HER2 stabilizes survivin while concomitantly down-regulating survivin gene transcription by suppressing Notch cleavage

Notch-1 signaling facilitates survivin expression in human non-small cell lung cancer cells

(2011) Yuqing Chen et al.   CANCER BIOLOGY & THERAPY

Assembly of the presenilin γ-/ε-secretase complex

(2011) P. St George-Hyslop et al.   JOURNAL OF NEUROCHEMISTRY

EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells

(2010) Haijuan Wang et al.   BMC MOLECULAR BIOLOGY

A survivin double point mutant has potent inhibitory effect on the growth of hepatocellular cancer cells

(2010) Rui Zhang et al.   CANCER BIOLOGY & THERAPY

Akt isoform-specific inhibition of MDA-MB-231 cell proliferation

(2010) Wonseok Yang et al.   CELLULAR SIGNALLING

Role for X-linked Inhibitor of Apoptosis Protein Upstream of Mitochondrial Permeabilization

(2009) Thomas W. Owens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of HER-2 in MCF-7 breast cancer cells modulates anti-apoptotic proteins Survivin and Bcl-2 via the extracellular signal-related kinase (ERK) and phosphoinositide-3 kinase (PI3K) signalling pathways

(2008) Aisha Siddiqa et al.   BMC CANCER

Down-regulation of Notch-dependent transcription by Akt in vitro

(2008) Jieun Song et al.   FEBS LETTERS

EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer

(2008) Vihren Kolev et al.   NATURE CELL BIOLOGY

ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a γ-secretase inhibitor

(2008) C Osipo et al.   ONCOGENE