Elucidating Pharmacological Mechanisms of Natural Medicines by Biclustering Analysis of the Gene Expression Profile: A Case Study on Curcumin and Si-Wu-Tang

Curcumin, a component of golden spice: From bedside to bench and back

(2014) Sahdeo Prasad et al.   BIOTECHNOLOGY ADVANCES

Elucidating Polypharmacological Mechanisms of Polyphenols by Gene Module Profile Analysis

(2014) Bin Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tanshinone I Activates the Nrf2-Dependent Antioxidant Response and Protects Against As(III)-Induced Lung Inflammation In Vitro and In Vivo

(2013) Shasha Tao et al.   ANTIOXIDANTS & REDOX SIGNALING

Identification of transcription factors for drug-associated gene modules and biomedical implications

(2013) Min Xiong et al.   BIOINFORMATICS

Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding

(2013) M. Iskar et al.   Molecular Systems Biology

Targeting Nrf2-Mediated Gene Transcription by Extremely Potent Synthetic Triterpenoids Attenuate Dopaminergic Neurotoxicity in the MPTP Mouse Model of Parkinson's Disease

(2012) Navneet Ammal Kaidery et al.   ANTIOXIDANTS & REDOX SIGNALING

Discovery of Molecular Mechanisms of Traditional Chinese Medicinal Formula Si-Wu-Tang Using Gene Expression Microarray and Connectivity Map

(2011) Zhining Wen et al.   PLoS One

Participation of covalent modification of Keap1 in the activation of Nrf2 by tert-butylbenzoquinone, an electrophilic metabolite of butylated hydroxyanisole

(2011) Yumi Abiko et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

FABIA: factor analysis for bicluster acquisition

(2010) Sepp Hochreiter et al.   BIOINFORMATICS

Application of bioactivity database of Chinese herbal medicine on the therapeutic prediction, drug development, and safety evaluation

(2010) Hui-Man Cheng et al.   JOURNAL OF ETHNOPHARMACOLOGY

Network-Based Elucidation of Human Disease Similarities Reveals Common Functional Modules Enriched for Pluripotent Drug Targets

(2010) Silpa Suthram et al.   PLoS Computational Biology

Natural products and drug discovery. Can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia?

(2009) Hong-Fang Ji et al.   EMBO REPORTS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Relationship Between San-Huang-Xie-Xin-Tang and Its Herbal Components on the Gene Expression Profiles in HepG2 Cells

(2008) Wen-Yu Cheng et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Curcumin Restores Corticosteroid Function in Monocytes Exposed to Oxidants by Maintaining HDAC2

(2008) Koremu K. Meja et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

DrugBank and its relevance to pharmacogenomics

(2008) David S Wishart   PHARMACOGENOMICS

Curcumin: Preventive and Therapeutic Properties in Laboratory Studies and Clinical Trials

(2007) Alexios S. Strimpakos et al.   ANTIOXIDANTS & REDOX SIGNALING