Steady-State Metabolite Concentrations Reflect a Balance between Maximizing Enzyme Efficiency and Minimizing Total Metabolite Load

Quantitative Assignment of Reaction Directionality in a Multicompartmental Human Metabolic Reconstruction

(2012) H.S. Haraldsdóttir et al.   BIOPHYSICAL JOURNAL

Global Network Reorganization During Dynamic Adaptations of Bacillus subtilis Metabolism

(2012) J. M. Buescher et al.   SCIENCE

System-Level Insights into Yeast Metabolism by Thermodynamic Analysis of Elementary Flux Modes

(2012) Stefan J. Jol et al.   PLoS Computational Biology

Metabolome Remodeling during the Acidogenic-Solventogenic Transition in Clostridium acetobutylicum

(2011) Daniel Amador-Noguez et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Recommendations for terminology and databases for biochemical thermodynamics

(2011) Robert A. Alberty et al.   BIOPHYSICAL CHEMISTRY

Hydrophobicity and Charge Shape Cellular Metabolite Concentrations

(2011) Arren Bar-Even et al.   PLoS Computational Biology

Streamlining the construction of large-scale dynamic models using generic kinetic equations

(2010) Delali A. Adiamah et al.   BIOINFORMATICS

What is flux balance analysis?

(2010) Jeffrey D Orth et al.   NATURE BIOTECHNOLOGY

Quantifying E. coli Proteome and Transcriptome with Single-Molecule Sensitivity in Single Cells

(2010) Y. Taniguchi et al.   SCIENCE

Predicting metabolic engineering knockout strategies for chemical production: accounting for competing pathways

(2009) N. Tepper et al.   BIOINFORMATICS

Influence of uncertainties in pH, pMg, activity coefficients, metabolite concentrations, and other factors on the analysis of the thermodynamic feasibility of metabolic pathways

(2009) Vojislav Vojinović et al.   BIOTECHNOLOGY AND BIOENGINEERING

Kinetic hybrid models composed of mechanistic and simplified enzymatic rate laws - a promising method for speeding up the kinetic modelling of complex metabolic networks

(2009) Sascha Bulik et al.   FEBS Journal

Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli

(2009) Bryson D Bennett et al.   Nature Chemical Biology

Genome-scale reconstruction and in silico analysis of the Clostridium acetobutylicum ATCC 824 metabolic network

(2008) Joungmin Lee et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Group Contribution Method for Thermodynamic Analysis of Complex Metabolic Networks

(2008) Matthew D. Jankowski et al.   BIOPHYSICAL JOURNAL

Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy

(2008) Joshua Munger et al.   NATURE BIOTECHNOLOGY

BRENDA, AMENDA and FRENDA the enzyme information system: new content and tools in 2009

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