Aberrant microRNA expression and its implications in the pathogenesis of leukemias

microRNAs: Master Regulators as Potential Therapeutics in Cancer

(2011) Michela Garofalo et al.   Annual Review of Pharmacology and Toxicology

Control of cell proliferation pathways by microRNAs

(2011) María José Bueno et al.   CELL CYCLE

The oncogenic and tumour suppressive roles of microRNAs in cancer and apoptosis

(2011) Sadegh Babashah et al.   EUROPEAN JOURNAL OF CANCER

MicroRNAs in acute leukemia: from biological players to clinical contributors

(2011) D Schotte et al.   LEUKEMIA

Expression patterns of microRNAs associated with CML phases and their disease related targets

(2011) Kateřina Machová Poláková et al.   Molecular Cancer

microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia

(2010) D. Asslaber et al.   BLOOD

The prognostic and functional role of microRNAs in acute myeloid leukemia

(2010) G. Marcucci et al.   BLOOD

microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival

(2010) S. Rossi et al.   BLOOD

Micro-RNAs and their potential target genes in leukemia pathogenesis

(2010) Chunjuan Dong et al.   CANCER BIOLOGY & THERAPY

The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia

(2010) Ulf Klein et al.   CANCER CELL

The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression

(2010) Piu Wong et al.   CANCER RESEARCH

MicroRNAs in malignant progression

(2010) Li Ma et al.   CELL CYCLE

MicroRNAs in Leukemias: Emerging Diagnostic Tools and Therapeutic Targets

(2010) Yousaf A. Mian et al.   CURRENT DRUG TARGETS

Oncoproteins, heterochromatin silencing and microRNAs: a new link for leukemogenesis

(2010) Clara Nervi et al.   Epigenetics

miR signatures and the role of miRs in acute myeloid leukaemia

(2010) Hugo Seca et al.   EUROPEAN JOURNAL OF CANCER

Micro-RNA response to imatinib mesylate in patients with chronic myeloid leukemia

(2010) S. Flamant et al.   HAEMATOLOGICA

Determination of genes and microRNAs involved in the resistance to fludarabine in vivo in chronic lymphocytic leukemia

(2010) Etienne Moussay et al.   Molecular Cancer

Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia

(2010) Konstantinos J. Mavrakis et al.   NATURE CELL BIOLOGY

Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia

(2010) Shuangli Mi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New insights into the pathogenesis of chronic lymphocytic leukemia

(2010) Ulf Klein et al.   SEMINARS IN CANCER BIOLOGY

MicroRNAs in Cancer

(2009) Ramiro Garzon et al.   Annual Review of Medicine

microRNA-29c and microRNA-223 down-regulation has in vivo significance in chronic lymphocytic leukemia and improves disease risk stratification

(2009) B. Stamatopoulos et al.   BLOOD

Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization

(2009) R. Popovic et al.   BLOOD

MicroRNA and leukemia: Tiny molecule, great function

(2009) Haifeng Zhao et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Emerging Treatments in Acute Lymphoblastic Leukemia

(2009) R. Crazzolara et al.   CURRENT CANCER DRUG TARGETS

MicroRNAs: Predictors and modifiers of chemo- and radiotherapy in different tumour types

(2009) Richard Hummel et al.   EUROPEAN JOURNAL OF CANCER

Genetic dissection of the miR-17 92 cluster of microRNAs in Myc-induced B-cell lymphomas

(2009) P. Mu et al.   GENES & DEVELOPMENT

miR-19 is a key oncogenic component of mir-17-92

(2009) V. Olive et al.   GENES & DEVELOPMENT

MicroRNAs: Potential biomarkers for cancer diagnosis, prognosis and targets for therapy

(2009) William C.S. Cho   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Favorable Prognostic Impact ofNPM1Mutations in Older Patients With Cytogenetically Normal De Novo Acute Myeloid Leukemia and Associated Gene- and MicroRNA-Expression Signatures: A Cancer and Leukemia Group B Study

(2009) Heiko Becker et al.   JOURNAL OF CLINICAL ONCOLOGY

The role of microRNA in human leukemia: a review

(2009) S Yendamuri et al.   LEUKEMIA

MicroRNA expression profiling in Imatinib-resistant Chronic Myeloid Leukemia patients without clinically significant ABL1-mutations

(2009) Edurne San José-Enériz et al.   Molecular Cancer

Correcting miR-15a/16 genetic defect in New Zealand Black mouse model of CLL enhances drug sensitivity

