Targeting of the signal transducer Smo links microRNA-326 to the oncogenic Hedgehog pathway in CD34+CML stem/progenitor cells

Targeting hedgehog in hematologic malignancy

(2012) D. A. Irvine et al.   BLOOD

The extracellular loops of Smoothened play a regulatory role in control of Hedgehog pathway activation

(2012) C. E. Carroll et al.   DEVELOPMENT

Aberrant microRNA expression and its implications in the pathogenesis of leukemias

(2012) Sadegh Babashah et al.   CELLULAR ONCOLOGY

microRNAs: Master Regulators as Potential Therapeutics in Cancer

(2011) Michela Garofalo et al.   Annual Review of Pharmacology and Toxicology

The oncogenic and tumour suppressive roles of microRNAs in cancer and apoptosis

(2011) Sadegh Babashah et al.   EUROPEAN JOURNAL OF CANCER

Activation of the hedgehog pathway in chronic myelogeneous leukemia patients

(2011) Bing Long et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Novel therapeutic approach to eradicate tyrosine kinase inhibitor resistant chronic myeloid leukemia stem cells

(2010) Kazuhito Naka et al.   CANCER SCIENCE

MicroRNAs in Leukemias: Emerging Diagnostic Tools and Therapeutic Targets

(2010) Yousaf A. Mian et al.   CURRENT DRUG TARGETS

microRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia

(2010) Yoon-Chi Han et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hedgehog signaling maintains chemoresistance in myeloid leukemic cells

(2010) K C S Queiroz et al.   ONCOGENE

MicroRNAs in Cancer

(2009) Ramiro Garzon et al.   Annual Review of Medicine

Drug resistance is dramatically restored by hedgehog inhibitors in CD34+ leukemic cells

(2009) Masayoshi Kobune et al.   CANCER SCIENCE

Hedgehog Signaling Is Dispensable for Adult Hematopoietic Stem Cell Function

(2009) Jie Gao et al.   Cell Stem Cell

MicroRNA expression profiling in Imatinib-resistant Chronic Myeloid Leukemia patients without clinically significant ABL1-mutations

(2009) Edurne San José-Enériz et al.   Molecular Cancer

Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia

(2009) Chen Zhao et al.   NATURE

MicroRNAs: Biogenesis and Molecular Functions

(2008) Xuhang Liu et al.   BRAIN PATHOLOGY

Expansion of Bcr-Abl-Positive Leukemic Stem Cells Is Dependent on Hedgehog Pathway Activation

(2008) Christine Dierks et al.   CANCER CELL

Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells

(2008) Elisabetta Ferretti et al.   EMBO JOURNAL

Pancreatic Cancer Stem Cells

(2008) Cheong J. Lee et al.   JOURNAL OF CLINICAL ONCOLOGY

MicroRNAs and noncoding RNAs in hematological malignancies: molecular, clinical and therapeutic implications

(2008) M Fabbri et al.   LEUKEMIA