Inhibitory Effect of Memantine on Streptozotocin-Induced Insulin Receptor Dysfunction, Neuroinflammation, Amyloidogenesis, and Neurotrophic Factor Decline in Astrocytes

Novel Hexapeptide Interacts with Tubulin and Microtubules, Inhibits Aβ Fibrillation, and Shows Significant Neuroprotection

(2015) Atanu Biswas et al.   ACS Chemical Neuroscience

Impaired cognition and cerebral glucose regulation are associated with astrocyte activation in the parenchyma of metabolically stressed APPswe/PS1dE9 mice

(2015) Chi-Wen Yeh et al.   NEUROBIOLOGY OF AGING

Aberrant insulin signaling in Alzheimer's disease: current knowledge

(2015) Gaurav Bedse et al.   Frontiers in Neuroscience

Lenti-GDNF Gene Therapy Protects Against Alzheimer's Disease-Like Neuropathology in 3xTg-AD Mice and MC65 Cells

(2014) Susana Revilla et al.   CNS Neuroscience & Therapeutics

Nine-month follow-up of the insulin receptor signalling cascade in the brain of streptozotocin rat model of sporadic Alzheimer’s disease

(2014) J. Osmanovic Barilar et al.   JOURNAL OF NEURAL TRANSMISSION

Deficiency of GDNF Receptor GFR 1 in Alzheimer's Neurons Results in Neuronal Death

(2014) Y. Konishi et al.   JOURNAL OF NEUROSCIENCE

Protection of streptozotocin induced insulin receptor dysfunction, neuroinflammation and amyloidogenesis in astrocytes by insulin

(2014) N. Rajasekar et al.   NEUROPHARMACOLOGY

Ginsenosides attenuate methylglyoxal-induced impairment of insulin signaling and subsequent apoptosis in primary astrocytes

(2014) John M.T. Chu et al.   NEUROPHARMACOLOGY

Neuroprotective effect of curcumin on okadaic acid induced memory impairment in mice

(2013) N. Rajasekar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

LPS induces mediators of neuroinflammation, cell proliferation, and GFAP expression in human astrocytoma cells U373MG: the anti-inflammatory and anti-proliferative effect of guggulipid

(2013) Rituraj Niranjan et al.   NEUROLOGICAL SCIENCES

Okadaic acid-induced Tau phosphorylation in rat brain: Role of NMDA receptor

(2013) P.K. Kamat et al.   NEUROSCIENCE

Cognitive decline in STZ-3V rats is largely due to dysfunctional insulin signalling through the dentate gyrus

(2012) Akiko Sheala Shingo et al.   BEHAVIOURAL BRAIN RESEARCH

Intracerebroventricular administration of an insulin analogue recovers STZ-induced cognitive decline in rats

(2012) Akiko Sheala Shingo et al.   BEHAVIOURAL BRAIN RESEARCH

The effect of guggulipid and nimesulide on MPTP-induced mediators of neuroinflammation in rat astrocytoma cells, C6

(2012) Rituraj Niranjan et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes

(2012) Philip T.T. Ly et al.   JOURNAL OF CLINICAL INVESTIGATION

A study on neuroinflammation and NMDA receptor function in STZ (ICV) induced memory impaired rats

(2012) Shivika Rai et al.   JOURNAL OF NEUROIMMUNOLOGY

Astrocyte Activation: A Key Step in Rotenone Induced Cytotoxicity and DNA Damage

(2012) Supriya Swarnkar et al.   NEUROCHEMICAL RESEARCH

Lithium, phenserine, memantine and pioglitazone reverse memory deficit and restore phospho-GSK3β decreased in hippocampus in intracerebroventricular streptozotocin induced memory deficit model

(2011) Teresa Ponce-Lopez et al.   BRAIN RESEARCH

Guggulipid and Nimesulide Differentially Regulated Inflammatory Genes mRNA Expressions via Inhibition of NF-kB and CHOP Activation in LPS-Stimulated Rat Astrocytoma Cells, C6

(2011) Rituraj Niranjan et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Glucocorticoids Facilitate Astrocytic Amyloid-β Peptide Deposition by Increasing the Expression of APP and BACE1 and Decreasing the Expression of Amyloid-β-Degrading Proteases

(2011) Yanyan Wang et al.   ENDOCRINOLOGY

Insulin receptor signaling in rat hippocampus: A study in STZ (ICV) induced memory deficit model

(2011) Rahul Agrawal et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

The effect of amyloid associated proteins on the expression of genes involved in amyloid-β clearance by adult human astrocytes

(2011) Sandra D. Mulder et al.   EXPERIMENTAL NEUROLOGY

IL-1R-Associated Kinase-1 Mediates Protein Kinase C -Induced IL-1  Production in Monocytes

(2011) R. L. Tiwari et al.   JOURNAL OF IMMUNOLOGY

The contribution of activated astrocytes to Aβ production: Implications for Alzheimer's disease pathogenesis

(2011) Jie Zhao et al.   Journal of Neuroinflammation

Microarray analysis of the astrocyte transcriptome in the aging brain: relationship to Alzheimer's pathology and APOE genotype

(2011) Julie E. Simpson et al.   NEUROBIOLOGY OF AGING

Amitriptyline-Mediated Cognitive Enhancement in Aged 3×Tg Alzheimer's Disease Mice Is Associated with Neurogenesis and Neurotrophic Activity

(2011) Wayne Chadwick et al.   PLoS One

Insulin Promotes Glycogen Storage and Cell Proliferation in Primary Human Astrocytes

(2011) Martin Heni et al.   PLoS One

Integrated Brain Circuits: Astrocytic Networks Modulate Neuronal Activity and Behavior

(2010) Michael M. Halassa et al.   Annual Review of Physiology

Towards Disease-Modifying Treatment of Alzheimers Disease: Drugs Targeting β -Amyloid

(2010) V. Frisardi et al.   Current Alzheimer Research

Insulin deficiency exacerbates cerebral amyloidosis and behavioral deficits in an Alzheimer transgenic mouse model

(2010) Xu Wang et al.   Molecular Neurodegeneration

Long-term potentiation depends on release of d-serine from astrocytes

(2010) Christian Henneberger et al.   NATURE

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Memantine lowers amyloid-β peptide levels in neuronal cultures and in APP/PS1 transgenic mice

(2009) George M. Alley et al.   JOURNAL OF NEUROSCIENCE RESEARCH

A study of brain insulin receptors, AChE activity and oxidative stress in rat model of ICV STZ induced dementia

(2009) Rahul Agrawal et al.   NEUROPHARMACOLOGY

Novel Neuroprotective Mechanisms of Memantine: Increase in Neurotrophic Factor Release from Astroglia and Anti-Inflammation by Preventing Microglial Activation

(2009) Hung-Ming Wu et al.   NEUROPSYCHOPHARMACOLOGY

Effects of memantine on soluble Αβ25-35-induced changes in peptidergic and glial cells in Alzheimer's disease model rat brain regions

(2009) M. Arif et al.   NEUROSCIENCE

Effect of curcumin on brain insulin receptors and memory functions in STZ (ICV) induced dementia model of rat

(2009) Rahul Agrawal et al.   PHARMACOLOGICAL RESEARCH

Tripartite synapses: astrocytes process and control synaptic information

(2009) Gertrudis Perea et al.   TRENDS IN NEUROSCIENCES

Astroglia in dementia and Alzheimer's disease

(2008) J J Rodríguez et al.   CELL DEATH AND DIFFERENTIATION