p53-Regulated Networks of Protein, mRNA, miRNA, and lncRNA Expression Revealed by Integrated Pulsed Stable Isotope Labeling With Amino Acids in Cell Culture (pSILAC) and Next Generation Sequencing (NGS) Analyses

Repression of c-Kit by p53 is mediated by miR-34 and is associated with reduced chemoresistance, migration and stemness

(2015) Helge Siemens et al.   Oncotarget

MIR34Aregulates autophagy and apoptosis by targetingHMGB1in the retinoblastoma cell

(2014) Ke Liu et al.   Autophagy

The emerging role of tumor-suppressive microRNA-218 in targeting glioblastoma stemness

(2014) Xingchun Gao et al.   CANCER LETTERS

lncRNA Directs Cooperative Epigenetic Regulation Downstream of Chemokine Signals

(2014) Zhen Xing et al.   CELL

The transcription factor p53: Not a repressor, solely an activator

(2014) Martin Fischer et al.   CELL CYCLE

miR-92a family and their target genes in tumorigenesis and metastasis

(2014) Molin Li et al.   EXPERIMENTAL CELL RESEARCH

A miR-155-dependent microRNA hierarchy in dendritic cell maturation and macrophage activation

(2014) Anne Dueck et al.   FEBS LETTERS

Identification and analysis of large intergenic non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53-binding sites

(2014) Masashi Idogawa et al.   HUMAN MOLECULAR GENETICS

IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis

(2014) Matjaz Rokavec et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-200c inhibits metastasis of breast cancer cells by targeting HMGB1

(2014) Bao-ping Chang et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

The multilayered complexity of ceRNA crosstalk and competition

(2014) Yvonne Tay et al.   NATURE

ProteomeXchange provides globally coordinated proteomics data submission and dissemination

(2014) Juan A Vizcaíno et al.   NATURE BIOTECHNOLOGY

miR-1207-5p and miR-1266 suppress gastric cancer growth and invasion by targeting telomerase reverse transcriptase

(2014) L Chen et al.   Cell Death & Disease

Genome-wide analysis of the human p53 transcriptional network unveils a lncRNA tumour suppressor signature

(2014) Yolanda Sánchez et al.   Nature Communications

A Comprehensive and High-Resolution Genome-wide Response of p53 to Stress

(2014) Gue Su Chang et al.   Cell Reports

HMGB1 in Cancer: Good, Bad, or Both?

(2013) R. Kang et al.   CLINICAL CANCER RESEARCH

SNAIL and miR-34a feed-forward regulation of ZNF281/ZBP99 promotes epithelial-mesenchymal transition

(2013) Stefanie Hahn et al.   EMBO JOURNAL

The association of taxane resistance genes with the clinical course of ovarian carcinoma

(2013) Marie Ehrlichova et al.   GENOMICS

AP4 is a mediator of epithelial–mesenchymal transition and metastasis in colorectal cancer

(2013) Rene Jackstadt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mitochondrial translation factors ofTrypanosoma brucei:elongation factor-Tu has a unique subdomain that is essential for its function

(2013) Marina Cristodero et al.   MOLECULAR MICROBIOLOGY

Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells

(2013) Daniel Menendez et al.   NUCLEIC ACIDS RESEARCH

Activities at the Universal Protein Resource (UniProt)

(2013)   NUCLEIC ACIDS RESEARCH

Downregulation of miR-486-5p contributes to tumor progression and metastasis by targeting protumorigenic ARHGAP5 in lung cancer

(2013) J Wang et al.   ONCOGENE

TTK/hMPS1 Is an Attractive Therapeutic Target for Triple-Negative Breast Cancer

(2013) Virginie Maire et al.   PLoS One

miR-221/222 Targets Adiponectin Receptor 1 to Promote the Epithelial-to-Mesenchymal Transition in Breast Cancer

(2013) Michael S. Hwang et al.   PLoS One

Characterization of the p53 Cistrome – DNA Binding Cooperativity Dissects p53's Tumor Suppressor Functions

(2013) Katharina Schlereth et al.   PLoS Genetics

p53/HMGB1 Complexes Regulate Autophagy and Apoptosis

(2012) K. M. Livesey et al.   CANCER RESEARCH

Distinct p53 genomic binding patterns in normal and cancer-derived human cells

(2012) Krassimira Botcheva et al.   CELL CYCLE

miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions

(2012) Helge Siemens et al.   CELL CYCLE

Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis

(2012) F Nikulenkov et al.   CELL DEATH AND DIFFERENTIATION

PIM1 kinase as a target for cancer therapy

(2012) Anna Lena Merkel et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Ultrashort and progressive 4sU-tagging reveals key characteristics of RNA processing at nucleotide resolution

(2012) L. Windhager et al.   GENOME RESEARCH

An iTRAQ Proteomics Screen Reveals the Effects of the MDM2 Binding Ligand Nutlin-3 on Cellular Proteostasis

(2012) Judith Nicholson et al.   JOURNAL OF PROTEOME RESEARCH

Distinct Regulatory Mechanisms and Functions for p53-Activated and p53-Repressed DNA Damage Response Genes in Embryonic Stem Cells

(2012) Mangmang Li et al.   MOLECULAR CELL

Oncosuppressive role of p53-induced miR-205 in triple negative breast cancer

(2012) Claudia Piovan et al.   Molecular Oncology

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Identification of Kinases Regulating Prostate Cancer Cell Growth Using an RNAi Phenotypic Screen

(2012) Hilary Whitworth et al.   PLoS One

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

The p53 response element and transcriptional repression

(2011) Bei Wang et al.   CELL CYCLE

miR-34a Induces the Downregulation of Both E2F1 and B-Myb Oncogenes in Leukemic Cells

(2011) G. Zauli et al.   CLINICAL CANCER RESEARCH

Genomic Loss of miR-486 Regulates Tumor Progression and the OLFM4 Antiapoptotic Factor in Gastric Cancer

(2011) H.-K. Oh et al.   CLINICAL CANCER RESEARCH

p53-dependent Induction ofPVT1and miR-1204

(2011) Anthony M. Barsotti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial–mesenchymal transition

(2011) Nam Hee Kim et al.   JOURNAL OF CELL BIOLOGY

p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2

(2011) Taewan Kim et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

The functional role of long non-coding RNA in human carcinomas

(2011) Ewan A Gibb et al.   Molecular Cancer

Restitution of Tumor Suppressor MicroRNAs Using a Systemic Nanovector Inhibits Pancreatic Cancer Growth in Mice

(2011) D. Pramanik et al.   MOLECULAR CANCER THERAPEUTICS

Diagnostic performance of the PCA3 urine test

(2011) George Leighton Lee et al.   Nature Reviews Urology

Inferring transcription factor complexes from ChIP-seq data

(2011) Tom Whitington et al.   NUCLEIC ACIDS RESEARCH

Identifying transcriptional start sites of human microRNAs based on high-throughput sequencing data

(2011) Chia-Hung Chien et al.   NUCLEIC ACIDS RESEARCH

Urine TMPRSS2:ERG Fusion Transcript Stratifies Prostate Cancer Risk in Men with Elevated Serum PSA

(2011) S. A. Tomlins et al.   Science Translational Medicine

To repress or not to repress: This is the guardian's question

(2011) John L. Rinn et al.   TRENDS IN CELL BIOLOGY

The Emergence of lncRNAs in Cancer Biology

(2011) J. R. Prensner et al.   Cancer Discovery

High-mobility group box 1 and cancer

(2010) Daolin Tang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

C/EBP  regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations

(2010) J. A. Pulikkan et al.   BLOOD

Development of a Lung Cancer Therapeutic Based on the Tumor Suppressor MicroRNA-34

(2010) J. F. Wiggins et al.   CANCER RESEARCH

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

(2010) Maite Huarte et al.   CELL

Large non-coding RNAs: missing links in cancer?

(2010) M. Huarte et al.   HUMAN MOLECULAR GENETICS

GATA3 Inhibits Breast Cancer Metastasis through the Reversal of Epithelial-Mesenchymal Transition

(2010) Wei Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNA interference targeting CITRON can significantly inhibit the proliferation of hepatocellular carcinoma cells

(2010) Yinghui Fu et al.   MOLECULAR BIOLOGY REPORTS

Nanoparticles Modified With Tumor-targeting scFv Deliver siRNA and miRNA for Cancer Therapy

(2010) Yunching Chen et al.   MOLECULAR THERAPY

GATA-1 associates with and inhibits p53

(2009) C. D. Trainor et al.   BLOOD

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

The miR-34 family in cancer and apoptosis

(2009) H Hermeking   CELL DEATH AND DIFFERENTIATION

Krüppel-like factor 12 plays a significant role in poorly differentiated gastric cancer progression

(2009) Yu Nakamura et al.   INTERNATIONAL JOURNAL OF CANCER

Modulation of microRNA processing by p53

(2009) Hiroshi I. Suzuki et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

MEME SUITE: tools for motif discovery and searching

(2009) T. L. Bailey et al.   NUCLEIC ACIDS RESEARCH

p53 represses c-Myc through induction of the tumor suppressor miR-145

(2009) M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Coordinated Regulation of Cell Cycle Transcripts by p53-Inducible microRNAs, miR-192 and miR-215

(2008) S. A. Georges et al.   CANCER RESEARCH

p53-Responsive MicroRNAs 192 and 215 Are Capable of Inducing Cell Cycle Arrest

(2008) C. J. Braun et al.   CANCER RESEARCH

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Quantitative Proteomics Analysis of the Effects of Ionizing Radiation in Wild Type and p53K317RKnock-in Mouse Thymocytes

(2008) Lisa M. Miller Jenkins et al.   MOLECULAR & CELLULAR PROTEOMICS

Cooperation of Gata3, c-Myc and Notch in malignant transformation of double positive thymocytes

(2008) Jan Piet van Hamburg et al.   MOLECULAR IMMUNOLOGY

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

Transcriptional control of human p53-regulated genes

(2008) Todd Riley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

CDK1 promotes cell proliferation and survival via phosphorylation and inhibition of FOXO1 transcription factor

(2008) P Liu et al.   ONCOGENE

Global analysis of cellular protein translation by pulsed SILAC

(2008) Björn Schwanhäusser et al.   PROTEOMICS