Survivin as a Preferential Target for Cancer Therapy

HER2 stabilizes survivin while concomitantly down-regulating survivin gene transcription by suppressing Notch cleavage

(2013) Ji-hyun Ju et al.   BIOCHEMICAL JOURNAL

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

(2013) Thomas Gaj et al.   TRENDS IN BIOTECHNOLOGY

Notch-1 signaling facilitates survivin expression in human non-small cell lung cancer cells

(2011) Yuqing Chen et al.   CANCER BIOLOGY & THERAPY

Genome Engineering With Zinc-Finger Nucleases

(2011) Dana Carroll   GENETICS

Caspase 3–mediated stimulation of tumor cell repopulation during cancer radiotherapy

(2011) Qian Huang et al.   NATURE MEDICINE

EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells

(2010) Haijuan Wang et al.   BMC MOLECULAR BIOLOGY

Targeting DNA Double-Strand Breaks with TAL Effector Nucleases

(2010) M. Christian et al.   GENETICS

Acetylation Directs Survivin Nuclear Localization to Repress STAT3 Oncogenic Activity

(2010) Haijuan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Improved nonviral cancer suicide gene therapy using survivin promoter-driven mutant Bax

(2009) H Garg et al.   CANCER GENE THERAPY

 -Secretase Inhibitors Abrogate Oxaliplatin-Induced Activation of the Notch-1 Signaling Pathway in Colon Cancer Cells Resulting in Enhanced Chemosensitivity

(2009) R. D. Meng et al.   CANCER RESEARCH

Fractalkine has anti-apoptotic and proliferative effects on human vascular smooth muscle cells via epidermal growth factor receptor signalling

(2009) Gemma E. White et al.   CARDIOVASCULAR RESEARCH

Expression of HER-2 in MCF-7 breast cancer cells modulates anti-apoptotic proteins Survivin and Bcl-2 via the extracellular signal-related kinase (ERK) and phosphoinositide-3 kinase (PI3K) signalling pathways

(2008) Aisha Siddiqa et al.   BMC CANCER

Altered Cytoplasmic-to-Nuclear Ratio of Survivin Is a Prognostic Indicator in Breast Cancer

(2008) D. J. Brennan et al.   CLINICAL CANCER RESEARCH

Nuclear survivin in pN2 nonsmall cell lung cancer: prognostic and clinical implications

(2008) S. Mohamed et al.   EUROPEAN RESPIRATORY JOURNAL

Nuclear survivin expression predicts poorer prognosis in glioblastoma

(2008) Katsuyuki Shirai et al.   JOURNAL OF NEURO-ONCOLOGY

The role of survivin on overall survival of non-small cell lung cancer, a meta-analysis of published literatures

(2008) Jiang Fan et al.   LUNG CANCER

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Survivin gene RNA interference inhibits proliferation, induces apoptosis, and enhances radiosensitivity in HeLa cells

(2006) Hui Song et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology