Inhibition of stress-induced hepatic tryptophan 2,3-dioxygenase exhibits antidepressant activity in an animal model of depressive behaviour

Citalopram decreases tryptophan 2,3-dioxygenase activity and brain 5-HT turnover in swim stressed rats

(2014) Iffat Ara et al.   Pharmacological Reports

NMDA Receptor Blockade by Ketamine Abrogates Lipopolysaccharide-Induced Depressive-Like Behavior in C57BL/6J Mice

(2013) Adam K Walker et al.   NEUROPSYCHOPHARMACOLOGY

Effects of chronic treatment with corticosterone and imipramine on fos immunoreactivity and adult hippocampal neurogenesis

(2012) L. Diniz et al.   BEHAVIOURAL BRAIN RESEARCH

Poly I:C-induced activation of the immune response is accompanied by depression and anxiety-like behaviours, kynurenine pathway activation and reduced BDNF expression

(2012) Sinead M. Gibney et al.   BRAIN BEHAVIOR AND IMMUNITY

The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes

(2012) Wouter Beumer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A randomized controlled trial of allopurinol vs. placebo added on to antipsychotics in patients with schizophrenia or schizoaffective disorder

(2012) Mark Weiser et al.   SCHIZOPHRENIA RESEARCH

Repeated Short-term (2h×14d) Emotional Stress Induces Lasting Depression-like Behavior in Mice

(2012) Kyoung-Shim Kim et al.   Experimental Neurobiology

Changes in kynurenine pathway metabolism in the brain, liver and kidney of aged female Wistar rats

(2011) Nady Braidy et al.   FEBS Journal

Interleukin-1β: A New Regulator of the Kynurenine Pathway Affecting Human Hippocampal Neurogenesis

(2011) Patricia A Zunszain et al.   NEUROPSYCHOPHARMACOLOGY

Time-course of hippocampal granule cell degeneration and changes in adult neurogenesis after adrenalectomy in rats

(2011) S.C. Spanswick et al.   NEUROSCIENCE

Deletion of forebrain glucocorticoid receptors impairs neuroendocrine stress responses and induces depression-like behavior in males but not females

(2011) M.B. Solomon et al.   NEUROSCIENCE

Chronic restraint stress in adolescence differentially influences hypothalamic-pituitary-adrenal axis function and adult hippocampal neurogenesis in male and female rats

(2010) Cindy K. Barha et al.   HIPPOCAMPUS

Allopurinol for Treatment-Resistant Schizophrenia and Epilepsy: A Case Report

(2010) C.-S. Liang et al.   PHARMACOPSYCHIATRY

Psychological Stress-Induced, IDO1-Dependent Tryptophan Catabolism: Implications on Immunosuppression in Mice and Humans

(2010) Cornelia Kiank et al.   PLoS One

Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus

(2010) Koji Ohira et al.   Molecular Brain

Exposure to enriched environment restores the survival and differentiation of new born cells in the hippocampus and ameliorates depressive symptoms in chronically stressed rats

(2009) J. Veena et al.   NEUROSCIENCE LETTERS

Identification and characterization of novel variants of the tryptophan 2,3-dioxygenase gene: Differential regulation in the mouse nervous system during development

(2009) Masaaki Kanai et al.   NEUROSCIENCE RESEARCH

A role for serotonin in the antidepressant activity of NG-Nitro-L-arginine, in the rat forced swimming test

(2009) Valentina Gigliucci et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

A double-blind trial of adjunctive allopurinol for schizophrenia

(2009) Faith B. Dickerson et al.   SCHIZOPHRENIA RESEARCH

Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice

(2009) Masaaki Kanai et al.   Molecular Brain

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

(2008) J C O'Connor et al.   MOLECULAR PSYCHIATRY

Alterations in kynurenine precursor and product levels in schizophrenia and bipolar disorder

(2008) Christine L. Miller et al.   NEUROCHEMISTRY INTERNATIONAL

Induction of indolamine 2,3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: A role for IFN-γ?

(2008) Thomas J. Connor et al.   NEUROSCIENCE LETTERS

Reduced efficacy of fluoxetine following MDMA (“Ecstasy”)-induced serotonin loss in rats

(2008) Sarah Durkin et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY