Hypoxic Signaling During Tissue Repair and Regenerative Medicine

The Use of Adipose Mesenchymal Stem Cells and Human Umbilical Vascular Endothelial Cells on a Fibrin Matrix for Endothelialized Skin Substitute

(2015) Isabel Sánchez-Muñoz et al.   TISSUE ENGINEERING PART A

Direct measurement of local oxygen concentration in the bone marrow of live animals

(2014) Joel A. Spencer et al.   NATURE

The Role of Hypoxia-Inducible Factor in Wound Healing

(2014) Wan Xing Hong et al.   Advances in Wound Care

Epidermal Deletion of HIF-2α Stimulates Wound Closure

(2013) Andrew S. Cowburn et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Concerted inhibition of HIF-1α and -2α expression markedly suppresses angiogenesis in cultured RPE cells

(2013) Takeshi Nakajima et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Nrf2 acts cell-autonomously in endothelium to regulate tip cell formation and vascular branching

(2013) Y. Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endothelial HIF-2α regulates murine pathological angiogenesis and revascularization processes

(2012) Nicolas Skuli et al.   JOURNAL OF CLINICAL INVESTIGATION

Tie2-dependent knockout of HIF-1 impairs burn wound vascularization and homing of bone marrow-derived angiogenic cells

(2011) Kakali Sarkar et al.   CARDIOVASCULAR RESEARCH

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

Roles of the human hypoxia-inducible factor (HIF)-3α variants in the hypoxia response

(2011) Minna Heikkilä et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Aging impairs the mobilization and homing of bone marrow-derived angiogenic cells to burn wounds

(2011) Xianjie Zhang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Normalization of the Vasculature for Treatment of Cancer and Other Diseases

(2011) Shom Goel et al.   PHYSIOLOGICAL REVIEWS

From Vessel Sprouting to Normalization

(2010) Cathy Coulon et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Int6 /eIF3e Silencing Promotes Functional Blood Vessel Outgrowth and Enhances Wound Healing by Upregulating Hypoxia-Induced Factor 2α Expression

(2010) Li Chen et al.   CIRCULATION

Hypoxia-inducible factor 2α regulates macrophage function in mouse models of acute and tumor inflammation

(2010) Hongxia Z. Imtiyaz et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypoxia inducible microRNA 210 attenuates keratinocyte proliferation and impairs closure in a murine model of ischemic wounds

(2010) S. Biswas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired angiogenesis and mobilization of circulating angiogenic cells in HIF-1α heterozygous-null mice after burn wounding

(2010) Xianjie Zhang et al.   WOUND REPAIR AND REGENERATION

Therapeutic Manipulation of the HIF Hydroxylases

(2009) Simon Nagel et al.   ANTIOXIDANTS & REDOX SIGNALING

Vascular Responses to Hypoxia and Ischemia

(2009) Gregg L. Semenza   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The humanHIF(hypoxia-inducible factor)-3α gene is a HIF-1 target gene and may modulate hypoxic gene induction

(2009) Tetsuhiro Tanaka et al.   BIOCHEMICAL JOURNAL

Endothelial deletion of hypoxia-inducible factor-2  (HIF-2 ) alters vascular function and tumor angiogenesis

(2009) N. Skuli et al.   BLOOD

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues

(2009) H. Thangarajah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIF2  inhibition promotes p53 pathway activity, tumor cell death, and radiation responses

(2009) J. A. Bertout et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anthracycline chemotherapy inhibits HIF-1 transcriptional activity and tumor-induced mobilization of circulating angiogenic cells

(2009) K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Effect of Hypoxia on In Vitro Prevascularization of a Thick Soft Tissue

(2009) Craig K. Griffith et al.   TISSUE ENGINEERING PART A

Turn me on: regulating HIF transcriptional activity

(2008) K Lisy et al.   CELL DEATH AND DIFFERENTIATION

Age-dependent impairment of HIF-1α expression in diabetic mice: Correction with electroporation-facilitated gene therapy increases wound healing, angiogenesis, and circulating angiogenic cells

(2008) Lixin Liu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL

Stabilization of HIF-1  is critical to improve wound healing in diabetic mice

(2008) I. R. Botusan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Effect of Matrix Density on the Regulation of 3-D Capillary Morphogenesis

(2007) Cyrus M. Ghajar et al.   BIOPHYSICAL JOURNAL