A pH and solvent optimized reverse-phase ion-paring-LC–MS/MS method that leverages multiple scan-types for targeted absolute quantification of intracellular metabolites

Fast Swinnex filtration (FSF): a fast and robust sampling and extraction method suitable for metabolomics analysis of cultures grown in complex media

(2014) Douglas McCloskey et al.   Metabolomics

A model-driven quantitative metabolomics analysis of aerobic and anaerobic metabolism inE. coliK-12 MG1655 that is biochemically and thermodynamically consistent

(2013) Douglas McCloskey et al.   BIOTECHNOLOGY AND BIOENGINEERING

Changes in substrate availability in Escherichia coli lead to rapid metabolite, flux and growth rate responses

(2013) Hilal Taymaz-Nikerel et al.   METABOLIC ENGINEERING

Validation of a dual LC–HRMS platform for clinical metabolic diagnosis in serum, bridging quantitative analysis and untargeted metabolomics

(2013) Ilya Gertsman et al.   Metabolomics

Systematic identification of allosteric protein-metabolite interactions that control enzyme activity in vivo

(2013) Hannes Link et al.   NATURE BIOTECHNOLOGY

Steady-State Metabolite Concentrations Reflect a Balance between Maximizing Enzyme Efficiency and Minimizing Total Metabolite Load

(2013) Naama Tepper et al.   PLoS One

Functioning of a metabolic flux sensor in Escherichia coli

(2013) K. Kochanowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Consistent Estimation of Gibbs Energy Using Component Contributions

(2013) Elad Noor et al.   PLoS Computational Biology

Metabolic regulation analysis of wild-type and arcA mutant Escherichia coli under nitrate conditions using different levels of omics data

(2012) Yoshihiro Toya et al.   Molecular BioSystems

Regulation of Yeast Pyruvate Kinase by Ultrasensitive Allostery Independent of Phosphorylation

(2012) Yi-Fan Xu et al.   MOLECULAR CELL

Ultrasensitive regulation of anapleurosis via allosteric activation of PEP carboxylase

(2012) Yi-Fan Xu et al.   Nature Chemical Biology

Improved ruggedness of an ion-pairing liquid chromatography/tandem mass spectrometry assay for the quantitative analysis of the triphosphate metabolite of a nucleoside reverse transcriptase inhibitor in peripheral blood mononuclear cells

(2012) Yue Zhao et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Global Network Reorganization During Dynamic Adaptations of Bacillus subtilis Metabolism

(2012) J. M. Buescher et al.   SCIENCE

An LC–MS-Based Chemical and Analytical Method for Targeted Metabolite Quantification in the Model Cyanobacterium Synechococcus sp. PCC 7002

(2011) Nicholas B. Bennette et al.   ANALYTICAL CHEMISTRY

iAB-RBC-283: A proteomically derived knowledge-base of erythrocyte metabolism that can be used to simulate its physiological and patho-physiological states

(2011) Aarash Bordbar et al.   BMC Systems Biology

Escherichia coli responds with a rapid and large change in growth rate upon a shift from glucose-limited to glucose-excess conditions

(2011) Hilal Taymaz-Nikerel et al.   METABOLIC ENGINEERING

α-ketoglutarate coordinates carbon and nitrogen utilization via enzyme I inhibition

(2011) Christopher D Doucette et al.   Nature Chemical Biology

Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol

(2011) Harry Yim et al.   Nature Chemical Biology

Comparison between triple quadrupole, time of flight and hybrid quadrupole time of flight analysers coupled to liquid chromatography for the detection of anabolic steroids in doping control analysis

(2010) Oscar J. Pozo et al.   ANALYTICA CHIMICA ACTA

Ultrahigh Performance Liquid Chromatography−Tandem Mass Spectrometry Method for Fast and Robust Quantification of Anionic and Aromatic Metabolites

(2010) Joerg Martin Buescher et al.   ANALYTICAL CHEMISTRY

Nucleotide and Nucleotide Sugar Analysis by Liquid Chromatography-Electrospray Ionization-Mass Spectrometry on Surface-Conditioned Porous Graphitic Carbon

(2010) Martin Pabst et al.   ANALYTICAL CHEMISTRY

Metabolomic Analysis via Reversed-Phase Ion-Pairing Liquid Chromatography Coupled to a Stand Alone Orbitrap Mass Spectrometer

(2010) Wenyun Lu et al.   ANALYTICAL CHEMISTRY

Genome-derived minimal metabolic models for Escherichia coli MG1655 with estimated in vivo respiratory ATP stoichiometry

(2010) Hilal Taymaz-Nikerel et al.   BIOTECHNOLOGY AND BIOENGINEERING

Aqueous normal phase retention of nucleotides on silica hydride-based columns: Method development strategies for analytes revelant in clinical analysis

(2010) Maria T. Matyska et al.   JOURNAL OF SEPARATION SCIENCE

HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology

(2010) Christoph Gille et al.   Molecular Systems Biology

Blueprint for antimicrobial hit discovery targeting metabolic networks

(2010) Y. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of highly polar metabolites in human plasma by ultra-performance hydrophilic interaction liquid chromatography coupled with quadrupole-time of flight mass spectrometry

(2009) Xiaoming Cai et al.   ANALYTICA CHIMICA ACTA

Cross-Platform Comparison of Methods for Quantitative Metabolomics of Primary Metabolism

(2009) Jörg Martin Büscher et al.   ANALYTICAL CHEMISTRY

Systematic phenome analysis of Escherichia coli multiple-knockout mutants reveals hidden reactions in central carbon metabolism

(2009) Kenji Nakahigashi et al.   Molecular Systems Biology

Metabolomics-driven quantitative analysis of ammonia assimilation in E. coli

(2009) Jie Yuan et al.   Molecular Systems Biology

Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli

(2009) Bryson D Bennett et al.   Nature Chemical Biology

anNET: a tool for network-embedded thermodynamic analysis of quantitative metabolome data

(2008) Nicola Zamboni et al.   BMC BIOINFORMATICS

Analytical strategies for LC–MS-based targeted metabolomics

(2008) Wenyun Lu et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Comparison of Time-of-Flight Mass Spectrometry to Triple Quadrupole Tandem Mass Spectrometry for Quantitative Bioanalysis: Application to Antipsychotics

(2008) Leah N. Williamson et al.   JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES