Preferential Heme Oxygenase-1 Activation in Striatal Astrocytes Antagonizes Dopaminergic Neuron Degeneration in MPTP-Intoxicated Mice

Intrastriatal GDNF gene transfer by inducible lentivirus vectors protects dopaminergic neurons in a rat model of parkinsonism

(2014) Sha-Sha Chen et al.   EXPERIMENTAL NEUROLOGY

Pharmacologically controlled, discontinuous GDNF gene therapy restores motor function in a rat model of Parkinson's disease

(2014) Julia Tereshchenko et al.   NEUROBIOLOGY OF DISEASE

Oxidative Stress-Induced Signaling Pathways Implicated in the Pathogenesis of Parkinson’s Disease

(2014) Georgia S. Gaki et al.   NEUROMOLECULAR MEDICINE

Emerging therapies for Parkinson's disease: From bench to bedside

(2014) F.I. Tarazi et al.   PHARMACOLOGY & THERAPEUTICS

Human Neural Stem Cells Survive Long Term in the Midbrain of Dopamine-Depleted Monkeys After GDNF Overexpression and Project Neurites Toward an Appropriate Target

(2014) Dustin R. Wakeman et al.   Stem Cells Translational Medicine

Heme Oxygenase-1 As a Target for Drug Discovery

(2013) Roberto Motterlini et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondria-targeted antioxidants for treatment of Parkinson's disease: Preclinical and clinical outcomes

(2013) Huajun Jin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Glutathione metabolism and Parkinson's disease

(2013) Michelle Smeyne et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of the Nrf2 antioxidant pathway by microRNAs: New players in micromanaging redox homeostasis

(2013) Xinghua Cheng et al.   FREE RADICAL BIOLOGY AND MEDICINE

The systemic administration of oleoylethanolamide exerts neuroprotection of the nigrostriatal system in experimental Parkinsonism

(2013) Ramiro Gonzalez-Aparicio et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Role of HO-1 in the Arsenite-Induced Neurotoxicity in Primary Cultured Cortical Neurons

(2013) Y. C. Teng et al.   MOLECULAR NEUROBIOLOGY

Targeting 5-HT1A receptors in astrocytes to protect dopaminergic neurons in parkinsonian models

(2013) Ikuko Miyazaki et al.   NEUROBIOLOGY OF DISEASE

Peptide hormone ghrelin enhances neuronal excitability by inhibition of Kv7/KCNQ channels

(2013) Limin Shi et al.   Nature Communications

Antioxidant and bioenergetic coupling between neurons and astrocytes

(2012) Seila Fernandez-Fernandez et al.   BIOCHEMICAL JOURNAL

Astrocytes conspire with neurons during progression of neurological disease

(2012) James C McGann et al.   CURRENT OPINION IN NEUROBIOLOGY

α-Synuclein expression and Nrf2 deficiency cooperate to aggravate protein aggregation, neuronal death and inflammation in early-stage Parkinson's disease

(2012) Isabel Lastres-Becker et al.   HUMAN MOLECULAR GENETICS

Astrocyte-Specific Overexpression of Nrf2 Delays Motor Pathology and Synuclein Aggregation throughout the CNS in the Alpha-Synuclein Mutant (A53T) Mouse Model

(2012) L. Gan et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism

(2012) David N. Hauser et al.   NEUROBIOLOGY OF DISEASE

Pharmacological Targeting of the Transcription Factor Nrf2 at the Basal Ganglia Provides Disease Modifying Therapy for Experimental Parkinsonism

(2011) Agnieszka Jazwa et al.   ANTIOXIDANTS & REDOX SIGNALING

Modulation of Nrf2/ARE Pathway by Food Polyphenols: A Nutritional Neuroprotective Strategy for Cognitive and Neurodegenerative Disorders

(2011) Giovanni Scapagnini et al.   MOLECULAR NEUROBIOLOGY

Glia: Initiators and progressors of pathology in Parkinson's disease

(2011) Glenda M. Halliday et al.   MOVEMENT DISORDERS

Inhaled Hydrogen Sulfide Prevents Neurodegeneration and Movement Disorder in a Mouse Model of Parkinson's Disease

(2010) Kotaro Kida et al.   ANTIOXIDANTS & REDOX SIGNALING

Different Susceptibility to the Parkinson's Toxin MPTP in Mice Lacking the Redox Master Regulator Nrf2 or Its Target Gene Heme Oxygenase-1

(2010) Nadia G. Innamorato et al.   PLoS One

Neuroglia in neurodegeneration

(2009) Michael T. Heneka et al.   BRAIN RESEARCH REVIEWS

The Nrf2–ARE cytoprotective pathway in astrocytes

(2009) Marcelo R. Vargas et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Heme oxygenase-1 and neurodegeneration: expanding frontiers of engagement

(2009) Hyman M. Schipper et al.   JOURNAL OF NEUROCHEMISTRY

HO-1-mediated macroautophagy: a mechanism for unregulated iron deposition in aging and degenerating neural tissues

(2009) Hillel Zukor et al.   JOURNAL OF NEUROCHEMISTRY

The mechanism of heme oxygenase-1 action involved in the enhancement of neurotrophic factor expression

(2009) Shih-Ya Hung et al.   NEUROPHARMACOLOGY

Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

(2009) Pei-Chun Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protective Effects of Neurotrophic Factor–Secreting Cells in a 6-OHDA Rat Model of Parkinson Disease

(2009) Ofer Sadan et al.   STEM CELLS AND DEVELOPMENT

Microglia and astroglia prevent oxidative stress-induced neuronal cell death: Implications for aceruloplasminemia

(2008) Satoru Oshiro et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Heme oxygenase-1–derived carbon monoxide enhances the host defense response to microbial sepsis in mice

(2008) Su Wol Chung et al.   JOURNAL OF CLINICAL INVESTIGATION

Overexpression of Heme Oxygenase-1 Protects Dopaminergic Neurons against 1-Methyl-4-Phenylpyridinium-Induced Neurotoxicity

(2008) S.-Y. Hung et al.   MOLECULAR PHARMACOLOGY

Ginkgo Biloba Extract Neuroprotective Action Is Dependent on Heme Oxygenase 1 in Ischemic Reperfusion Brain Injury

(2008) Sofiyan Saleem et al.   STROKE

Glial reactions in Parkinson's disease

(2007) Patrick L. McGeer et al.   MOVEMENT DISORDERS