Psychological Stress-Induced, IDO1-Dependent Tryptophan Catabolism: Implications on Immunosuppression in Mice and Humans

Enhanced Indoleamine 2,3‐Dioxygenase Activity in Patients with Severe Sepsis and Septic Shock

(2010) Pierre Tattevin et al.   JOURNAL OF INFECTIOUS DISEASES

Tryptophan Catabolism by Indoleamine 2,3-Dioxygenase 1 Alters the Balance of TH17 to Regulatory T Cells in HIV Disease

(2010) D. Favre et al.   Science Translational Medicine

HIGH ACTIVITY OF INDOLEAMINE 2,3 DIOXYGENASE ENZYME PREDICTS DISEASE SEVERITY AND CASE FATALITY IN BACTEREMIC PATIENTS

(2010) Reetta Huttunen et al.   SHOCK

Chronic Stress and Individual Vulnerability

(2009) Mathias V. Schmidt et al.   Annals of the New York Academy of Sciences

65. Proinflammatory cytokines mediate acute stress-induced loss of intestinal barrier function in the terminal ileum which enhances tryptophan catabolism in BALB/C mice

(2009) C. Kiank et al.   BRAIN BEHAVIOR AND IMMUNITY

Mood and cortisol responses following tryptophan-rich hydrolyzed protein and acute stress in healthy subjects with high and low cognitive reactivity to depression

(2009) Christine Firk et al.   CLINICAL NUTRITION

Interferon-γ-Responsive Nonhematopoietic Cells Regulate the Immune Response to Mycobacterium tuberculosis

(2009) Ludovic Desvignes et al.   IMMUNITY

Intestinal barrier function: Molecular regulation and disease pathogenesis

(2009) Katherine R. Groschwitz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Indoleamine 2,3-Dioxygenase Tissue Distribution and Cellular Localization in Mice: Implications for Its Biological Functions

(2009) Xiangchen Dai et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Tryptophan Deprivation Induces Inhibitory Receptors ILT3 and ILT4 on Dendritic Cells Favoring the Induction of Human CD4+CD25+ Foxp3+ T Regulatory Cells

(2009) M. Brenk et al.   JOURNAL OF IMMUNOLOGY

Interferon-  and Tumor Necrosis Factor-  Mediate the Upregulation of Indoleamine 2,3-Dioxygenase and the Induction of Depressive-Like Behavior in Mice in Response to Bacillus Calmette-Guerin

(2009) J. C. O'Connor et al.   JOURNAL OF NEUROSCIENCE

CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-α: relationship to CNS immune responses and depression

(2009) C L Raison et al.   MOLECULAR PSYCHIATRY

Enhancing versus Suppressive Effects of Stress on Immune Function: Implications for Immunoprotection and Immunopathology

(2009) Firdaus S. Dhabhar   NEUROIMMUNOMODULATION

Acute tryptophan depletion evokes negative mood in healthy females who have previously experienced concurrent negative mood and tryptophan depletion

(2009) Oliver J. Robinson et al.   PSYCHOPHARMACOLOGY

INCREASED PLASMA KYNURENINE VALUES AND KYNURENINE-TRYPTOPHAN RATIOS AFTER MAJOR TRAUMA ARE EARLY INDICATORS FOR THE DEVELOPMENT OF SEPSIS

(2009) Tim T. Lögters et al.   SHOCK

Tryptophan as an evolutionarily conserved signal to brain serotonin: Molecular evidence and psychiatric implications

(2009) Sascha Russo et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Chronic peripheral administration of corticotropin-releasing factor causes colonic barrier dysfunction similar to psychological stress

(2008) Aaron A. Teitelbaum et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Micromolar concentration of kynurenic acid in rat small intestine

(2008) D. Kuc et al.   AMINO ACIDS

High concentration of kynurenic acid in bile and pancreatic juice

(2008) Piotr Paluszkiewicz et al.   AMINO ACIDS

The role of indoleamine 2,3-dioxygenase in the induction of immune tolerance: focus on hematology

(2008) A. Curti et al.   BLOOD

Pneumonia as a long-term consequence of chronic psychological stress in BALB/c mice

(2008) Cornelia Kiank et al.   BRAIN BEHAVIOR AND IMMUNITY

Coping style and immunity in animals: Making sense of individual variation

(2008) J.M. Koolhaas   BRAIN BEHAVIOR AND IMMUNITY

Hypermetabolic Syndrome as a Consequence of Repeated Psychological Stress in Mice

(2008) Maren Depke et al.   ENDOCRINOLOGY

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

(2008) J C O'Connor et al.   MOLECULAR PSYCHIATRY

Induction of indolamine 2,3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: A role for IFN-γ?

(2008) Thomas J. Connor et al.   NEUROSCIENCE LETTERS

Stress neuropeptides evoke epithelial responses via mast cell activation in the rat colon

(2008) Javier Santos et al.   PSYCHONEUROENDOCRINOLOGY

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE