N-Methyl, N-propynyl-2-phenylethylamine (MPPE), a Selegiline Analog, Attenuates MPTP-induced Dopaminergic Toxicity with Guaranteed Behavioral Safety: Involvement of Inhibitions of Mitochondrial Oxidative Burdens and p53 Gene-elicited Pro-apoptotic Change
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Title
N-Methyl, N-propynyl-2-phenylethylamine (MPPE), a Selegiline Analog, Attenuates MPTP-induced Dopaminergic Toxicity with Guaranteed Behavioral Safety: Involvement of Inhibitions of Mitochondrial Oxidative Burdens and p53 Gene-elicited Pro-apoptotic Change
Authors
Keywords
<em class=EmphasisTypeItalic >N</em>-Methyl,<em class=EmphasisTypeItalic >N</em>-propynyl-2-phenylethylamine, Mitochondria, Selegiline, Oxidative stress, Behavioral safety, p53 gene knockout mice, Pro-apoptosis, Parkinson’s disease
Journal
MOLECULAR NEUROBIOLOGY
Volume 53, Issue 9, Pages 6251-6269
Publisher
Springer Nature
Online
2015-11-13
DOI
10.1007/s12035-015-9527-1
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- (2013) Christopher A. Lieu et al. PLoS One
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- (2013) C. Perier et al. Cold Spring Harbor Perspectives in Medicine
- Monoamine oxidase-B (MAO-B) inhibitors: implications for disease-modification in Parkinson’s disease
- (2013) Kay Teo et al. Translational Neurodegeneration
- The Neuroprotection of Hydrogen Sulfide Against MPTP-Induced Dopaminergic Neuron Degeneration Involves Uncoupling Protein 2 Rather Than ATP-Sensitive Potassium Channels
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