The Role of Mitochondrial DNA Damage and Repair in the Resistance of BCR/ABL-Expressing Cells to Tyrosine Kinase Inhibitors
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Role of Mitochondrial DNA Damage and Repair in the Resistance of BCR/ABL-Expressing Cells to Tyrosine Kinase Inhibitors
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 14, Issue 8, Pages 16348-16364
Publisher
MDPI AG
Online
2013-08-07
DOI
10.3390/ijms140816348
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Chronic myeloid leukemia stem cells in the era of targeted therapies: resistance, persistence and long-term dormancy
- (2015) Jean-Claude Chomel et al. Oncotarget
- Characterization and prognostic significance of mitochondrial DNA variations in acute myeloid leukemia
- (2013) Trine Silkjaer et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Mitochondrial genome depletion in human liver cells abolishes bile acid-induced apoptosis: Role of the Akt/mTOR survival pathway and Bcl-2 family proteins
- (2013) Jose J.G. Marin et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mitochondrial and Nuclear DNA Damage and Repair in Age-Related Macular Degeneration
- (2013) Janusz Blasiak et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- BCR-ABL1 RT-qPCR for Monitoring the Molecular Response to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia
- (2013) Richard D. Press et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Rac2-MRC-cIII-generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors
- (2012) M. Nieborowska-Skorska et al. BLOOD
- Generation, function and diagnostic value of mitochondrial DNA copy number alterations in human cancers
- (2011) Man Yu LIFE SCIENCES
- Exploiting Mitochondrial Dysfunction for Effective Elimination of Imatinib-Resistant Leukemic Cells
- (2011) Jérome Kluza et al. PLoS One
- Enhancement of imatinib-induced apoptosis of BCR/ABL-expressing cells by nutlin-3 through synergistic activation of the mitochondrial apoptotic pathway
- (2010) Tetsuya Kurosu et al. APOPTOSIS
- Apoptogenic factors released from mitochondria
- (2010) David L. Vaux BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Aerobic Glycolysis Suppresses p53 Activity to Provide Selective Protection from Apoptosis upon Loss of Growth Signals or Inhibition of BCR-Abl
- (2010) E. F. Mason et al. CANCER RESEARCH
- Mitochondrial DNA repair and association with aging – An update
- (2010) Ricardo Gredilla et al. EXPERIMENTAL GERONTOLOGY
- Reactive oxygen species, cellular redox systems, and apoptosis
- (2010) Magdalena L. Circu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Chronic myeloid leukemia: mechanisms of blastic transformation
- (2010) Danilo Perrotti et al. JOURNAL OF CLINICAL INVESTIGATION
- The causes of cancer revisited: “Mitochondrial malignancy” and ROS-induced oncogenic transformation – Why mitochondria are targets for cancer therapy
- (2010) Stephen J. Ralph et al. MOLECULAR ASPECTS OF MEDICINE
- Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1α-induced metabolic reprograming
- (2010) F Zhao et al. ONCOGENE
- BMS-214662 induces mitochondrial apoptosis in chronic myeloid leukemia (CML) stem/progenitor cells, including CD34+38- cells, through activation of protein kinase C
- (2009) F. Pellicano et al. BLOOD
- Time-dependent effects of imatinib in human leukaemia cells: a kinetic NMR-profiling study
- (2009) J Klawitter et al. BRITISH JOURNAL OF CANCER
- Sorafenib Induces Apoptosis Specifically in Cells Expressing BCR/ABL by Inhibiting Its Kinase Activity to Activate the Intrinsic Mitochondrial Pathway
- (2009) T. Kurosu et al. CANCER RESEARCH
- Abnormalities in Glucose Uptake and Metabolism in Imatinib-Resistant Human BCR-ABL-Positive Cells
- (2009) D. J. Kominsky et al. CLINICAL CANCER RESEARCH
- Novel DNA mismatch-repair activity involving YB-1 in human mitochondria
- (2009) Nadja C. de Souza-Pinto et al. DNA REPAIR
- A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis
- (2009) J. S. Park et al. HUMAN MOLECULAR GENETICS
- Translation of the Philadelphia chromosome into therapy for CML
- (2008) B. J. Druker BLOOD
- A prospective study of mitochondrial DNA copy number and risk of non-Hodgkin lymphoma
- (2008) Q. Lan et al. BLOOD
- Transient Potent BCR-ABL Inhibition Is Sufficient to Commit Chronic Myeloid Leukemia Cells Irreversibly to Apoptosis
- (2008) Neil P. Shah et al. CANCER CELL
- DNA-damage repair; the good, the bad, and the ugly
- (2008) Razqallah Hakem EMBO JOURNAL
- Effective killing of Gleevec-resistant CML cells with T315I mutation by a natural compound PEITC through redox-mediated mechanism
- (2008) H Zhang et al. LEUKEMIA
- Reversible regulation of metastasis by ROS-generating mtDNA mutations
- (2008) Kaori Ishikawa et al. MITOCHONDRION
- Removal of Oxidative DNA Damage via FEN1-Dependent Long-Patch Base Excision Repair in Human Cell Mitochondria
- (2008) P. Liu et al. MOLECULAR AND CELLULAR BIOLOGY
- Quantitative Analysis of Pathways Controlling Extrinsic Apoptosis in Single Cells
- (2008) John G. Albeck et al. MOLECULAR CELL
- Apoptosis: controlled demolition at the cellular level
- (2007) Rebecca C. Taylor et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started