Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters

Engineered Streptomyces avermitilis Host for Heterologous Expression of Biosynthetic Gene Cluster for Secondary Metabolites

(2013) Mamoru Komatsu et al.   ACS Synthetic Biology

Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B0171

(2012) Junji Inokoshi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Genome Mining inStreptomyces. Elucidation of the Role of Baeyer−Villiger Monooxygenases and Non-Heme Iron-Dependent Dehydrogenase/Oxygenases in the Final Steps of the Biosynthesis of Pentalenolactone and Neopentalenolactone

(2011) Myung-Ji Seo et al.   BIOCHEMISTRY

Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes

(2011) Steven T Pullan et al.   BMC GENOMICS

Total synthesis and absolute configuration of avenolide, extracellular factor in Streptomyces avermitilis

(2011) Miho Uchida et al.   JOURNAL OF ANTIBIOTICS

Complete Genome Sequence of Streptomyces cattleya NRRL 8057, a Producer of Antibiotics and Fluorometabolites

(2011) V. Barbe et al.   JOURNAL OF BACTERIOLOGY

Genome Mining inStreptomyces. Discovery of an Unprecedented P450-Catalyzed Oxidative Rearrangement That Is the Final Step in the Biosynthesis of Pentalenolactone

(2011) Dongqing Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Avenolide, a Streptomyces hormone controlling antibiotic production in Streptomyces avermitilis

(2011) S. Kitani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Sequence of a 1.8-Mb Bacterial Linear Plasmid Reveals a Rich Evolutionary Reservoir of Secondary Metabolic Pathways

(2010) Marnix H. Medema et al.   Genome Biology and Evolution

Pentalenic acid is a shunt metabolite in the biosynthesis of the pentalenolactone family of metabolites: hydroxylation of 1-deoxypentalenic acid mediated by CYP105D7 (SAV_7469) of Streptomyces avermitilis

(2010) Satoshi Takamatsu et al.   JOURNAL OF ANTIBIOTICS

Genome Sequence of the Milbemycin-Producing Bacterium Streptomyces bingchenggensis

(2010) X.-J. Wang et al.   JOURNAL OF BACTERIOLOGY

Regio- and Stereospecificity of Filipin Hydroxylation Sites Revealed by Crystal Structures of Cytochrome P450 105P1 and 105D6 fromStreptomyces avermitilis

(2010) Lian-Hua Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome Mining inStreptomyces avermitilis: Cloning and Characterization of SAV_76, the Synthase for a New Sesquiterpene, Avermitilol

(2010) Wayne K. W. Chou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Streptomyces scabies87-22 Contains a Coronafacic Acid-Like Biosynthetic Cluster That Contributes to Plant–Microbe Interactions

(2010) Dawn R. D. Bignell et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism

(2010) M. Komatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of a silent sesquiterpenoid biosynthetic pathway in Streptomyces avermitilis controlling epi-isozizaene albaflavenone biosynthesis and isolation of a new oxidized epi-isozizaene metabolite

(2010) Satoshi Takamatsu et al.   Microbial Biotechnology

Genome Mining inStreptomyces avermitilis: A Biochemical Baeyer−Villiger Reaction and Discovery of a New Branch of the Pentalenolactone Family Tree

(2009) Jiaoyang Jiang et al.   BIOCHEMISTRY

Analysis of Two Additional Signaling Molecules in Streptomyces coelicolor and the Development of a Butyrolactone-Specific Reporter System

(2009) Nai-Hua Hsiao et al.   CHEMISTRY & BIOLOGY

Biosynthesis of the Sesquiterpene Antibiotic Albaflavenone inStreptomyces coelicolor. Mechanism and Stereochemistry of the Enzymatic Formation of Epi-isozizaene

(2009) Xin Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genomic basis for natural product biosynthetic diversity in the actinomycetes

(2009) Markus Nett et al.   NATURAL PRODUCT REPORTS

Engineered production of iso-migrastatin in heterologous Streptomyces hosts

(2008) Zhiyang Feng et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Crystal Structures of Cytochrome P450 105P1 from Streptomyces avermitilis: Conformational Flexibility and Histidine Ligation State

(2008) L.-H. Xu et al.   JOURNAL OF BACTERIOLOGY

Genome Sequence of the Streptomycin-Producing Microorganism Streptomyces griseus IFO 13350

(2008) Y. Ohnishi et al.   JOURNAL OF BACTERIOLOGY

Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol

(2008) M. Komatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA