Type 3 innate lymphoid cells producing IL-17 and IL-22 are expanded in the gut, in the peripheral blood, synovial fluid and bone marrow of patients with ankylosing spondylitis

Ustekinumab for the treatment of patients with active ankylosing spondylitis: results of a 28-week, prospective, open-label, proof-of-concept study (TOPAS)

(2014) Denis Poddubnyy et al.   ANNALS OF THE RHEUMATIC DISEASES

Efficacy of TNFα blockers in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: a meta-analysis

(2014) Johanna Callhoff et al.   ANNALS OF THE RHEUMATIC DISEASES

Human innate lymphoid cells

(2014) M. D. Hazenberg et al.   BLOOD

Relevance of the gut/joint axis for the management of spondyloarthritis in daily clinical practice

(2014) Heleen Cypers et al.   CURRENT OPINION IN RHEUMATOLOGY

Microbiota-Dependent Crosstalk Between Macrophages and ILC3 Promotes Intestinal Homeostasis

(2014) A. Mortha et al.   SCIENCE

Adaptation of Innate Lymphoid Cells to a Micronutrient Deficiency Promotes Type 2 Barrier Immunity

(2014) S. P. Spencer et al.   SCIENCE

Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation

(2013) Francesco Ciccia et al.   ANNALS OF THE RHEUMATIC DISEASES

Degree of bone marrow oedema in sacroiliac joints of patients with axial spondyloarthritis is linked to gut inflammation and male sex: results from the GIANT cohort

(2013) Liesbet Van Praet et al.   ANNALS OF THE RHEUMATIC DISEASES

Identification of a cellular ligand for the natural cytotoxicity receptor NKp44

(2013) F. Baychelier et al.   BLOOD

α4β7integrin: beyond T cell trafficking

(2013) Sarah L Kempster et al.   GUT

ILC1 Populations Join the Border Patrol

(2013) Kevin J. Maloy et al.   IMMUNITY

Group 3 Innate Lymphoid Cells Inhibit T-Cell-Mediated Intestinal Inflammation through Aryl Hydrocarbon Receptor Signaling and Regulation of Microflora

(2013) Ju Qiu et al.   IMMUNITY

RORγt+ Innate Lymphoid Cells Acquire a Proinflammatory Program upon Engagement of the Activating Receptor NKp44

(2013) Timor Glatzer et al.   IMMUNITY

A T-bet gradient controls the fate and function of CCR6−RORγt+ innate lymphoid cells

(2013) Christoph S. N. Klose et al.   NATURE

The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway

(2013) Lucille C Rankin et al.   NATURE IMMUNOLOGY

Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues

(2013) Jochem H Bernink et al.   NATURE IMMUNOLOGY

Aryl hydrocarbon receptor promotes RORγt+ Group 3 ILCs and controls intestinal immunity and inflammation

(2013) Ju Qiu et al.   Seminars in Immunopathology

Review: The Interleukin-23/Interleukin-17 Axis in Spondyloarthritis Pathogenesis: Th17 and Beyond

(2013) Judith A. Smith et al.   Arthritis & Rheumatology

IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4−CD8− entheseal resident T cells

(2012) Jonathan P Sherlock et al.   NATURE MEDICINE

Interleukin-22 and interleukin-22-producing NKp44+ natural killer cells in subclinical gut inflammation in ankylosing spondylitis

(2011) Francesco Ciccia et al.   ARTHRITIS AND RHEUMATISM

CCR6 identifies lymphoid tissue inducer cells within cryptopatches

(2010) A. Lügering et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Human NKp44+IL-22+cells and LTi-like cells constitute a stable RORC+lineage distinct from conventional natural killer cells

(2010) Natasha K. Crellin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Overexpression of interleukin-23, but not interleukin-17, as an immunologic signature of subclinical intestinal inflammation in ankylosing spondylitis

(2009) Francesco Ciccia et al.   ARTHRITIS AND RHEUMATISM

Microbial Flora Drives Interleukin 22 Production in Intestinal NKp46+ Cells that Provide Innate Mucosal Immune Defense

(2008) Naoko Satoh-Takayama et al.   IMMUNITY

A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

(2008) Marina Cella et al.   NATURE

Influence of the transcription factor RORγt on the development of NKp46+ cell populations in gut and skin

(2008) Carmelo Luci et al.   NATURE IMMUNOLOGY

Human fetal lymphoid tissue–inducer cells are interleukin 17–producing precursors to RORC+ CD127+ natural killer–like cells

(2008) Tom Cupedo et al.   NATURE IMMUNOLOGY