCE LETTERS

Preparation and Characterization of Methylene blue Nanoparticles for Alzheimer’s Disease and Other Tauopathies

(2014) Umesh Jinwal et al.   Current Drug Delivery

Mechanistic Basis of Phenothiazine-Driven Inhibition of Tau Aggregation

(2013) Elias Akoury et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tau-aggregation inhibitor therapy for Alzheimer's disease

(2013) Claude M. Wischik et al.   BIOCHEMICAL PHARMACOLOGY

Therapeutic and preventive effects of methylene blue on Alzheimer's disease pathology in a transgenic mouse model

(2013) V. Paban et al.   NEUROPHARMACOLOGY

Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo

(2012) Erin E. Congdon et al.   Autophagy

Different Fates of Alzheimer’s Disease Amyloid-β Fibrils Remodeled by Biocompatible Small Molecules

(2012) Jacob A. Irwin et al.   BIOMACROMOLECULES

Mitochondrial Dysfunction—A Pharmacological Target in Alzheimer's Disease

(2012) Gunter P. Eckert et al.   MOLECULAR NEUROBIOLOGY

Alzheimer's Disease, Oestrogen and Mitochondria: an Ambiguous Relationship

(2012) Amandine Grimm et al.   MOLECULAR NEUROBIOLOGY

Amyloid-β Peptide Binds to Cytochrome C Oxidase Subunit 1

(2012) Luis Fernando Hernandez-Zimbron et al.   PLoS One

Neuroprotective Actions of Methylene Blue and Its Derivatives

(2012) Ethan Poteet et al.   PLoS One

Methylene Blue as a Cerebral Metabolic and Hemodynamic Enhancer

(2012) Ai-Ling Lin et al.   PLoS One

Alternative Mitochondrial Electron Transfer as a Novel Strategy for Neuroprotection

(2011) Yi Wen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Amyloid-  (A ) Peptide-Binding Alcohol Dehydrogenase-A  Interaction Reduces A  Accumulation and Improves Mitochondrial Function in a Mouse Model of Alzheimer's Disease

(2011) J. Yao et al.   JOURNAL OF NEUROSCIENCE

Inhibition of the Mitochondrial Enzyme ABAD Restores the Amyloid-β-Mediated Deregulation of Estradiol

(2011) Yun-An Lim et al.   PLoS One

Mitochondrial dysfunction - the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-β toxicity

(2011) Anne Eckert et al.   Alzheimers Research & Therapy

The consequences of mitochondrial amyloid β-peptide in Alzheimer's disease

(2010) Kirsty E. A. Muirhead et al.   BIOCHEMICAL JOURNAL

Methylene Blue Reduces Aβ Levels and Rescues Early Cognitive Deficit by Increasing Proteasome Activity

(2010) David X. Medina et al.   BRAIN PATHOLOGY

Mitochondrial quality control and neurological disease: an emerging connection

(2010) Inês Pimenta de Castro et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Amyloid oligomers: formation and toxicity of Aβ oligomers

(2010) Masafumi Sakono et al.   FEBS Journal

Aromatic Small Molecules Remodel Toxic Soluble Oligomers of Amyloid β through Three Independent Pathways

(2010) Ali Reza A. Ladiwala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden

(2010) John C O'Leary et al.   Molecular Neurodegeneration

Beneficial network effects of methylene blue in an amnestic model

(2010) Penny D. Riha et al.   NEUROIMAGE

Neuroprotective mechanism conferred by 17beta-estradiol on the biochemical basis of Alzheimer's disease

(2010) Z. Amtul et al.   NEUROSCIENCE

Amyloid-beta Leads to Impaired Cellular Respiration, Energy Production and Mitochondrial Electron Chain Complex Activities in Human Neuroblastoma Cells

(2009) V. Rhein et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Amino acids variations in Amyloid-β peptides, mitochondrial dysfunction, and new therapies for Alzheimer’s disease

(2009) Hani Atamna   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

(2009) Summer L. Bernstein et al.   Nature Chemistry

Progesterone and Estrogen Regulate Oxidative Metabolism in Brain Mitochondria

(2008) Ronald W. Irwin et al.   ENDOCRINOLOGY

Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation

(2008) Jae Lee et al.   Journal of Neuroinflammation

Mitochondrial Ca2+ Overload Underlies Aβ Oligomers Neurotoxicity Providing an Unexpected Mechanism of Neuroprotection by NSAIDs

(2008) Sara Sanz-Blasco et al.   PLoS One

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

(2008) P. Hemachandra Reddy et al.   TRENDS IN MOLECULAR MEDICINE

Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways

(2007) Hani Atamna et al.   FASEB JOURNAL