(2009) E. Salerno et al.   MOLECULAR CANCER THERAPEUTICS

Down-Regulation of miR-92 in Human Plasma Is a Novel Marker for Acute Leukemia Patients

(2009) Masami Tanaka et al.   PLoS One

MicroRNA Patterns Associated with Clinical Prognostic Parameters and CNS Relapse Prediction in Pediatric Acute Leukemia

(2009) Hua Zhang et al.   PLoS One

High BAALC expression associates with other molecular prognostic markers, poor outcome, and a distinct gene-expression signature in cytogenetically normal patients younger than 60 years with acute myeloid leukemia: a Cancer and Leukemia Group B (CALGB) study

(2008) C. Langer et al.   BLOOD

Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma

(2008) R. W. Chen et al.   BLOOD

MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes

(2008) M. Inomata et al.   BLOOD

MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia

(2008) R. Garzon et al.   BLOOD

MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia

(2008) M. Jongen-Lavrencic et al.   BLOOD

Specific activation of microRNA106b enables the p73 apoptotic response in chronic lymphocytic leukemia by targeting the ubiquitin ligase Itch for degradation

(2008) D. Sampath et al.   BLOOD

miR-34a as part of the resistance network in chronic lymphocytic leukemia

(2008) T. Zenz et al.   BLOOD

MicroRNAs: Biogenesis and Molecular Functions

(2008) Xuhang Liu et al.   BRAIN PATHOLOGY

Genetic and Epigenetic Silencing of MicroRNA-203 Enhances ABL1 and BCR-ABL1 Oncogene Expression

(2008) María J. Bueno et al.   CANCER CELL

Modulation of miRNA activity in human cancer: a new paradigm for cancer gene therapy?

(2008) A W Tong et al.   CANCER GENE THERAPY

Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters

(2008) Andrea Ventura et al.   CELL

MicroRNAs in normal and malignant hematopoiesis

(2008) Ramiro Garzon et al.   CURRENT OPINION IN HEMATOLOGY

A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation

(2008) Zuoren Yu et al.   JOURNAL OF CELL BIOLOGY

Prognostic Significance of, and Gene and MicroRNA Expression Signatures Associated With,CEBPAMutations in Cytogenetically Normal Acute Myeloid Leukemia With High-Risk Molecular Features: A Cancer and Leukemia Group B Study

(2008) Guido Marcucci et al.   JOURNAL OF CLINICAL ONCOLOGY

Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder

(2008) Ryan M. O'Connell et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Myeloid cell differentiation arrest by miR-125b-1 in myelodysplasic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation

(2008) Marina Bousquet et al.   JOURNAL OF EXPERIMENTAL MEDICINE

17p13/TP53 deletion in B-CLL patients is associated with microRNA-34a downregulation

(2008) M K Dijkstra et al.   LEUKEMIA

Identification of new microRNA genes and aberrant microRNA profiles in childhood acute lymphoblastic leukemia

(2008) D Schotte et al.   LEUKEMIA

MicroRNAs and noncoding RNAs in hematological malignancies: molecular, clinical and therapeutic implications

(2008) M Fabbri et al.   LEUKEMIA

Down-Regulation of hsa-miR-10a in Chronic Myeloid Leukemia CD34+ Cells Increases USF2-Mediated Cell Growth

(2008) X. Agirre et al.   MOLECULAR CANCER RESEARCH

Regulation of progenitor cell proliferation and granulocyte function by microRNA-223

(2008) Jonathan B. Johnnidis et al.   NATURE

LNA-mediated microRNA silencing in non-human primates

(2008) Joacim Elmén et al.   NATURE

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

(2008) Changchun Xiao et al.   NATURE IMMUNOLOGY

MicroRNA Expression in Cytogenetically Normal Acute Myeloid Leukemia

(2008) Guido Marcucci et al.   NEW ENGLAND JOURNAL OF MEDICINE

The MYCN oncogene is a direct target of miR-34a

(2008) J S Wei et al.   ONCOGENE

Distinctive Patterns of MicroRNA Expression Associated with Karyotype in Acute Myeloid Leukaemia

(2008) Amanda Dixon-McIver et al.   PLoS One

Serum MicroRNAs Are Promising Novel Biomarkers

(2008) Shlomit Gilad et al.   PLoS One

MiR-15a and miR-16-1 cluster functions in human leukemia

(2008) George A. Calin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct microRNA expression profiles in acute myeloid leukemia with common translocations

(2008) Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-34a repression of SIRT1 regulates apoptosis

(2008) M. Yamakuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin

(2008) R. Garzon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA