microRNAs: Master Regulators as Potential Therapeutics in Cancer

Cell cycle control of microRNA-mediated translation regulation

(2011) Shobha Vasudevan et al.   CELL CYCLE

The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia

(2010) Ulf Klein et al.   CANCER CELL

MicroRNA Cluster 221-222 and Estrogen Receptor α Interactions in Breast Cancer

(2010) Gianpiero Di Leva et al.   JNCI-Journal of the National Cancer Institute

Regulating A549 cells growth by ASO inhibiting miRNA expression

(2010) Ping-Yu Wang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Aberrant overexpression of microRNAs activate AKT signaling via down-regulation of tumor suppressors in natural killer-cell lymphoma/leukemia

(2009) Y. Yamanaka et al.   BLOOD

MicroRNA 29b functions in acute myeloid leukemia

(2009) R. Garzon et al.   BLOOD

miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation

(2009) Michela Garofalo et al.   CANCER CELL

miR-15a and miR-16 Are Implicated in Cell Cycle Regulation in a Rb-Dependent Manner and Are Frequently Deleted or Down-regulated in Non–Small Cell Lung Cancer

(2009) Nora Bandi et al.   CANCER RESEARCH

MicroRNA-34a Inhibits Glioblastoma Growth by Targeting Multiple Oncogenes

(2009) Y. Li et al.   CANCER RESEARCH

miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer

(2009) Elena Gallardo et al.   CARCINOGENESIS

miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma

(2009) Mayuko Furuta et al.   CARCINOGENESIS

Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

(2009) Janaiah Kota et al.   CELL

RETRACTED: A Pleiotropically Acting MicroRNA, miR-31, Inhibits Breast Cancer Metastasis

(2009) Scott Valastyan et al.   CELL

The microRNA miR-92 increases proliferation of myeloid cells and by targeting p63 modulates the abundance of its isoforms

(2009) Isabella Manni et al.   FASEB JOURNAL

Elevated expression of microRNAs 155, 203, 210 and 222 in pancreatic tumors is associated with poorer survival

(2009) Thomas Greither et al.   INTERNATIONAL JOURNAL OF CANCER

Cationic Lipid Formulations Alter the In Vivo Tropism of AAV2/9 Vector in Lung

(2009) David E Fein et al.   MOLECULAR THERAPY

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural determinants of miRNAs for RISC loading and slicer-independent unwinding

(2009) Tomoko Kawamata et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Antisense Inhibition of microRNA-21 or -221 Arrests Cell Cycle, Induces Apoptosis, and Sensitizes the Effects of Gemcitabine in Pancreatic Adenocarcinoma

(2009) Jong-Kook Park et al.   PANCREAS

miR-221 overexpression contributes to liver tumorigenesis

(2009) P. Pineau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes

(2008) M. Inomata et al.   BLOOD

MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia

(2008) R. Garzon et al.   BLOOD

E2F1-Regulated MicroRNAs Impair TGFβ-Dependent Cell-Cycle Arrest and Apoptosis in Gastric Cancer

(2008) Fabio Petrocca et al.   CANCER CELL

The Promyelocytic Leukemia Zinc Finger-MicroRNA-221/-222 Pathway Controls Melanoma Progression through Multiple Oncogenic Mechanisms

(2008) F. Felicetti et al.   CANCER RESEARCH

MicroRNA-21 targets tumor suppressor genes in invasion and metastasis

(2008) Shuomin Zhu et al.   CELL RESEARCH

Potential of AAV vectors in the treatment of metabolic disease

(2008) I E Alexander et al.   GENE THERAPY

MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma

(2008) Wei-Chih Tsai et al.   HEPATOLOGY

Not miR-ly small RNAs: Big potential for microRNAs in therapy

(2008) Tara M. Love et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

miR-21 Gene Expression Triggered by AP-1 Is Sustained through a Double-Negative Feedback Mechanism

(2008) Shuji Fujita et al.   JOURNAL OF MOLECULAR BIOLOGY

MicroRNA-21 Targets Sprouty2 and Promotes Cellular Outgrowths

(2008) Danish Sayed et al.   MOLECULAR BIOLOGY OF THE CELL

A Functional Screen Identifies miR-34a as a Candidate Neuroblastoma Tumor Suppressor Gene

(2008) K. A. Cole et al.   MOLECULAR CANCER RESEARCH

Endogenous human microRNAs that suppress breast cancer metastasis

(2008) Sohail F. Tavazoie et al.   NATURE

LNA-mediated microRNA silencing in non-human primates

(2008) Joacim Elmén et al.   NATURE

The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

(2008) Désirée Bonci et al.   NATURE MEDICINE

miR-29 miRNAs activate p53 by targeting p85α and CDC42

(2008) Seong-Yeon Park et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer

(2008) M Garofalo et al.   ONCOGENE

MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma

(2008) F Fornari et al.   ONCOGENE