Factors Associated with Heritable Pulmonary Arterial Hypertension Exert Convergent Actions on the miR-130/301-Vascular Matrix Feedback Loop

PPARγ agonist pioglitazone reverses pulmonary hypertension and prevents right heart failure via fatty acid oxidation

(2018) Ekaterina Legchenko et al.   Science Translational Medicine

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

(2018) Stefan Gräf et al.   Nature Communications

DNA Damage and Pulmonary Hypertension

(2016) Benoît Ranchoux et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis

(2016) Ting Xie et al.   JOURNAL OF CLINICAL INVESTIGATION

Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension

(2016) Thomas Bertero et al.   JOURNAL OF CLINICAL INVESTIGATION

Expansion of the Gene Ontology knowledgebase and resources

(2016)   NUCLEIC ACIDS RESEARCH

KEGG: new perspectives on genomes, pathways, diseases and drugs

(2016) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Complex inheritance in Pulmonary Arterial Hypertension patients with several mutations

(2016) Guillermo Pousada et al.   Scientific Reports

The Reactome pathway Knowledgebase

(2015) Antonio Fabregat et al.   NUCLEIC ACIDS RESEARCH

A YAP/TAZ-miR-130/301 molecular circuit exerts systems-level control of fibrosis in a network of human diseases and physiologic conditions

(2015) Thomas Bertero et al.   Scientific Reports

Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit

(2015) Thomas Bertero et al.   Cell Reports

The Metabolic Basis of Pulmonary Arterial Hypertension

(2014) Gopinath Sutendra et al.   Cell Metabolism

The Genetics of Pulmonary Arterial Hypertension

(2014) Eric D. Austin et al.   CIRCULATION RESEARCH

Sox17 is required for normal pulmonary vascular morphogenesis

(2014) Alexander W. Lange et al.   DEVELOPMENTAL BIOLOGY

The MicroRNA-130/301 Family Controls Vasoconstriction in Pulmonary Hypertension

(2014) Thomas Bertero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension

(2014) Thomas Bertero et al.   JOURNAL OF CLINICAL INVESTIGATION

An evidence-based knowledgebase of pulmonary arterial hypertension to identify genes and pathways relevant to pathogenesis

(2014) Min Zhao et al.   Molecular BioSystems

MatrixDB, the extracellular matrix interaction database: updated content, a new navigator and expanded functionalities

(2014) G. Launay et al.   NUCLEIC ACIDS RESEARCH

The BioGRID interaction database: 2015 update

(2014) Andrew Chatr-aryamontri et al.   NUCLEIC ACIDS RESEARCH

Role for DNA Damage Signaling in Pulmonary Arterial Hypertension

(2013) Jolyane Meloche et al.   CIRCULATION

TBX4mutations (small patella syndrome) are associated with childhood-onset pulmonary arterial hypertension

(2013) Wilhelmina S Kerstjens-Frederikse et al.   JOURNAL OF MEDICAL GENETICS

Updated Clinical Classification of Pulmonary Hypertension

(2013) Gerald Simonneau et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension

(2013) Marine Germain et al.   NATURE GENETICS

EIF2AK4 mutations cause pulmonary veno-occlusive disease, a recessive form of pulmonary hypertension

(2013) Mélanie Eyries et al.   NATURE GENETICS

A Novel Channelopathy in Pulmonary Arterial Hypertension

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

The MIntAct project—IntAct as a common curation platform for 11 molecular interaction databases

(2013) Sandra Orchard et al.   NUCLEIC ACIDS RESEARCH

The Reactome pathway knowledgebase

(2013) David Croft et al.   NUCLEIC ACIDS RESEARCH

Sox17 is indispensable for acquisition and maintenance of arterial identity

(2013) Monica Corada et al.   Nature Communications

InnateDB: systems biology of innate immunity and beyond—recent updates and continuing curation

(2012) Karin Breuer et al.   NUCLEIC ACIDS RESEARCH

Abnormal Pulmonary Artery Stiffness in Pulmonary Arterial Hypertension: In Vivo Study with Intravascular Ultrasound

(2012) Edmund M. T. Lau et al.   PLoS One

Multiple Roles and Interactions of Tbx4 and Tbx5 in Development of the Respiratory System

(2012) Ripla Arora et al.   PLoS Genetics

Persistent vascular collagen accumulation alters hemodynamic recovery from chronic hypoxia

(2011) Diana M. Tabima et al.   JOURNAL OF BIOMECHANICS

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

MINT, the molecular interaction database: 2012 update

(2011) Luana Licata et al.   NUCLEIC ACIDS RESEARCH

The protective role of adiponectin in pulmonary vascular disease

(2009) Georg Hansmann et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

CORUM: the comprehensive resource of mammalian protein complexes—2009

(2009) Andreas Ruepp et al.   NUCLEIC ACIDS RESEARCH

Insulin resistance in pulmonary arterial hypertension

(2008) R. T. Zamanian et al.   EUROPEAN RESPIRATORY JOURNAL

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Pulmonary vascular input impedance is a combined measure of pulmonary vascular resistance and stiffness and predicts clinical outcomes better than pulmonary vascular resistance alone in pediatric patients with pulmonary hypertension

(2007) Kendall S. Hunter et al.   AMERICAN HEART JOURNAL

Pathogenic mechanisms of pulmonary arterial hypertension

(2007) Stephen Y. Chan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY