Stall no more at polyproline stretches with the translation elongation factors EF-P and IF-5A

Exploration of the Arrest Peptide Sequence Space Reveals Arrest-enhanced Variants

(2015) Florian Cymer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Entropic Contribution of Elongation Factor P to Proline Positioning at the Catalytic Center of the Ribosome

(2015) Lili K. Doerfel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Arginine-rhamnosylation as new strategy to activate translation elongation factor P

(2015) Jürgen Lassak et al.   Nature Chemical Biology

Cyclic Rhamnosylated Elongation Factor P Establishes Antibiotic Resistance in Pseudomonas aeruginosa

(2015) Andrei Rajkovic et al.   mBio

Maintenance of protein synthesis reading frame by EF-P and m1G37-tRNA

(2015) Howard B. Gamper et al.   Nature Communications

High-Precision Analysis of Translational Pausing by Ribosome Profiling in Bacteria Lacking EFP

(2015) Christopher J. Woolstenhulme et al.   Cell Reports

The hypusine-containing translation factor eIF5A

(2014) Thomas E. Dever et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

A novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformation

(2014) H. Sievert et al.   Disease Models & Mechanisms

Elongation Factor P and Modifying Enzyme PoxA Are Necessary for Virulence of Shigella flexneri

(2014) Hannah E. Marman et al.   INFECTION AND IMMUNITY

Translation Initiation Rate Determines the Impact of Ribosome Stalling on Bacterial Protein Synthesis

(2014) Steven J. Hersch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The non-canonical hydroxylase structure of YfcM reveals a metal ion-coordination motif required for EF-P hydroxylation

(2014) Kan Kobayashi et al.   NUCLEIC ACIDS RESEARCH

Translational stalling at polyproline stretches is modulated by the sequence context upstream of the stall site

(2014) Agata L. Starosta et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Analyses and Functional Classification of Proline Repeat-Rich Proteins: Potential Role of eIF5A in Eukaryotic Evolution

(2014) Ajeet Mandal et al.   PLoS One

A Conserved Proline Triplet in Val-tRNA Synthetase and the Origin of Elongation Factor P

(2014) Agata L. Starosta et al.   Cell Reports

The Effects of Codon Context on In Vivo Translation Speed

(2014) Fabienne F. V. Chevance et al.   PLoS Genetics

EF-P Dependent Pauses Integrate Proximal and Distal Signals during Translation

(2014) Sara Elgamal et al.   PLoS Genetics

eIF5A and EF-P: two unique translation factors are now traveling the same road

(2014) Danuza Rossi et al.   Wiley Interdisciplinary Reviews-RNA

Crystallization and preliminary X-ray crystallographic analysis of YfcM: an important factor for EF-P hydroxylation

(2014) Kan Kobayashi et al.   Acta Crystallographica Section F-Structural Biology Communications

Elongation factor P: Function and effects on bacterial fitness

(2013) Lili K. Doerfel et al.   BIOPOLYMERS

(R)-β-Lysine-modified Elongation Factor P Functions in Translation Elongation

(2013) Tammy J. Bullwinkle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

eIF5A Promotes Translation of Polyproline Motifs

(2013) Erik Gutierrez et al.   MOLECULAR CELL

Energy barriers and driving forces in tRNA translocation through the ribosome

(2013) Lars V Bock et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular evolution of protein-RNA mimicry as a mechanism for translational control

(2013) A. Katz et al.   NUCLEIC ACIDS RESEARCH

Proline: The Distribution, Frequency, Positioning, and Common Functional Roles of Proline and Polyproline Sequences in the Human Proteome

(2013) Alexander A. Morgan et al.   PLoS One

A Comprehensive Analysis of the Importance of Translation Initiation Factors for Haloferax volcanii Applying Deletion and Conditional Depletion Mutants

(2013) Katrin Gäbel et al.   PLoS One

Distinct XPPX sequence motifs induce ribosome stalling, which is rescued by the translation elongation factor EF-P

(2013) L. Peil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Getting Past Polyproline Pauses

(2013) A. R. Buskirk et al.   SCIENCE

Divergent Protein Motifs Direct Elongation Factor P-Mediated Translational Regulation in Salmonella enterica and Escherichia coli

(2013) S. J. Hersch et al.   mBio

Aromatic–Proline Interactions: Electronically Tunable CH/π Interactions

(2012) Neal J. Zondlo   ACCOUNTS OF CHEMICAL RESEARCH

Acetylation regulates subcellular localization of eukaryotic translation initiation factor 5A (eIF5A)

(2012) Muhammad Ishfaq et al.   FEBS LETTERS

Lys34 of translation elongation factor EF-P is hydroxylated by YfcM

(2012) Lauri Peil et al.   Nature Chemical Biology

EF-P Is Essential for Rapid Synthesis of Proteins Containing Consecutive Proline Residues

(2012) L. K. Doerfel et al.   SCIENCE

Translation Elongation Factor EF-P Alleviates Ribosome Stalling at Polyproline Stretches

(2012) S. Ude et al.   SCIENCE

β-Lysine discrimination by lysyl-tRNA synthetase

(2011) Marla S. Gilreath et al.   FEBS LETTERS

A Mutation in the poxA Gene of Salmonella enterica Serovar Typhimurium Alters Protein Production, Elevates Susceptibility to Environmental Challenges, and Decreases Swine Colonization

(2011) Shawn M.D. Bearson et al.   Foodborne Pathogens and Disease

Loss of Elongation Factor P Disrupts Bacterial Outer Membrane Integrity

(2011) S. B. Zou et al.   JOURNAL OF BACTERIOLOGY

Post-translational Modification by β-Lysylation Is Required for Activity of Escherichia coli Elongation Factor P (EF-P)

(2011) Jong-Hwan Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Brucella abortus efp gene is required for an efficient internalization in HeLa cells

(2011) Florencia Iannino et al.   MICROBIAL PATHOGENESIS

The tRNA synthetase paralog PoxA modifies elongation factor-P with (R)-β-lysine

(2011) Hervé Roy et al.   Nature Chemical Biology

Nascentome Analysis Uncovers Futile Protein Synthesis in Escherichia coli

(2011) Koreaki Ito et al.   PLoS One

Crystal structure of elongation factor P from Pseudomonas aeruginosa at 1.75 å resolution

(2011) Sarah Choi et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Crystallization and preliminary X-ray crystallographic study of GenX, a lysyl-tRNA synthetase paralogue from Escherichia coli, in complex with translation elongation factor P

(2010) Tomomi Sumida et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Divergent stalling sequences sense and control cellular physiology

(2010) Koreaki Ito et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Predicting the pathway involved in post-translational modification of Elongation factor P in a subset of bacterial species

(2010) Marc Bailly et al.   Biology Direct

Evolution and Multifarious Horizontal Transfer of an Alternative Biosynthetic Pathway for the Alternative Polyaminesym-Homospermidine

(2010) Frances L. Shaw et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PoxA, YjeK, and Elongation Factor P Coordinately Modulate Virulence and Drug Resistance in Salmonella enterica

(2010) William Wiley Navarre et al.   MOLECULAR CELL

A paralog of lysyl-tRNA synthetase aminoacylates a conserved lysine residue in translation elongation factor P

(2010) Tatsuo Yanagisawa et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

pH-sensitivity of the ribosomal peptidyl transfer reaction dependent on the identity of the A-site aminoacyl-tRNA

(2010) M. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Production of active recombinant eIF5A: reconstitution in E.coli of eukaryotic hypusine modification of eIF5A by its coexpression with modifying enzymes

(2010) J. H. Park et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Functional significance of eIF5A and its hypusine modification in eukaryotes

(2009) M. H. Park et al.   AMINO ACIDS

Genetic Identification of Nascent Peptides That Induce Ribosome Stalling

(2009) Douglas R. Tanner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TheDrosophiladeoxyhypusine hydroxylase homologueneroand its target eIF5A are required for cell growth and the regulation of autophagy

(2009) Prajal H. Patel et al.   JOURNAL OF CELL BIOLOGY

Induction Kinetics of a Conditional pH Stress Response System in Escherichia coli

(2009) Georg Fritz et al.   JOURNAL OF MOLECULAR BIOLOGY

The membrane-integrated transcriptional activator CadC ofEscherichia colisenses lysine indirectly via the interaction with the lysine permease LysP

(2009) Larissa Tetsch et al.   MOLECULAR MICROBIOLOGY

Hypusine-containing protein eIF5A promotes translation elongation

(2009) Preeti Saini et al.   NATURE

Spontaneous formation of the unlocked state of the ribosome is a multistep process

(2009) J. B. Munro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of human eIF5A1: Insight into functional similarity of human eIF5A1 and eIF5A2

(2009) Yufeng Tong et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Formation of the First Peptide Bond: The Structure of EF-P Bound to the 70S Ribosome

(2009) G. Blaha et al.   SCIENCE

Peptidyl-prolyl-tRNA at the ribosomal P-site reacts poorly with puromycin

(2008) Hiroki Muto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interactions of elongation factor EF-P with the Escherichia coli ribosome

(2008) Hiroyuki Aoki et al.   FEBS Journal

Modulation of the Rate of Peptidyl Transfer on the Ribosome by the Nature of Substrates

(2008) Ingo Wohlgemuth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Towards environmental systems biology of Shewanella

(2008) James K. Fredrickson et al.   NATURE REVIEWS MICROBIOLOGY

Slow peptide bond formation by proline and other N-alkylamino acids in translation

(2008) M. Y. Pavlov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA